US Patent:
20060204958, Sep 14, 2006
Inventors:
Oliver Semmes - Chesapeake VA, US
George Wright - Virginia Beach VA, US
Michael Ward - Chesapeake VA, US
Assignee:
EASTERN VIRGINIA MEDICAL SCHOOL - NORFOLK VA
International Classification:
C12Q 1/70
C12Q 1/68
Abstract:
Protein biomarkers that may advantageously be utilized in aiding in, or making, a diagnosis of HTLV-I-associated myelopathy (HAM), adult T-cell leukemia (ATL) or a negative diagnosis are described. Accordingly, in one aspect of the invention, methods for aiding in, or otherwise making, a diagnosis of ATL, HAM or a negative diagnosis are provided. Methods of detecting the protein biomarkers, kits that may be utilized to detect the biomarkers, as well as isolated protein biomarkers are also provided.