Inventors:
Naoto Izawa - Princeton NJ, US
Norie Satoh - Shizuoka, JP
Nobuhiro Yagi - Shizuoka, JP
Kazue Ouchi - Shizuoka, JP
Shoichi Narita - Shizuoka, JP
Noboru Aoki - Shizuoka, JP
Assignee:
Koyowa Hakko Kogyo Co. Ltd. - Tokyo
International Classification:
A61K 31/381
C07D 495/02
Abstract:
The present invention provides microcrystals of (S)-(+)-3,3,3-trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propaneamide represented by the following formula which has an average particle size of 80 μm or less, a pharmaceutical formulation comprising the microcrystals, and the like.