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Nozer M Mehta

from Belmar, NJ
Age ~77
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Also known as:
Nozer N Mehta, Mazur M Mehta, Nally N Mehta, Nelly N Mehta, Noyer Mehta, Mehta Mehta Mozer, Noier Mehta, Mozer Mehta Mehta, Mehta Mazur, Mehta Noyer
Related to:
Catherine M Gettler, 71Firoze N Mehta, 40Persis K Mehta, 42Nelly N Mehta, 79
Connected to:
Aarya H Mehta, 29Amber R Mehta, 54Ami H Mehta, 55Amrish Mehta, 37Anesh K Mehta, 52Ankesh Mehta, 47Ankita N Mehta, 47Anne Mehta, 37Anvi S Mehta, 41Arjit Mehta, 37

Nozer Mehta Phones & Addresses

  • Belmar, NJ
  • Red Bank, NJ
  • 14 Old Coach Rd, Randolph, NJ 07869 (973) 895-4844
  • Clifton, NJ
  • Rockaway, NJ

Work

Company: Nmm Address: 14 Old Coach Road, Rockaway, NJ 07866 Phones: (973) 895-4844 Position: Founder Industries: Engineering Services

Resumes

Resumes

Nozer Mehta Photo 1

Chief Scientific Officer At Enteris Biopharma, Inc.

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Position:
Chief Scientific Officer at Enteris BioPharma, Inc.
Location:
Greater New York City Area
Industry:
Biotechnology
Work:
Enteris BioPharma, Inc. since Jul 2013
Chief Scientific Officer
Unigene Labs Inc Jun 2012 - Jun 2013
Chief Scientific Officer
Unigene Laboratories Inc. 2005 - Jul 2012
VP, Biological R&D

Business Records

Name / Title
Company / Classification
Phones & Addresses
Nozer Mehta
Founder
Nmm
Engineering Services
14 Old Coach Road, Rockaway, NJ 07866
Nozer Mehta
Principal
Enteris BioPharma, Inc.
Biotechnology · Mfg Pharmaceutical Preparations · Pharmaceutical Preparations
83 Fulton St, Boonton, NJ 07005
Nozer M. Mehta
Vp Biological Research And Development
Unigene Laboratories, Inc
Noncommercial Research Organization Commercial Physical Research · Research & Development in Biotechnology · Laboratories-Research & Develo
110 Little Fls Rd, Fairfield, NJ 07004
(973) 882-0860, (973) 882-8277, (973) 227-6088
Nozer Mehta
Founder
Nmm
Engineering Services
14 Old Coach Road, Rockaway, NJ 07866

Publications

Us Patents

Direct Expression Of Peptides Into Culture Media

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US Patent:
6627438, Sep 30, 2003
Filed:
Feb 9, 2001
Appl. No.:
09/780878
Inventors:
Nozer M. Mehta - Randolph NJ
Angelo P. Consalvo - Monroe NY
Martha V. L. Ray - Nutley NJ
Christopher P. Meenan - Lincoln Park NJ
Assignee:
Unigene Laboratories Inc. - Fairfield NJ
International Classification:
C12P 2106
US Classification:
4353201, 4352523, 435 694, 43525233, 435 691, 530399, 530300, 530412, 530416, 536 231, 536 241
Abstract:
Expression systems are disclosed for the direct expression of peptide products into the culture media where genetically engineered host cells are grown. High yield was achieved with novel vectors, a special selection of hosts, and/or fermentation processes which include careful control of cell growth rate, and use of an inducer during growth phase. Special vectors are provided which include control regions having multiple promoters linked operably with coding regions encoding a signal peptide upstream from a coding region encoding the peptide of interest. Multiple transcription cassettes are also used to increase yield. The production of amidated peptides using the expression systems is also disclosed.

Oral Delivery Of Peptides Using Enzyme-Cleavable Membrane Translocators

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US Patent:
6673574, Jan 6, 2004
Filed:
Nov 29, 2001
Appl. No.:
09/997465
Inventors:
William Stern - Tenafly NJ
Nozer M. Mehta - Randolph NJ
Martha V. L. Ray - Nutley NJ
Assignee:
Unigene Laboratories Inc. - Fairfield NJ
International Classification:
C12P 2104
US Classification:
435 697, 435183, 5303873, 4241841, 4241921, 4241931
Abstract:
Bioavailability of peptide active agents to be administered orally is enhanced by a pharmaceutical composition providing targeted release of the peptide to the intestine in addition to having the active peptide linked to a membrane translocator which is capable of being at least partially cleaved in vivo by an enzyme. The composition includes an acid-resistant protective vehicle which transports components of the invention through the stomach and a sufficient amount of a pH-lowering agent to lower local intestinal pH. All components are released together into the intestine with the peptide.

Direct Expression Of Peptides Into Culture Media

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US Patent:
6737250, May 18, 2004
Filed:
Feb 9, 2001
Appl. No.:
09/780643
Inventors:
Nozer M. Mehta - Randolph NJ
Angelo P. Consalvo - Monroe NY
Martha V. L. Ray - Nutley NJ
Christopher P. Meenan - Lincoln Park NJ
Assignee:
Unigene Laboratories, Inc. - Fairfield NJ
International Classification:
C07K 100
US Classification:
435 691, 4353201, 4352523, 435 694, 43525233, 530399, 530300, 530412, 530416
Abstract:
Expression systems are disclosed for the direct expression of peptide products into the culture media where genetically engineered host cells are grown. High yield was achieved with novel vectors, a special selection of hosts, and/or fermentation processes which include careful control of cell growth rate, and use of an inducer during growth phase. Special vectors are provided which include control regions having multiple promoters linked operably with coding regions encoding a signal peptide upstream from a coding region encoding the peptide of interest. Multiple transcription cassettes are also used to increase yield. The production of amidated peptides using the expression systems is also disclosed.

Enzymatic Reactions In The Presence Of Keto Acids

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US Patent:
7445911, Nov 4, 2008
Filed:
Nov 22, 2005
Appl. No.:
11/285136
Inventors:
Angelo P. Consalvo - Monroe NY, US
Nozer M. Mehta - Randolph NJ, US
William Stern - Tenafly NJ, US
James P. Gilligan - Union NJ, US
Assignee:
Unigene Laboratories Inc. - Fairfield NJ
International Classification:
C12P 21/06
US Classification:
435 681
Abstract:
Conversion in vitro of X-Gly to X-alpha-hydroxy-Gly or X—NH(X being a peptide or any other compound having a carbonyl group capable of forming a covalent bond with glycine) is accomplished enzymatically in the presence of keto acids, or salts or esters thereof, to provide a good yield without the necessity of catalase or similar enzymatic reaction enhancers. Peptidylglycine α-amidating monooxygenase (PAM) is a preferred enzyme for catalyzing the conversion. Alternatively, peptidylglycine α-hydroxylating monooxygenase (PHM) is utilized to convert X-Gly to X-alpha-hydroxy-Gly which may be recovered, or optionally may be simultaneously or sequentially converted to an amide by either a Lewis base or action of the enzyme peptidyl α-hydroxyglycine α-amidating lyase (PAL). Both PHM and PAL are functional domains of PAM.

Method For Fostering Bone Formation And Preservation

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US Patent:
7531518, May 12, 2009
Filed:
May 11, 2005
Appl. No.:
11/128095
Inventors:
Agnès Vignery - Branford CT, US
Nozer M. Mehta - Randolph NJ, US
James P. Gilligan - Union NJ, US
Assignee:
Unigene Laboratories Inc. - Boonton NJ
Yale University - New Haven CT
International Classification:
A61K 38/00
A61F 2/02
A61F 2/44
US Classification:
514 21, 435810, 623 1111, 623 1312, 623 1717
Abstract:
A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.

Bacterial Host Cell For The Direct Expression Of Peptides

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US Patent:
7541174, Jun 2, 2009
Filed:
Oct 30, 2007
Appl. No.:
11/929028
Inventors:
Nozer M. Mehta - Randolph NJ, US
Angelo P. Consalvo - Monroe NY, US
Martha V. L. Ray - Nutley NJ, US
Christopher P. Meenan - Lincoln Park NJ, US
Assignee:
Unigene Laboratories Inc. - Boonton NJ
International Classification:
C12N 1/20
C12N 15/00
US Classification:
43525233, 4352521, 4353201
Abstract:
Expression systems are disclosed for the direct expression of peptide products into the culture media where genetically engineered host cells are grown. High yield was achieved with a special selection of hosts, and/or fermentation processes which include careful control of cell growth rate, and use of an inducer during growth phase. Special universal cloning vectors are provided for the preparation of expression vectors which include control regions having multiple promoters linked operably with coding regions encoding a signal peptide upstream from a coding region encoding the peptide of interest. Multiple transcription cassettes are also used to increase yield. The production of amidated peptides using the expression systems is also disclosed.

Bacterial Host Cell For The Direct Expression Of Peptides

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US Patent:
7553655, Jun 30, 2009
Filed:
Oct 30, 2007
Appl. No.:
11/929079
Inventors:
Nozer M. Mehta - Randolph NJ, US
Angelo P. Consalvo - Monroe NY, US
Martha V. L. Ray - Nutley NJ, US
Christopher P. Meenan - Lincoln Park NJ, US
Assignee:
Unigene Laboratories Inc. - Boonton NJ
International Classification:
C12N 1/20
C12N 15/00
US Classification:
43525233, 4352521, 4353201
Abstract:
Expression systems are disclosed for the direct expression of peptide products into the culture media where genetically engineered host cells are grown. High yield was achieved with a special selection of hosts, and/or fermentation processes which include careful control of cell growth rate, and use of an inducer during growth phase. Special universal cloning vectors are provided for the preparation of expression vectors which include control regions having multiple promoters linked operably with coding regions encoding a signal peptide upstream from a coding region encoding the peptide of interest. Multiple transcription cassettes are also used to increase yield. The production of amidated peptides using the expression systems is also disclosed.

Method For Fostering Bone Formation And Preservation

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US Patent:
7648700, Jan 19, 2010
Filed:
Aug 16, 2007
Appl. No.:
11/839957
Inventors:
Agnes Vignery - Branford CT, US
Nozer M. Mehta - Randolph NJ, US
James P. Gilligan - Union NJ, US
Assignee:
Unigene Laboratories, Inc. - Boonton NJ
Yale University - New Haven CT
International Classification:
A01N 63/00
A61K 38/00
A61F 2/02
US Classification:
424 937, 514 12, 623 1111, 623 1312, 623 1717
Abstract:
A method of inducing bone formation in a subject in need of such inducement comprises the steps of mechanically inducing an increase in osteoblast activity in the subject and elevating blood concentration of at least one bone anabolic agent in the subject. The method steps may be performed in any order, but in sufficient time proximity that the elevated concentration of the anabolic agent and the mechanically induced increase in osteoblast activity overlaps. The method may additionally comprise providing the subject with an elevated blood concentration of at least one antiresorptive agent, wherein the elevated concentration is sufficient to prevent resorption of new bone growth produced due to the osteoblast activity. Use of the method permits targeting of specific bones of the subject for bone production and preservation, faster bone production and earlier discontinuation of bone anabolic pharmaceuticals. Kits adapted for performing the method are provided.
Control profile
Nozer M Mehta from Belmar, NJ, age ~77 Get Report