Inventors:
Evelyn Mary McKeegan - Lake Forest IL, US
Saul A. Datwyler - Evanston IL, US
David J. Hawksworth - Lake Villa IL, US
Don M. Laird - Mundelein IL, US
Dominick L. Pucci - Libertyville IL, US
David C. Sogin - Highland Park IL, US
Joan D. Tyner - Beach Park IL, US
Robert N. Ziemann - Lindenhurst IL, US
Peter James Ansell - Grayslake IL, US
Ke K. Zhang - Glenview IL, US
Assignee:
ABBOTT LABORATORIES - Abbott Park IL
International Classification:
A61K 31/416
G01N 33/566
A61P 35/00
Abstract:
The present disclosure relates to, among other things, methods for determining whether a subject receiving treatment with a drug has obtained an efficacious blood level of the drug. Moreover, the present disclosure also relates to methods of determining whether a subject predisposed to or suffering from a disease will benefit from treatment with a drug, and the response of a subject receiving treatment (e.g., such as for cancer) by monitoring biomarkers of angiogenesis. In particular, the disclosure relates to PlGF-1 companion diagnostic methods and products.