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Nicholas J Laping

from Wilmington, DE
Age ~64
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Also known as:
Nick Laping, Ping Nicholas La, Ping Carole La
Related to:
Margaret M Mcbeth, 86Karen M Laping, 58Hans J LapingKarl H Laping, 92Hans N Laping, 59Karl H Laping, 75Carole J Laping, 64Ilse R Laping, 92
Connected to:
Catherine L Laping, 76Glorianne R Laping, 51Lindsay N Laping, 37Sarah L Laping, 38Jamie O Lapington, 45Irma M Lapinid, 79Rosemarie R Lapinid, 68Barbara D Lapins, 84Peter A Lapins, 57Alicia Lapinski, 72

Nicholas Laping Phones & Addresses

  • Wilmington, DE
  • 1105 Amalfi Dr, West Chester, PA 19380 (610) 701-4232
  • 1323 Dunsinane Dr, West Chester, PA 19380
  • King of Prussia, PA
  • Pasadena, CA
  • Los Angeles, CA
  • 1105 Amalfi Dr, West Chester, PA 19380

Work

Company: Endo pharmaceuticals Feb 2009 Position: Director

Education

Degree: Ph.D. School / High School: University of Illinois at Urbana-Champaign 1983 to 1989 Specialities: Physiology

Skills

Clinical Development • Biotechnology • Oncology • Pharmacology • Drug Discovery • Molecular Biology

Industries

Pharmaceuticals

Resumes

Resumes

Nicholas Laping Photo 1

Director At Endo Pharmaceuticals

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Position:
Director at Endo Pharmaceuticals
Location:
Greater Philadelphia Area
Industry:
Pharmaceuticals
Work:
Endo Pharmaceuticals since Feb 2009
Director
The Medialytic Group Oct 2008 - Feb 2009
Scientific Consultant
GlaxoSmithKline Mar 2004 - Aug 2008
Director of Biology
GlaxoSmithKline Mar 2000 - Mar 2004
Manager
SmithKline Beecham Jun 1994 - Mar 2000
Investigator/Senior Investigator
Education:
University of Illinois at Urbana-Champaign 1983 - 1989
Ph.D., Physiology University of Illinois at Urbana-Champaign 1979 - 1983
BS, Biology
Skills:
Clinical Development
Biotechnology
Oncology
Pharmacology
Drug Discovery
Molecular Biology

Publications

Us Patents

Human Mad Proteins And Uses Thereof

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US Patent:
20020025558, Feb 28, 2002
Filed:
Aug 15, 2001
Appl. No.:
09/930317
Inventors:
Nicholas Laping - West Chester PA, US
International Classification:
C12P021/02
C12N005/06
G01N033/53
C07H021/04
A61K038/43
C12N009/99
C12N009/64
US Classification:
435/069100, 435/184000, 435/226000, 435/320100, 435/325000, 536/023200, 424/094100, 435/007100
Abstract:
Human MADr3 or MADr4 polypeptides and DNA (RNA) encoding such MADr3 or MADr4 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such MADr3 or MADr4, or compounds which inhibit or stimulate MADr3 or MADr4 for stimulating wound healing, and treating cancers, among others, are also disclosed. Agonist and antagonists of these MAD proteins and methods of their use are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the MADr3 or MADr4 and for detecting altered levels of the polypeptide in a host.

Method Of Treatment

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US Patent:
20090281110, Nov 12, 2009
Filed:
Jun 22, 2007
Appl. No.:
12/306024
Inventors:
Jakob Busch-Petersen - King of Prussia PA, US
Jeffery D. Bray - King of Prussia PA, US
Nicholas J. Laping - King of Prussia PA, US
Eugene T. Grygielko - King of Prussia PA, US
Richard M. Goodman - King of Prussia PA, US
International Classification:
A61K 31/495
US Classification:
51425212
Abstract:
This invention relates to the use of sulfonamide substituted diphenyl urea compounds to treat endometriosis.

Use Of Aminoindane Compounds In Treating Overactive Bladder And Interstitial Cystitis

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US Patent:
20140051702, Feb 20, 2014
Filed:
Aug 15, 2013
Appl. No.:
13/967389
Inventors:
Tony Priestley - West Chester PA, US
Nicholas James Laping - Malvern PA, US
Assignee:
Endo Pharmaceuticals Inc. - Malvern PA
International Classification:
A61K 31/5386
C07D 211/26
A61K 31/40
C07D 207/09
A61K 31/435
C07D 471/10
A61K 31/4545
C07D 401/12
A61K 31/506
A61K 31/454
C07D 417/12
C07D 498/10
A61K 31/453
C07D 405/12
A61K 31/452
US Classification:
5142355, 514319, 514408, 514278, 514318, 514275, 514321
Abstract:
The present application provides methods of using the aminoindane compounds of formula (I) or (II) in treating an overactive bladder or interstitial cystitis by administering one or more of the compounds to a patient.

Human Mad Proteins And Uses Thereof

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US Patent:
63098563, Oct 30, 2001
Filed:
Oct 30, 1998
Appl. No.:
9/183228
Inventors:
Nicholas J. Laping - West Chester PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12N 1500
US Classification:
435 691
Abstract:
Human MADr3 or MADr4 polypeptides and DNA (RNA) encoding such MADr3 or MADr4 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such MADr3 or MADr4, or compounds which inhibit or stimulate MADr3 or MADr4 for stimulating wound healing, and treating cancers, among others, are also disclosed. Agonist and antagonists of these MAD proteins and methods of their use are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the MADr3 or MADr4 and for detecting altered levels of the polypeptide in a host.

Crfg-1B, A Target And Marker For Chronic Renal Failure

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US Patent:
62554719, Jul 3, 2001
Filed:
Feb 9, 1998
Appl. No.:
9/020465
Inventors:
Nicholas J Laping - West Chester PA
Barbara Olson - Norristown PA
Yuan Zhu - Blue Bell PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07H 2104
C12P 2106
C12P 1934
C12N 120
C12N 1563
US Classification:
536 235
Abstract:
CRFG-1b polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CRFG-1b polypeptides and polynucleotides in the design of protocols for the treatment of chronic renal disease, renal ischemia, diabetic nephropathy, acute renal failure, neurodegenerative disease, and Alzheimer's disease, among others, and diagnostic assays for such conditions.

Crfg-1A, A Target And Marker For Chronic Renal Failure

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US Patent:
58799087, Mar 9, 1999
Filed:
Feb 9, 1998
Appl. No.:
/020466
Inventors:
Nicholas J Laping - West Chester PA
Barbara Olson - Norristown PA
Yuan Zhu - Blue Bell PA
Assignee:
Smithkline Beecham Corporation - Philadelphia PA
International Classification:
C12P 2106
C12N 120
C12N 1500
C07H 1700
US Classification:
435 691
Abstract:
CRFG-1a polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CRFG-1a polypeptides and polynucleotides in the design of protocols for the treatment of chronic renal disease, renal ischemia, diabetic nephropathy, acute renal failure, Neurodegenerative disease, and Alzheimer's disease, among others, and diagnostic assays for such conditions.

Crfg-1A, A Target And Marker For Chronic Renal Failure

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US Patent:
61275220, Oct 3, 2000
Filed:
Nov 16, 1998
Appl. No.:
9/192659
Inventors:
Nicholas J Laping - West Chester PA
Barbara Olson - Norristown PA
Yuan Zhu - Blue Bell PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07K 1400
US Classification:
530350
Abstract:
CRFG-1a polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing CRFG-1a polypeptides and polynucleotides in the design of protocols for the treatment of chronic renal disease, renal ischemia, diabetic nephropathy, acute renal failure, Neurodegenerative disease, and Alzeimer's disease, among others, and diagnostic assays for such conditions.

Dna Encoding Human Mad Proteins

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US Patent:
58666931, Feb 2, 1999
Filed:
Oct 16, 1996
Appl. No.:
8/732028
Inventors:
Nicholas J. Laping - West Chester PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07H 2104
US Classification:
536 231
Abstract:
Human MADr3 or MADr4 polypeptides and DNA (RNA) encoding such MADr3 or MADr4 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such MADr3 or MADr4, or compounds which inhibit or stimulate MADr3 or MADr4 for stimulating wound healing, and treating cancers, among others, are also disclosed. Agonist and antagonists of these MAD proteins and methods of their use are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the MADr3 or MADr4 and for detecting altered levels of the polypeptide in a host.
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Nicholas J Laping from Wilmington, DE, age ~64 Get Report