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Natalie Fursov

from Harleysville, PA
Age ~54

Natalie Fursov Phones & Addresses

  • 280 Manor Rd, Harleysville, PA 19438 (215) 256-1406
  • 288 Manor Rd, Harleysville, PA 19438 (215) 256-1406
  • Lower Salford, PA
  • Norristown, PA
  • New York, NY
  • Piscataway, NJ
  • Montgomery, PA

Publications

Us Patents

Macaca Fascicularis St2L

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US Patent:
20100247442, Sep 30, 2010
Filed:
Mar 31, 2009
Appl. No.:
12/415095
Inventors:
Adam Cotty - Radnor PA, US
Natalie Fursov - Radnor PA, US
Michael Naso - Radnor PA, US
International Classification:
A61K 49/00
C07H 21/00
C12N 15/63
C12N 5/00
C07K 14/00
C12P 21/00
C07K 16/00
G01N 33/53
C12Q 1/02
C12Q 1/68
US Classification:
424 92, 536 235, 4353201, 435325, 530350, 435 691, 5303879, 436501, 435 29, 435 6
Abstract:
Isolated polynucleotides encoding ST2L (Cyno ST2L), polypeptides obtainable from expression of these polynucleotides, recombinant cells, and methods of use are disclosed.

St2L Antagonists And Methods Of Use

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US Patent:
20130287777, Oct 31, 2013
Filed:
Mar 13, 2013
Appl. No.:
13/798226
Inventors:
Karen Duffy - Spring House PA, US
Natalie Fursov - Spring House PA, US
LeRoy Hall - Raritan NJ, US
Catherine Healy - Spring House PA, US
Roberta Lamb - Spring House PA, US
Jinquan Luo - Spring House PA, US
Ravi Malaviya - Spring House PA, US
Michael Naso - Spring House PA, US
Michael Pratta - Spring House PA, US
Mark Tornetta - Spring House PA, US
John Wheeler - Spring House PA, US
Assignee:
JANSSEN BIOTECH, INC. - Horsham PA
International Classification:
C07K 16/28
US Classification:
4241361, 4241331, 4241391
Abstract:
The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.

St2L Antagonists And Methods Of Use

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US Patent:
20130336980, Dec 19, 2013
Filed:
Mar 13, 2013
Appl. No.:
13/798204
Inventors:
Natalie Fursov - Spring House PA, US
LeRoy Hall - Raritan NJ, US
Catherine Healy - Spring House PA, US
Roberta Lamb - Spring House PA, US
Jinquan Luo - Spring House PA, US
Ravi Malaviya - Spring House PA, US
Michael Naso - Spring House PA, US
Michael Pratta - Mulica Hill NJ, US
Mark Tornetta - Spring House PA, US
John Wheeler - Spring House PA, US
Assignee:
JANSSEN BIOTECH, INC. - Horsham PA
International Classification:
C07K 16/28
US Classification:
4241361, 5303879, 536 2353, 4353201, 435 696, 4241391, 4241721, 435419, 4352523, 435331
Abstract:
The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.

Human Anti-Cd27 Antibodies

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US Patent:
20200277393, Sep 3, 2020
Filed:
May 19, 2020
Appl. No.:
16/878209
Inventors:
- Horsham PA, US
Johan Fransson - Toronto, CA
Natalie Fursov - Harleysville PA, US
Damon Hamel - San Diego CA, US
Thomas Malia - Philadelphia PA, US
Galina Obmolova - Phoenixville PA, US
Tatiana Ort - Plymouth Meeting PA, US
Michael Rycyzyn - Berwyn PA, US
Michael Scully - Medford NJ, US
Raymond Sweet - Bryn Mawr PA, US
Alexey Teplyakov - Phoenixville PA, US
John Wheeler - Devon PA, US
Juan Carlos Almagro - Brookline MA, US
International Classification:
C07K 16/28
Abstract:
Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions.

Methods Of Inhibiting Activity Using Anti-Cd27 Antibodies

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US Patent:
20190248910, Aug 15, 2019
Filed:
Apr 12, 2019
Appl. No.:
16/382645
Inventors:
- Horsham PA, US
Johan Fransson - Toronto, CA
Natalie Fursov - Harleysville PA, US
Damon Hamel - San Diego CA, US
Thomas Malia - Philadelphia PA, US
Galina Obmolova - Phoenixville PA, US
Tatiana Ort - Plymouth Meeting PA, US
Michael Rycyzyn - Berwyn PA, US
Michael Scully - Medford NJ, US
Raymond Sweet - Bryn Mawr PA, US
Alexey Teplyakov - Phoenixville PA, US
John Wheeler - Devon PA, US
Juan Carlos Almagro - Brookline MA, US
International Classification:
C07K 16/28
Abstract:
Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions.

Methods Of Inhibiting Activity Using Anti-Cd27 Antibodies

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US Patent:
20170320957, Nov 9, 2017
Filed:
May 16, 2017
Appl. No.:
15/596609
Inventors:
- Horsham PA, US
Johan Fransson - Toronto, CA
Natalie Fursov - Harleysville PA, US
Damon Hamel - San Diego CA, US
Thomas Malia - Philadelphia PA, US
Galina Obmolova - Phoenixville PA, US
Tatiana Ort - Plymouth Meeting PA, US
Michael Rycyzyn - Berwyn PA, US
Michael Scully - Medford NJ, US
Raymond Sweet - Bryn Mawr PA, US
Alexey Teplyakov - Phoenixville PA, US
John Wheeler - Devon PA, US
Juan Carlos Almagro - Brookline MA, US
International Classification:
C07K 16/28
C07K 16/28
A61K 39/00
Abstract:
Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions.

St2L Antagonists And Methods Of Use

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US Patent:
20170066831, Mar 9, 2017
Filed:
Nov 12, 2015
Appl. No.:
14/939624
Inventors:
- Horsham PA, US
Natalie Fursov - Harleysville PA, US
LeRoy Hall - Raritan NJ, US
Catherine Healy - Spring House PA, US
Roberta Lamb - Wynnewood PA, US
Jinquan Luo - Malvern PA, US
Ravi Malaviya - Spring House PA, US
Michael Naso - Spring House PA, US
Michael Pratta - Mulica Hill NJ, US
Mark Tornetta - Collegeville PA, US
John Wheeler - Devon PA, US
Sheng-Jiun Wu - Broomall PA, US
International Classification:
C07K 16/28
Abstract:
The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.
Natalie Fursov from Harleysville, PA, age ~54 Get Report