Patrick S Vallance

Endothelial dysfunction is now regarded as an early marker of vascular disease and therefore an important target for therapeutic intervention and discovery of novel treatments. Ideal for both basic and clinical scientists, whether in industry or academia, and physicians, Vascular Endothelium in Huma...

This easy to use program provides the means of showing patients their risk of heart disease and stroke, first over 10 years, then in relation to the general population of their age and sex. By introducing treatment options such as dropping smoking reduction of that risk is demonstrated. CardioRisk M...

In 1980, Furchgott and Zawadzki demonstrated that the ability of a blood vessel to relax to acetylcholine is entirely dependent upon the presence of an intact endothelium b1. This startlingly simple and elegant observation heralded a decade of basic research into endothelium-derived vasoactive facto...