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Paul G Warrener

from Gaithersburg, MD
Age ~59

Paul Warrener Phones & Addresses

  • 518 Helene St, Gaithersburg, MD 20878 (301) 538-5956
  • 2803 67Th St, Seattle, WA 98117 (206) 783-5525
  • Rockville, MD
  • 518 Helene St, Gaithersburg, MD 20878

Work

Company: Medimmune/astrazeneca Aug 2009 Position: Scientist

Education

Degree: Associate degree or higher

Skills

Molecular Biology • Assay Development • Drug Discovery • Biotechnology • Elisa • Life Sciences • Immunology • In Vitro • Lifesciences • Clinical Development • High Throughput Screening • Biochemistry • Drug Development • Cell • Cell Culture • Protein Chemistry • Cell Biology • Genomics • Pharmaceutical Industry • Western Blotting • Biopharmaceuticals • Protein Purification • Technology Transfer • In Vivo • Biomarkers • Bacterial Genetics • Genetics • Flow Cytometry • Infectious Diseases • Microbiology • Dna Sequencing

Industries

Biotechnology

Resumes

Resumes

Paul Warrener Photo 1

Scientist

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Location:
Washington, DC
Industry:
Biotechnology
Work:
MedImmune/AstraZeneca since Aug 2009
Scientist

Targeted Growth 2008 - 2009
Scientist

Rosetta Inpharmatics 2002 - 2008
Scientist

PathoGenesis 1993 - 2001
Scientist

MedImmune - Maryland 1990 - 1993
Research Associate
Skills:
Molecular Biology
Assay Development
Drug Discovery
Biotechnology
Elisa
Life Sciences
Immunology
In Vitro
Lifesciences
Clinical Development
High Throughput Screening
Biochemistry
Drug Development
Cell
Cell Culture
Protein Chemistry
Cell Biology
Genomics
Pharmaceutical Industry
Western Blotting
Biopharmaceuticals
Protein Purification
Technology Transfer
In Vivo
Biomarkers
Bacterial Genetics
Genetics
Flow Cytometry
Infectious Diseases
Microbiology
Dna Sequencing

Publications

Us Patents

Random Transposon Insertion In And Use Thereof To Identify Essential Genes

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US Patent:
8173363, May 8, 2012
Filed:
Aug 20, 2003
Appl. No.:
10/525062
Inventors:
Kim Folger Bruce - Seattle WA, US
Paul Warrener - Seattle WA, US
Jennifer McLarnan - Everett WA, US
Kevin Hou - Issaquah WA, US
Assignee:
Novartis Vaccines and Diagnostics, Inc. - Emeryville CA
International Classification:
C12Q 1/68
C07H 21/04
G01N 33/48
US Classification:
435 6, 536 231, 536 241, 702 19, 702 20
Abstract:
The invention provides a method for generating a database of candidate essential genes in , as well as otherwise important genes that, when mutated, lead to a growth attenuated phenotype. Such genes and mutants of such genes are important for identifying antibacterial agents suitable for treating and preventing infections. The invention includes methods for confirming the essentiality or importance of candidate genes, as well as methods for utilizing those genes to screen for new antibacterial drugs. The invention also includes the antibacterial agents identified using the disclosed methods, as well as methods of using the same for treating and preventing infection.

Modified Photosynthetic Microorganisms For Producing Triglycerides

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US Patent:
8394614, Mar 12, 2013
Filed:
Jun 4, 2010
Appl. No.:
12/794536
Inventors:
James Roberts - Seattle WA, US
Fred Cross - Seattle WA, US
Paul Warrener - Seattle WA, US
Ernesto Javier Munoz - Seattle WA, US
Martin Henry Lee - Seattle WA, US
Khadidja Romari - Seattle WA, US
Kimberly Marie Kotovic - Seattle WA, US
Jason W. Hickman - Seattle WA, US
Assignee:
Matrix Genetics, LLC - Seattle WA
International Classification:
C12P 5/00
C12P 1/04
C12N 1/22
US Classification:
435170, 435 41, 435243, 4352521
Abstract:
This disclosure describes genetically modified photosynthetic microorganisms, including Cyanobacteria, that contain one or more exogenous genes encoding a diacylglycerol acyltransferase, a phosphatidate phosphatase, and/or an acetyl-CoA carboxylase, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.

Modified Photosynthetic Microorganisms For Producing Triglycerides

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US Patent:
8394621, Mar 12, 2013
Filed:
Oct 23, 2009
Appl. No.:
12/605204
Inventors:
James Roberts - Seattle WA, US
Fred Cross - Seattle WA, US
Paul Warrener - Seattle WA, US
Ernesto Javier Munoz - Seattle WA, US
Martin Henry Lee - Seattle WA, US
Khadidja Romari - Seattle WA, US
Kimberly Marie Kotovic - Seattle WA, US
Jason W. Hickman - Seattle WA, US
Assignee:
Matrix Genetrics, LLC - Seattle WA
International Classification:
C12P 5/00
C12P 1/04
C12N 1/22
US Classification:
4352521, 435 41, 435170, 435243
Abstract:
This disclosure describes genetically modified photosynthetic microorganisms, including Cyanobacteria, that contain one or more exogenous genes encoding a diacylglycerol acyltransferase, a phosphatidate phosphatase, and/or an acetyl-CoA carboxylase, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.

Essential And Important Genes Of Pseudomonas Aeruginosa And The Use Thereof To Design Or Identify Antibacterial Agents

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US Patent:
20070196829, Aug 23, 2007
Filed:
Oct 11, 2005
Appl. No.:
11/246458
Inventors:
Kim Bruce - Seattle WA, US
Paul Warrener - Seattle WA, US
Kevin Hou - Issaquah WA, US
Assignee:
CHIRON CORPORATION - Emeryville CA
International Classification:
C12Q 1/68
C12Q 1/18
US Classification:
435006000, 435032000
Abstract:
The invention includes a database of candidate essential genes in , as well as other important genes that, when mutated, lead to a growth attenuated phenotype. Such genes and mutants of such genes are important for identifying antibacterial agents suitable for treating and preventing infections. The invention includes methods for confirming the essentiality or importance of candidate genes, as well as methods for utilizing those genes to screen for new antibacterial drugs. The invention also includes the antibacterial agents identified using the disclosed methods, as well as methods of using the same for treating and preventing infection.

Modified Photosynthetic Microorganisms With Reduced Glycogen And Their Use In Producing Carbon-Based Products

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US Patent:
20100184169, Jul 22, 2010
Filed:
Dec 22, 2009
Appl. No.:
12/645228
Inventors:
James Roberts - Seattle WA, US
Fred Cross - Seattle WA, US
Paul Warrener - Seattle WA, US
Kimberly Marie Kotovic - Seattle WA, US
Margaret Mary McCormick - Seattle WA, US
Assignee:
TARGETED GROWTH, INC. - Seattle WA
International Classification:
C12P 7/64
C12N 1/21
C12P 1/04
US Classification:
435134, 4352523, 435170
Abstract:
This disclosure describes genetically modified photosynthetic microorganisms, including Cyanobacteria, that contain one or more mutations or deletions in a glycogen biosynthesis or storage pathway, which accumulate a reduced amount of glycogen as compared to a wild type , and which are capable of producing an increased amount of lipids and/or fatty acids. In certain embodiments, the genetically modified photosynthetic microorganisms also contain one or more exogenous genes encoding a diacyglycerol acyltransferase, a phosphatidate phosphatase, and/or an acetyl-CoA carboxylase, and which are capable of producing increased amounts of lipids or fatty acids and/or synthesizing triglycerides.

Modified Photosynthetic Microorganisms For Producing Lipids

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US Patent:
20110250659, Oct 13, 2011
Filed:
Apr 5, 2011
Appl. No.:
13/080496
Inventors:
James Roberts - Seattle WA, US
Fred Cross - Seattle WA, US
Paul Warrener - Seattle WA, US
Ernesto Javier Munoz - Seatte WA, US
Jason W. Hickman - Seattle WA, US
Assignee:
TARGETED GROWTH, INC. - Seattle WA
International Classification:
C12P 7/64
C12N 15/74
C12N 1/13
US Classification:
435134, 4352572, 435471
Abstract:
This disclosure describes genetically modified photosynthetic microorganisms, e.g., Cyanobacteria, that contain one or more exogenous genes encoding a phospholipase and/or thioesterase, which are capable of producing an increased amount of lipids and/or fatty acids. This disclosure also describes genetically modified photosynthetic microorganisms that contain one or more exogenous genes encoding a diacyglycerol acyltransferase, a phosphatidate phosphatase, and/or an acetyl-CoA carboxylase, which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides, as well as photosynthetic microorganism comprising mutations or deletions in a glycogen biosynthesis or storage pathway, which accumulate a reduced amount of glycogen under reduced nitrogen conditions as compared to a wild type photosynthetic microorganism.

Modified Photosynthetic Microorganisms For Producing Triglycerides

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US Patent:
20130143284, Jun 6, 2013
Filed:
Feb 6, 2013
Appl. No.:
13/761025
Inventors:
MATRIX GENETICS, LLC - Seattle WA, US
Fred Cross - Seattle WA, US
Paul Warrener - Seattle WA, US
Ernesto Javier Munoz - Seattle WA, US
Martin Henry Lee - Seattle WA, US
Khadidja Romari - Seattle WA, US
Kimberly Marie Kotovic - Seattle WA, US
Jason W. Hickman - Seattle WA, US
Assignee:
MATRIX GENETICS, LLC - Seattle WA
International Classification:
C12N 15/79
US Classification:
435134, 4352572, 435477
Abstract:
This disclosure describes genetically modified photosynthetic microorganisms, including Cyanobacteria, that contain one or more exogenous genes encoding a diacyglycerol acyltransferase, a phosphatidate phosphatase, and/or an acetyl-CoA carboxylase, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.

Combination Therapies Using Anti-Pseudomonas Psl And Pcrv Binding Molecules

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US Patent:
20220177554, Jun 9, 2022
Filed:
Nov 15, 2021
Appl. No.:
17/454837
Inventors:
- Cambridge, GB
Paul WARRENER - Gaithersburg MD, US
Charles STOVER - Gaithersburg MD, US
Bret SELLMAN - Gaithersburg MD, US
Ralph MINTER - Cambrige, GB
Sandrine GUILLARD - Cambridge, GB
Steven RUST - Cambridge, GB
Mladen TOMICH - Exton PA, US
Vignesh VENKATRAMAN - Cambridge, GB
Reena VARKEY - Gaithersburg MD, US
Li PENG - Gaithersburg MD, US
Melissa DAMSCHRODER - Gaithersburg MD, US
Partha S. CHOWDHURY - Gaithersburg MD, US
Nazzareno DIMASI - Gaithersburg MD, US
Ryan FLEMING - Gaithersburg MD, US
Binyam BEZABEH - Gaithersburg MD, US
Changshou GAO - Gaithersburg MD, US
Godfrey RAINEY - Gaithersburg MD, US
Cuihua GAO - Gaithersburg MD, US
International Classification:
C07K 16/12
Abstract:
This disclosure relates to combination therapies comprising anti-Psl and PcrV binding molecules and related compositions, for use in prevention and treatment of infection.
Paul G Warrener from Gaithersburg, MD, age ~59 Get Report