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Nnochiri M Ekwuribe

from Cary, NC
Age ~69
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Also known as:
Ngozi M Ekwuribe, Ngozi N Ekwuribe, Nnochiri N Ekwuribe, Nnochiri O Ekwuribe, Nnoc Ekwuribe, I Ekwuribe, H Ekwuribe, Ngozi E, Nochiri Ekwuribe, Onyemechi Ekwuribe
Phone and address:
216 Coltsgate Dr, Cary, NC 27518
(919) 233-1163
Related to:
Kingsley U Okoroafor, 61Onyemechi Chukuma Ekwuribe, 45Chinwe Ekwuribe, 31Ebere EkwuribeChinyere Okoroafor, 47Nedum Ekwuribe, 46Chinyere A Ekwuribe, 47Chi A Okoroafor, 48
Connected to:
Dimitry Ekzarkhov, 54Aaron S El, 75Ashry M El, 38Benjamin R El, 81Chami Y El, 75Denise G El, 74Don N El, 62Dora A El, 66Eddie D El, 117Edwin B El, 73

Nnochiri Ekwuribe Phones & Addresses

  • 216 Coltsgate Dr, Cary, NC 27518 (919) 233-1163 (919) 816-8633
  • Durham, NC
  • Raleigh, NC
  • Southfield, MI
  • Columbus, OH
  • Detroit, MI
  • Tampa, FL
  • 216 Coltsgate Dr, Cary, NC 27518 (919) 244-8743

Work

Position: Sales Occupations

Publications

Us Patents

Taxane Prodrugs

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US Patent:
6380405, Apr 30, 2002
Filed:
Dec 31, 1999
Appl. No.:
09/476974
Inventors:
Nnochiri Ekwuribe - Cary NC
Gary S. Bartley - Durham NC
Christopher H. Price - Chapel Hill NC
Assignee:
Nobex Corporation - Research Triangle Park NC
International Classification:
C07D30514
US Classification:
549510, 549511, 514449
Abstract:
The present invention generally provides taxane prodrugs comprising at least one taxane joined by hydrolyzable bond(s) to one or more polyethylene glycol oligomer(s) selected from the group consisting of a straight or branched polyethylene glycol oligomer having from 1 to 25 polyethylene glycol units and optionally comprising a salt-forming moiety. The polyethylene glycol oligomer preferably comprises a salt-forming moiety, which is preferably selected from the group consisting of ammonium and carboxylate.

6-Methoxy-2-Naphthylacetic Acid Prodrugs

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US Patent:
6436990, Aug 20, 2002
Filed:
Oct 27, 2000
Appl. No.:
09/698594
Inventors:
Nnochiri Nkem Ekwuribe - Cary NC
Jennifer A. Riggs - Raleigh NC
Assignee:
Nobex Corporation - Durham NC
International Classification:
A61K 31235
US Classification:
514532, 514543
Abstract:
The present invention provides compositions useful for the treatment of inflammation in humans, and related methods of treatment for the same. In one embodiment the composition is In another embodiment, the composition is In yet another embodiment, the composition is Additional alternative embodiments are R or Râ that are therapeutic moieties.

5-Asa Derivatives Having Anti-Inflammatory And Antibiotic Activity And Methods Of Treating Diseases Therewith

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US Patent:
6458776, Oct 1, 2002
Filed:
Aug 29, 2001
Appl. No.:
09/942510
Inventors:
Nnochiri Nkem Ekwuribe - Cary NC
Jennifer A. Riggs-Sauthier - Raleigh NC
Elizabeth Malson - Burbank CA
Assignee:
Nobex Corporation - Durham NC
International Classification:
A61K 31655
US Classification:
514150, 534660
Abstract:
Compounds are disclosed represented by the following formula: where R is a substituted or unsubstituted phenyl group, and where Z is selected such that a compound, Z-R -NH , formed by cleavage of the azo bond is a non-absorbable antibiotic; or an ester or pharmacologically acceptable salt of the compound of Formula I. Compounds of the present invention may be utilized for the prophylaxis or treatment of various diseases including, but not limited to, intestinal diseases such as inflammatory bowel disease and/or travelers diarrhea, liver diseases such as hepatic encephalopathy, and/or diseases treatable by a non-absorbable antibiotic.

Methods Of Synthesizing Acylanilides Including Bicalutamide And Derivatives Thereof

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US Patent:
6479692, Nov 12, 2002
Filed:
May 2, 2001
Appl. No.:
09/847229
Inventors:
Nnochiri N. Ekwuribe - Cary NC
Assignee:
Nobex Corporation - Durham NC
International Classification:
C07C25550
US Classification:
558413
Abstract:
Methods of synthesizing an acylanilide.

6-Methoxy-2-Naphthylacetic Acid Prodrugs

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US Patent:
6525098, Feb 25, 2003
Filed:
Oct 27, 2000
Appl. No.:
09/697795
Inventors:
Nnochiri Nkem Ekwuribe - Cary NC
Tatyana A. Dyakonov - Greensboro NC
Assignee:
Nobex Corporation - Durham NC
International Classification:
A61K 3119
US Classification:
514569, 514682, 514732
Abstract:
The present invention provides therapeutically effective amounts of 6MNA prodrugs. The pharmaceutical composition comprises wherein R is H or CORâ, wherein Râ is selected from the group consisting of C to C alkyl, (CH ) O(CH ) , (CH ) (OC H ) O(CH ) , (CH ) (OC H ) , (OCH H ) ONO and (OCH H ) O(CH ) wherein m is an integer from 2 to 4, and n and p are integers from 1 to 4. Alternatively, R is a therapeutic moiety.

Taxane Prodrugs

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US Patent:
6541508, Apr 1, 2003
Filed:
Mar 9, 2001
Appl. No.:
09/802739
Inventors:
Nnochiri N. Ekwuribe - Cary NC
Christopher H. Price - Chapel Hill NC
Gary S. Bartley - Florence SC
Assignee:
Nobex Corporation - Durham NC
International Classification:
A61K 31337
US Classification:
514449, 549510, 549511, 528421
Abstract:
Taxane prodrugs comprise a taxane joined by a hydrolyzable bond to one or more oligomers that comprise a polyethylene glycol moiety. The oligomer preferably further comprises a salt-forming moiety.

6-Methoxy-2-Naphthylacetic Acid Prodrugs

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US Patent:
6552078, Apr 22, 2003
Filed:
Mar 30, 2001
Appl. No.:
09/823000
Inventors:
Nnochiri Nkem Ekwuribe - Cary NC, 27511
Jennifer A. Riggs-Sauthier - Raleigh NC, 27612
International Classification:
A61K 3124
US Classification:
514534
Abstract:
The present invention provides compositions useful for the treatment of inflammation in humans, and related methods of treatment for the same. In one embodiment the composition is In another embodiment, the composition is In yet another embodiment, the composition is Additional alternative embodiments are R or Râ are therapeutic moieties.

Immunoregulatory Compounds And Derivatives And Methods Of Treating Diseases Therewith

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US Patent:
6583128, Jun 24, 2003
Filed:
Aug 29, 2001
Appl. No.:
09/942464
Inventors:
Nnochiri Nkem Ekwuribe - Cary NC
Jennifer A. Riggs-Sauthier - Raleigh NC
Assignee:
Nobex Corporation - Durham NC
International Classification:
A61K 31655
US Classification:
514150, 534660, 534852, 534853
Abstract:
Compounds are disclosed having the structure of Formula I: where R , R , and R are independently hydrogen or C to C alkyl, and R is: where R is selected from the group consisting of hydrogen and C to C alkyl, or where R , R and R are independently hydrogen or C to C alkyl; or the esters or pharmacologically acceptable salts thereof. Such compounds may be utilized for the prophylaxis or treatment of various diseases, particularly inflammatory conditions of the GI tract. Methods of treating inflammatory conditions of the GI tract such as inflammatory bowel disease using compounds having the following formula are also disclosed: where R , R and R are independently selected from the group consisting of hydrogen and C to C alkyl, and R is selected from the group consisting of hydrogen and âC(O)R , where R is a C to C alkyl or an aryl group.
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Nnochiri M Ekwuribe from Cary, NC, age ~69 Get Report