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Paul Skonezny Phones & Addresses

  • Durham, NC

Publications

Us Patents

Monoheteroring Compounds And Their Use

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US Patent:
46031367, Jul 29, 1986
Filed:
Dec 30, 1983
Appl. No.:
6/567248
Inventors:
Susan M. Daluge - Chapel Hill NC
Paul M. Skonezny - Durham NC
International Classification:
C07D23949
A61K 31505
US Classification:
514275
Abstract:
Novel 2,4-diamino-5-(substituted naphthylmethyl)pyrimidines have been found to have superior antibacterial activity.

2,4-Diamino-(Substituted-Benzopyran(Quinolyl,Isoquinoly)Methyl)Pyrimidine S Useful As Antibacterials

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US Patent:
45873429, May 6, 1986
Filed:
Oct 31, 1983
Appl. No.:
6/546850
Inventors:
Susan M. Daluge - Chapel Hill NC
Paul M. Skonezny - Durham NC
International Classification:
C07D41906
A61K 31505
US Classification:
544324
Abstract:
Novel 2,4-diaminopyrimidines having substituted heterobicyclomethyl moieties in the 5-position have superior antibacterial properties.

2,4-Diaminopyrimidines Substituted With Heterobicyclomethyl Radicals At The 5 Position Useful As Antibacterials

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US Patent:
47614757, Aug 2, 1988
Filed:
Mar 12, 1986
Appl. No.:
6/839463
Inventors:
Susan M. Daluge - Chapel Hill NC
Paul M. Skonezny - Durham NC
International Classification:
C07D23949
US Classification:
544324
Abstract:
Novel 2,4-diaminopyrimidines having substituted heterobicyclomethyl moieties in the 5-position have superior antibacterial properties.

Monoheteroring Compounds And Their Use

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US Patent:
44382677, Mar 20, 1984
Filed:
Nov 9, 1981
Appl. No.:
6/319644
Inventors:
Susan M. Daluge - Chapel Hill NC
Paul M. Skonezny - Durham NC
International Classification:
C07D23947
C07D23949
US Classification:
544309
Abstract:
Novel 2,4-diamino-5-(substituted naphthylmethyl)pyrimidines have been found to have superior antibacterial activity.

2,4-Diamino-5-(Substituted)Pyrimidines, Useful As Antimicrobials

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US Patent:
45902712, May 20, 1986
Filed:
Apr 29, 1983
Appl. No.:
6/490196
Inventors:
Susan M. Daluge - Chapel Hill NC
Paul M. Skonezny - Clay NY
Barbara Roth - Chapel Hill NC
Barbara S. Rauckman - Durham NC
Assignee:
Burroughs Wellcome Co. - Research Triangle Park NC
International Classification:
C07D23949
C07D40106
C07D40506
A61K 31505
US Classification:
544324
Abstract:
Compounds of the formula (II) ##STR1## or a salt, N-oxide or acyl derivative thereof, wherein Y is a group ##STR2## which is linked to the pyrimidinylmethyl moiety at the 1 or 7-position and is optionally substituted at the 2, 3, 4 or 6-position or at the 7-position when the linkage to the pyrimidinylmethyl moiety is at the 1-position wherein X is an oxygen or sulphur atom, a group CH. sub. 2, a group S(O). sub. n where n=1 or 2, a group NR. sup. 1 wherein R. sup. 1 is hydrogen C. sub. 1-4 alkyl or a group COR. sup. 2 where R. sup. 2 is hydrogen, C. sub. 1-4 alkoxy or amino and the dotted line represents a single or double bond, have antimicrobial activity. Processes for making these compounds, pharmaceutical compositions containing them and the medical use of the compounds are also disclosed.
Paul M Skonezny from Durham, NC Get Report