US Patent:
20120302427, Nov 29, 2012
Inventors:
Noha Elmouelhi - Randolph NJ, US
Kevin Cooper - Flemington NJ, US
Sriram Natarajan - Bridgewater NJ, US
Hong Yee Low - Botannia, SG
Isabel Rodriguez - Singapore, SG
Emma Kim Luong-Van - Singapore, SG
Assignee:
ADVANCED TECHNOLOGIES & REGENERATIVE MEDICINE, LLC - Raynham MA
International Classification:
B01J 20/28
B01J 20/30
Abstract:
A biologic-adsorbent, e.g., protein-adsorbent, material is prepared by forming a polymeric substrate into structures having high surface area topography whose biologic adsorbing properties can be controlled. Biologic adsorption by these structures of optimized high surface area topography is increased by mild treating of the surfaces, e.g., by oxygen plasma, without substantially altering topography. Structures can have tailored geometric features including microstructures, e.g., pillars, with a diameter from 100 nm-50 μm and height greater than 1 μm.