US Patent:
20160369280, Dec 22, 2016
Inventors:
- Duarte CA, US
Dongho Kim - Beverly Hills CA, US
Patric Lundberg - Rancho Cucamonga CA, US
Edouard Cantin - Alhambra CA, US
International Classification:
C12N 15/113
C12N 15/117
Abstract:
Double-stranded and single-stranded RNA molecules, and their use in methods for inducing interferon are provided. The interferon induction provides anti-viral and other medically useful effects, such as anti-cancer effects. Also provided are methods for reducing or inhibiting interferon induction exhibited by such molecules, particularly siRNA and shRNA molecules produced in vitro.