US Patent:
20110275625, Nov 10, 2011
Inventors:
Neil Alexander Farrow - Ridgefield CT, US
Donghong Amy Gao - Hopewell Junction NY, US
Alexander Heim-Riether - Biberach an der Riss, DE
Shuang Liang - Danbury CT, US
Sabine Schlyer - New Milford CT, US
Lana Louise Smith Keenan - Poughquag NY, US
Steven John Taylor - Southbury CT, US
Bernd Wellenzohn - Langenargen, DE
Dieter Wiedenmayer - Biberach, DE
Zhaoming Xiong - Brookfield CT, US
Qiang Zhang - Woodbury CT, US
Assignee:
BOEHRINGER INGELHEIM INTERNATIONAL GMBH - Ingelheim am Rhein
International Classification:
A61K 31/444
C07D 405/04
A61K 31/443
A61K 31/4433
C07D 401/12
A61K 31/4439
C07D 401/14
A61K 31/4178
C07D 407/12
A61K 31/341
C07D 471/04
A61K 31/437
A61K 31/506
A61K 31/497
A61K 31/501
C07D 413/12
A61K 31/5377
A61P 29/00
A61P 19/10
A61P 9/10
A61P 9/00
A61P 25/00
A61P 35/00
C07D 405/14
US Classification:
5142315, 546261, 514333, 5462847, 514336, 5462821, 514337, 5462841, 5462751, 514341, 5462754, 5483154, 514397, 549473, 514471, 546121, 514300, 544333, 514256, 544405, 51425505, 544238, 51425201, 544152
Abstract:
Disclosed are compounds and compositions of the formula (I) as described herein which are inhibitors of MMP-13. Also disclosed are methods of using and making compounds of the formula (I).