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Omar Al Bazirgan

from Fair Oaks, CA
Age ~48
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Also known as:
Omar A Bazirgan, Omar Al M
Related to:
Nasir H Albazirgan, 64Hazar S Bazirgan, 79Thair K Bazirgan, 81Tahir K Bazirgan, 80Tahir K Bazirgan, 81
Connected to:
Colette C Bazis, 63Gary M Bazis, 59Gregory T Bazis, 42Greg D Baziuk, 78Philip M Baziw, 45Jack A Bazler, 84Raymond S Bazley, 60Thomas Bazley, 59Gwendolyn K Bazmore, 73Andrew E Bazner, 54

Omar Bazirgan Phones & Addresses

  • Fair Oaks, CA
  • 12111 Waverly Downs Ln, San Diego, CA 92128 (858) 673-4783
  • 3612 Miami St, Sacramento, CA 95821 (916) 487-3524
  • 9450 Gilman Dr, La Jolla, CA 92092 (858) 546-1464
  • 9162 Regents Rd, La Jolla, CA 92037 (858) 546-1464
  • Davis, CA

Resumes

Resumes

Omar Bazirgan Photo 1

Staff Scientist

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
Fabrus - La Jolla, CA since Mar 2013
Senior Scientist
Fabrus - La Jolla, CA Jun 2008 - Mar 2013
Scientist
University of California, San Diego Mar 2007 - Feb 2008
Postdoctoral Researcher
University of California, San Diego Sep 1999 - Dec 2006
Graduate Student Researcher
University of California, Davis Jun 1998 - Aug 1999
Postgraduate Researcher
Education:
University of California, San Diego 1999 - 2006
University of California, Davis 1994 - 1998
Skills:
Assay Development
Molecular Biology
Biochemistry
Antibodies
Protein Chemistry
Cell Biology
Protein Expression
Protein Purification
Flow Cytometry
Chemistry
High Throughput Screening
Recombinant Dna Technology
Data Analysis
Mammalian Cell Culture
Tissue Culture
Antibody Engineering
Affinity Maturation
Protein Engineering
Multi Color Flow Cytometry
Antibody Humanization
Ultra Long Cdr Antibodies
Gpcrs
Omar Bazirgan Photo 2

Scientist At Fabrus Llc

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Position:
Scientist at Fabrus, Inc.
Location:
La Jolla, California
Industry:
Biotechnology
Work:
Fabrus, Inc. since Jun 2008
Scientist
University of California, San Diego Mar 2007 - Feb 2008
Postdoctoral Researcher
University of California, San Diego Sep 1999 - Dec 2006
Graduate Student Researcher
University of California, Davis Jun 1998 - Aug 1999
Postgraduate Researcher
Education:
University of California, San Diego 1999 - 2006
University of California, Davis 1994 - 1998

Publications

Us Patents

Ultralong Complementarity Determining Regions And Uses Thereof

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US Patent:
20140050720, Feb 20, 2014
Filed:
Jan 9, 2013
Appl. No.:
13/737913
Inventors:
THE SCRIPPS RESEARCH INSTITUTE - , US
Omar A. Bazirgan - San Diego CA, US
Dan Ekiert - San Francisco CA, US
Hongyuan Helen Mao - San Diego CA, US
Peter Schultz - La Jolla CA, US
Feng Wang - Encinitas CA, US
Ian Wilson - La Jolla CA, US
Yong Zhang - San Diego CA, US
Assignee:
THE SCRIPPS RESEARCH INSTITUTE - La Jolla CA
International Classification:
C07K 16/10
C07K 16/46
US Classification:
4241331, 506 18, 506 16, 5303873, 536 2353, 4353201, 435 696, 43525233, 43525421, 43525423, 435328
Abstract:
Disclosed herein are immunoglobulin constructs comprising at least one immunoglobulin domain or fragment thereof; and a therapeutic polypeptide or derivative or variant thereof attached to or inserted into said immunoglobulin domain. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a knob domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said knob domain of the CDR3H. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a stalk domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said stalk domain of the CDR3H. Also described herein are methods and compositions comprising the immunoglobulin constructs described herein for treatment and prevention of a disease or condition in a subject.

Combinatorial Antibody Libraries And Uses Thereof

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US Patent:
20200399359, Dec 24, 2020
Filed:
Aug 25, 2020
Appl. No.:
17/002749
Inventors:
- San Diego CA, US
James GRAZIANO - San Diego CA, US
Helen Hongyuan MAO - San Diego CA, US
Byeong Doo SONG - Chuncheon, KR
Tyson CHASE - San Diego CA, US
Omar BAZIRGAN - San Diego CA, US
Assignee:
Taurus Biosciences, LLC - San Diego CA
International Classification:
C07K 16/22
C40B 50/08
C07K 16/00
C07K 16/18
C07K 16/28
C40B 40/08
C07K 16/32
C12N 15/10
G01N 33/68
Abstract:
Methods for making a combinatorial antibody library from human germline segments are provided. Also provided are libraries of nucleic acid molecules compiled from germline segments encoding VL chains and libraries of nucleic acid molecules encoding VH chains, and resulting antibody libraries. The libraries are provided as addressable libraries. Methods for screening antibody libraries against a target protein antigen, and the identified or selected antibodies are provided.

Humanized Antibodies

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US Patent:
20200223944, Jul 16, 2020
Filed:
Jan 6, 2020
Appl. No.:
16/735070
Inventors:
- La Jolla CA, US
Omar Bazirgan - San Diego CA, US
Hongyuan Helen Mao - San Diego CA, US
International Classification:
C07K 16/46
C07K 14/54
C07K 16/00
C07K 16/10
Abstract:
The present disclosure provides humanized antibodies, including antibodies comprising an ultralong CDR3 and uses thereof.

Ultralong Complementarity Determining Regions And Uses Thereof

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US Patent:
20200181241, Jun 11, 2020
Filed:
Jan 14, 2020
Appl. No.:
16/742759
Inventors:
- La Jolla CA, US
Omar A. BAZIRGAN - San Diego CA, US
Hongyuan Helen MAO - San Diego CA, US
Peter SCHULTZ - La Jolla CA, US
Feng WANG - Beijing, CN
Yong Zhang - Los Angeles CA, US
International Classification:
C07K 16/10
C07K 16/00
C07K 16/46
C07K 14/53
Abstract:
Disclosed herein are immunoglobulin constructs comprising at least one immunoglobulin domain or fragment thereof; and a therapeutic polypeptide or derivative or variant thereof attached to or inserted into said immunoglobulin domain. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a knob domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said knob domain of the CDR3H. Also provided are immunoglobulin constructs comprising a mammalian immunoglobulin heavy chain comprising at least a portion of a stalk domain in the complementarity-determining region 3 (CDR3H) or fragment thereof; and a therapeutic polypeptide attached to or inserted into said stalk domain of the CDR3H. Also described herein are methods and compositions comprising the immunoglobulin constructs described herein for treatment and prevention of a disease or condition in a subject.

Humanized Antibodies

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US Patent:
20180222999, Aug 9, 2018
Filed:
Nov 1, 2017
Appl. No.:
15/801251
Inventors:
- La Jolla CA, US
Omar A. BAZIRGAN - San Diego CA, US
Hongyuan Helen MAO - San Diego CA, US
International Classification:
C07K 16/46
C07K 14/54
C07K 16/10
C07K 16/00
Abstract:
The present disclosure provides humanized antibodies, including antibodies comprising an ultralong CDR3 and uses thereof.

Combinatorial Antibody Libraries And Uses Thereof

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US Patent:
20160194627, Jul 7, 2016
Filed:
Dec 4, 2015
Appl. No.:
14/959940
Inventors:
- SAN DIEGO CA, US
James GRAZIANO - San Diego CA, US
Helen Hongyuan MAO - San Diego CA, US
Byeong Doo SONG - Chuncheon, KR
Tyson CHASE - San Diego CA, US
Omar BAZIRGAN - San Diego CA, US
International Classification:
C12N 15/10
C07K 16/18
C07K 16/32
C07K 16/28
G01N 33/68
C07K 16/22
Abstract:
Methods for making a combinatorial antibody library from human germline segments are provided. Also provided are libraries of nucleic acid molecules compiled from germline segments encoding VL chains and libraries of nucleic acid molecules encoding VH chains, and resulting antibody libraries. The libraries are provided as addressable libraries. Methods for screening antibody libraries against a target protein antigen, and the identified or selected antibodies are provided.

Antibodies With Ultralong Complementarity Determining Regions

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US Patent:
20160168231, Jun 16, 2016
Filed:
Jul 18, 2014
Appl. No.:
14/905769
Inventors:
- La Jolla CA, US
Omar BAZIRGAN - San Diego CA, US
Assignee:
Fabrus, Inc. - La Jolla CA
International Classification:
C07K 16/10
C07K 14/435
Abstract:
The present disclosure provides antibodies, including antibodies comprising ultralong CDR3 and uses thereof.

Humanized Antibodies

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US Patent:
20150011431, Jan 8, 2015
Filed:
Jan 9, 2013
Appl. No.:
14/371170
Inventors:
- La Jolla CA, US
Omar A. Bazirgan - San Diego CA, US
Hongyuan Helen Mao - San Diego CA, US
International Classification:
C07K 16/46
C07K 14/54
C07K 16/10
C07K 16/00
US Classification:
506 17, 5303873, 536 2353, 4353201, 506 18, 435 696, 506 26, 4352523, 4352351
Abstract:
The present disclosure provides humanized antibodies, including antibodies comprising an ultralong CDR3 (e.g. bovine) and uses thereof.
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Omar Al Bazirgan from Fair Oaks, CA, age ~48 Get Report