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Olga Lomovskaya Rodny

from Mill Valley, CA
Age ~65

Olga Rodny Phones & Addresses

  • 46 Laverne Ave, Mill Valley, CA 94941 (415) 389-1868
  • Sandpoint, ID
  • Scottsdale, AZ
  • La Jolla, CA
  • 49 Showers Ct, Mountain View, CA 94040 (650) 947-1263
  • San Jose, CA
  • Palo Alto, CA
  • Santa Clara, CA
  • San Diego, CA

Publications

Us Patents

Aerosolized Fluoroquinolones And Uses Thereof

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US Patent:
8357696, Jan 22, 2013
Filed:
Jan 28, 2010
Appl. No.:
12/695981
Inventors:
Mark W. Surber - San Diego CA, US
Keith A. Bostian - Atherton CA, US
Michael N. Dudley - San Diego CA, US
Olga Rodny - Mountain View CA, US
David C. Griffith - San Marcos CA, US
Assignee:
Mpex Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 9/14
A61K 31/00
A61K 31/44
A61K 31/4412
A61K 33/00
A61K 33/06
A61K 33/14
A61K 33/26
A61K 33/30
A01N 25/00
A01N 25/02
A01N 25/06
A01N 59/08
US Classification:
514294, 514279, 424405, 424489, 424602, 424641, 424646, 424677, 424681, 424682
Abstract:
Disclosed herein are formulations of fluoroquinolones suitable for aerosolization and use of such formulations for aerosol administration of fluoroquinolone antimicrobials for the treatment of pulmonary bacterial infections. In particular, inhaled levofloxacin specifically formulated and delivered for bacterial infections of the lungs is described. Methods include inhalation protocols and manufacturing procedures for production and use of the compositions described.

Topical Use Of Levofloxacin For Reducing Lung Inflammation

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US Patent:
8629139, Jan 14, 2014
Filed:
Oct 6, 2009
Appl. No.:
12/574666
Inventors:
Michael N. Dudley - San Diego CA, US
Ruslan Y. Tsivkovski - San Diego CA, US
David C. Griffith - San Marcos CA, US
Olga Rodny - Mountain View CA, US
Assignee:
MPEX Pharmaceuticals, Inc. - Bridgewater NJ
International Classification:
A61K 31/536
C07D 498/14
US Classification:
5142302, 544101
Abstract:
The present invention relates to methods and compositions for the treatment of pulmonary inflammation. In particular, methods and compositions using aerosol levofloxacin or ofloxacin to reduce pulmonary inflammation are provided.

Aerosol Fluoroquinolone Formulations For Improved Pharmacokinetics

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US Patent:
20100087416, Apr 8, 2010
Filed:
Oct 6, 2009
Appl. No.:
12/574680
Inventors:
David C. Griffith - San Marcos CA, US
Michael N. Dudley - San Diego CA, US
Mark W. Surber - San Diego CA, US
Keith A. Bostian - Atherton CA, US
Olga Rodny - Mountain View CA, US
Assignee:
MPEX PHARMACEUTICALS, INC. - San Diego CA
International Classification:
A61K 31/397
A61K 31/535
A61P 11/06
A61P 11/00
US Classification:
51421015, 5142302
Abstract:
The present invention relates to the field of antimicrobial agents. In particular, the present invention relates to the use of aerosolized fluoroquinolones formulated with divalent or trivalent cations and having improved pulmonary availability for the treatment and management of bacterial infections of the lung and upper respiratory tract.

Polybasic Bacterial Efflux Pump Inhibitors And Therapeutic Uses Thereof

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US Patent:
20100152098, Jun 17, 2010
Filed:
Nov 5, 2009
Appl. No.:
12/613329
Inventors:
Tomasz Glinka - Cupertino CA, US
Olga Rodny - Mountain View CA, US
Keith A. Bostian - Atherton CA, US
David M. Wallace - San Diego CA, US
Robert I. Higuchi - Solana Beach CA, US
Chun Chow - San Diego CA, US
Chi Ching Mak - San Diego CA, US
Gavin Hirst - San Diego CA, US
Brian Eastman - San Diego CA, US
Assignee:
Mpex Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 38/05
A61K 38/02
C07D 265/30
C07D 241/42
C07D 215/38
C07D 211/58
C07D 211/06
C07D 213/643
C07D 213/74
C07D 231/12
C07D 209/20
C07D 207/14
C07D 333/24
C07D 321/10
C07D 319/18
C07D 309/10
C07D 307/79
C07C 311/46
C07C 237/20
A61P 31/08
A61P 31/06
A61P 31/04
C07D 217/22
A61K 31/472
US Classification:
514 8, 544166, 544353, 546163, 546171, 546223, 546234, 546291, 546309, 5483771, 548503, 548540, 549 77, 549350, 549362, 549416, 549469, 564 86, 564153, 546143, 514310, 514 19
Abstract:
Disclosed are compounds having polybasic functionalities. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.

Methods Of Treating A Pulmonary Bacterial Infection Using Fluoroquinolones

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US Patent:
20120035166, Feb 9, 2012
Filed:
Oct 21, 2011
Appl. No.:
13/278706
Inventors:
Mike Dudley - San Diego CA, US
David Griffith - San Marcos CA, US
Olga Rodny - Mountain View CA, US
International Classification:
A61K 31/5383
A01N 43/90
A01P 1/00
A61P 31/04
US Classification:
5142302
Abstract:
Disclosed herein are methods of treating a pulmonary bacterial infection comprising bacteria growing under anaerobic conditions using a fluoroquinolone antibiotic. The fluoroquinolone antibiotic may, for example, be levofloxacin or ofloxacin. Also disclosed are methods of inhibiting bacteria growing under anaerobic conditions by exposing the bacteria to an amount of fluoroquinolone antibiotic effective to inhibit growth of said bacteria.

Cyclic Boronic Acid Ester Derivatives And Therapeutic Uses Thereof

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US Patent:
20120040932, Feb 16, 2012
Filed:
Aug 8, 2011
Appl. No.:
13/205112
Inventors:
Gavin Hirst - San Diego CA, US
Raja Reddy - San Diego CA, US
Scott Hecker - Del Mar CA, US
Maxim Totrov - San Diego CA, US
David C. Griffith - San Marcos CA, US
Olga Rodny - Mill Valley CA, US
Michael N. Dudley - San Diego CA, US
Serge Boyer - San Diego CA, US
Assignee:
Rempex Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/69
A61P 31/12
A61P 37/08
A61P 31/04
C07F 5/02
A61P 29/00
A61P 31/10
US Classification:
514 64, 544229, 546 13, 548110, 549 4, 568 6
Abstract:
Disclosed herein are antimicrobial compounds compositions, pharmaceutical compositions, the use and preparation thereof. Some embodiments relate to 1 cyclic boronic acid ester derivatives and their use as therapeutic agents.

Aminoglycoside Derivatives

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US Patent:
20130059808, Mar 7, 2013
Filed:
May 12, 2011
Appl. No.:
13/697302
Inventors:
Tomasz W. Glinka - Cupertino CA, US
Olga Rodny - Mill Valley CA, US
Assignee:
Rempex Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/7028
A61P 31/04
C07H 17/02
A61K 31/7052
C07H 15/12
US Classification:
514 42, 514 43, 536 291, 536 2911
Abstract:
The present invention relates to antimicrobial agents. Some embodiments include compounds, compositions, methods of preparation, and methods of treatment using new aminoglycosides and aminoglycoside derivatives.

Boron Containing Polybasic Bacterial Efflux Pump Inhibitors And Therapeutic Uses Thereof

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US Patent:
20130316943, Nov 28, 2013
Filed:
Feb 6, 2012
Appl. No.:
13/983747
Inventors:
Tomasz Glinka - Cupertino CA, US
Robert Higuchi - Solana Beach CA, US
Scott Hecker - Del Mar CA, US
Brian Eastman - San Diego CA, US
Olga Rodny - Mill Valley CA, US
Assignee:
REMPEX PHARMACEUTICALS, INC. - San Diego CA
International Classification:
C07K 5/06
A61K 38/05
US Classification:
514 31, 558288, 514 24, 562 7, 546 13, 548405, 536 168, 544 582
Abstract:
Disclosed herein are polybasic bacterial efflux pump inhibitors containing boronic acid functionality and their methods of synthesis, methods of use, and pharmaceutical compositions. Some embodiments include methods of treating or preventing a bacterial infection by co-administering to a subject infected with bacteria or at risk of infection with bacteria the efflux pump inhibitor with another anti-bacterial agent.
Olga Lomovskaya Rodny from Mill Valley, CA, age ~65 Get Report