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Naing A Aay

from San Mateo, CA
Age ~62
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Also known as:
Naing A Kim
Phone and address:
112 N Rochester St, San Mateo, CA 94401
(650) 343-5454
Related to:
Angelo J Cabalquinto, 35Hae S Kim, 46Joyce M Kim, 64Byung H Kim, 85Helen Kim, 58
Connected to:
Nathan Aazzerah, 67Peter J Ab, 45Ahmed A Aba, 51Gina L Aba, 59Mark A Aba, 69Zayn Abaakil, 45Laura I Abaandou, 44Getamesay E Ababa, 46Edward Ababaians, 82Aaron K Ababio, 34

Naing Aay Phones & Addresses

  • 112 N Rochester St, San Mateo, CA 94401 (650) 343-5454
  • 37468 Rockwood Dr, Fremont, CA 94536
  • 112 N Rochester St, San Mateo, CA 94401

Work

Company: Exelixis Sep 2001 to Feb 2011 Position: Senior manager, combinatorial and medicinal chemistry

Education

School / High School: University of California, Berkeley Extension

Emails

j***[email protected]

Industries

Biotechnology

Resumes

Resumes

Naing Aay Photo 1

Data Analyst Sas

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Location:
San Francisco Bay Area
Industry:
Biotechnology
Work:
Exelixis Sep 2001 - Feb 2011
Senior Manager, Combinatorial and Medicinal Chemistry
PHARMCHEM Inc., Menlo Park, CA 1992 - 2001
GC/MS Analyst
Education:
University of California, Berkeley Extension
University of Rangoon, Rangoon, Burma

Publications

Us Patents

Azetidines As Mek Inhibitors For The Treatment Of Proliferative Diseases

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US Patent:
7915250, Mar 29, 2011
Filed:
May 5, 2010
Appl. No.:
12/774544
Inventors:
Naing Aay - San Mateo CA, US
Neel Kumar Anand - Burlingame CA, US
Charles M. Blazey - San Francisco CA, US
Owen Joseph Bowles - Pacifica CA, US
Joerg Bussenius - Foster City CA, US
Simona Costanzo - Los Altos CA, US
Jeffry Kimo Curtis - San Anselmo CA, US
Steven Charles DeFina - Burlingame CA, US
Larisa Dubenko - San Francisco CA, US
Anagha Abhijit Joshi - Fremont CA, US
Abigail R. Kennedy - Oakland CA, US
Angie Inyoung Kim - San Mateo CA, US
Elena S. Koltun - Foster City CA, US
Jean-Claire Limun Manalo - Daly City CA, US
Csaba J. Peto - Alameda CA, US
Kenneth D. Rice - San Rafael CA, US
Tsze H. Tsang - El Cerrito CA, US
Assignee:
Exelixis, Inc. - South San Francisco CA
International Classification:
A61K 31/397
A61K 31/50
A61K 31/505
A61K 31/4523
A61K 31/4178
US Classification:
51421018, 514248, 51425203, 51425205, 514256, 514318, 514403, 544235, 544242, 544333, 544405, 546208, 546210, 5462681, 5462684, 5462754
Abstract:
Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.

Tropane Compounds

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US Patent:
8012956, Sep 6, 2011
Filed:
Oct 27, 2008
Appl. No.:
12/290159
Inventors:
Kenneth D. Rice - San Rafael CA, US
Naing Aay - San Mateo CA, US
Neel Kumar Anand - Burlingame CA, US
Arlyn Arcalas - South San Francisco CA, US
Charles M. Blazey - San Francisco CA, US
Owen Joseph Bowles - Pacifica CA, US
Chris A. Buhr - Redwood City CA, US
Joerg Bussenius - Foster City CA, US
Simona Costanzo - Los Altos CA, US
Jeffrey Kimo Curtis - San Anselmo CA, US
Steven Charles Defina - Burlingame CA, US
Larisa Dubenko - San Francisco CA, US
Abigail R. Kennedy - Oakland CA, US
Angie Inyoung Kim - San Mateo CA, US
Katherine Lara - San Mateo CA, US
Sunghoon Ma - Foster City CA, US
Jean-Claire Limun Manalo - Daly City CA, US
Csaba J. Peto - Alameda CA, US
Tsze H. Tsang - El Cerrito CA, US
Longcheng Wang - Palo Alto CA, US
Assignee:
Exelixis, Inc. - South San Francisco CA
International Classification:
A61K 31/46
A61K 31/5377
A61K 31/496
A61K 31/497
C07D 451/04
US Classification:
51421021, 5142332, 51425304, 51425505, 514304, 546124, 546125, 544127, 544362, 544405
Abstract:
A compound according to Formula I or II:.

6-Phenylpyrimidinones As Pim Modulators

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US Patent:
8242129, Aug 14, 2012
Filed:
Apr 25, 2008
Appl. No.:
12/597275
Inventors:
Amy L. Tsuhako - Milpitas CA, US
Naing Aay - San Mateo CA, US
S. David Brown - San Carlos CA, US
Wai Ki Vicky Chan - San Francisco CA, US
Hongwang Du - Millbrae CA, US
Ping Huang - Mountain View CA, US
Brian Kane - Lynchburg VA, US
Patrick Kearney - San Francisco CA, US
Moon Hwan Kim - Palo Alto CA, US
Elena S. Koltun - Foster City CA, US
Michael Pack - San Francisco CA, US
Wei Xu - Danville CA, US
Peiwen Zhou - Palo Alto CA, US
Assignee:
Exelixis, Inc. - South San Francisco CA
International Classification:
A61K 31/505
US Classification:
514274, 544309, 544310, 544316, 544317
Abstract:
A compound having Formula I or II (Formula I) or (Formula II), or a pharmaceutically acceptable salt thereof, wherein X, Z, R, R, Rand Rare as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.

Pyrimidinones As Casein Kinase Ii (Ck2) Modulators

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US Patent:
8324231, Dec 4, 2012
Filed:
Apr 24, 2008
Appl. No.:
12/597271
Inventors:
Elena S. Koltun - Foster City CA, US
Patrick Kearney - San Francisco CA, US
Naing Aay - San Mateo CA, US
Arlyn Arcalas - South San Francisco CA, US
Wai Ki Vicky Chan - San Francisco CA, US
Jeffry Kimo Curtis - San Anselmo CA, US
Hongwang Du - Millbrae CA, US
Ping Huang - Mountain View CA, US
Brian Kane - Lynchburg VA, US
Moon Hwan Kim - Palo Alto CA, US
Michael Pack - San Francisco CA, US
Amy L. Tsuhako - Milpitas CA, US
Wei Xu - Danville CA, US
Cristiana A. Zaharia - Redwood City CA, US
Peiwen Zhou - Palo Alto CA, US
Assignee:
Exelixis, Inc. - South San Francisco CA
International Classification:
A01N 43/54
A61K 31/505
US Classification:
514272, 544315, 544316, 544318
Abstract:
A compound having Formula I: or a pharmaceutically acceptable salt thereof, wherein X, R, R and R are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof. The compounds of Formula I are inhibitors of Casein kinase II (CK2) pathways.

Azetidines As Mek Inhibitors For The Treatment Of Proliferative Diseases

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US Patent:
8362002, Jan 29, 2013
Filed:
Mar 15, 2011
Appl. No.:
13/048832
Inventors:
Naing Aay - San Mateo CA, US
Neel Kumar Anand - Burlingame CA, US
Charles M. Blazey - San Francisco CA, US
Owen Joseph Bowles - Pacifica CA, US
Joerg Bussenius - Foster City CA, US
Simona Costanzo - Los Altos CA, US
Jeffry Kimo Curtis - San Anselmo CA, US
Steven Charles DeFina - Burlingame CA, US
Larisa Dubenko - San Francisco CA, US
Anagha Abhijit Joshi - Fremont CA, US
Abigail R. Kennedy - Oakland CA, US
Angie Inyoung Kim - San Mateo CA, US
Elena S. Koltun - Foster City CA, US
Jean-Claire Limun Manalo - Daly City CA, US
Csaba J. Peto - Alameda CA, US
Kenneth D. Rice - San Rafael CA, US
Tsze H. Tsang - El Cerrito CA, US
Assignee:
Exelixis, Inc. - San Francisco CA
International Classification:
A61K 31/397
A61K 31/50
A61K 31/505
A61K 31/4523
A61K 31/4178
US Classification:
51421018, 514248, 51425203, 51425205, 514256, 514318, 514403, 544235, 544242, 544333, 544405, 546208, 546210, 5462681, 5462684, 5462754
Abstract:
Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.

4-Aryl-2-Amino-Pyrimidines Or 4-Aryl-2-Aminoalkyl-Pyrimidines As Jak-2 Modulators And Methods Of Use

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US Patent:
8440663, May 14, 2013
Filed:
Jan 30, 2007
Appl. No.:
11/992224
Inventors:
Grace Mann - San Mateo CA, US
Naing Aay - San Mateo CA, US
Arlyn Arcalas - South San Francisco CA, US
S. David Brown - San Carlos CA, US
Wai Ki Vicky Chan - San Francisco CA, US
Jeff Chen - San Francisco CA, US
Hongwang Du - Millbrae CA, US
Sergey Epshteyn - Fremont CA, US
Timothy Patrick Forsyth - Hayward CA, US
Adam A. Galan - Alameda CA, US
Tai Phat Huynh - New York City NY, US
Mohamed Abdulkader Ibrahim - Mountain View CA, US
Henry William Beecroft Johnson - San Bruno CA, US
Brian Kane - Lynchburg VA, US
Patrick Kearney - San Francisco CA, US
Byung Gyu Kim - San Mateo CA, US
Elena S. Koltun - Foster City CA, US
James W. Leahy - San Leandro CA, US
Matthew Sangyup Lee - San Bruno CA, US
Gary L. Lewis - San Francisco CA, US
Lisa E. Meyr - Seattle WA, US
Robin Tammie Noguchi - San Bruno CA, US
Michael Pack - San Francisco CA, US
Brian Hugh Ridgway - Belmont CA, US
Xian Shi - San Bruno CA, US
John Woolfrey - Los Altos CA, US
Peiwen Zhou - Palo Alto CA, US
Assignee:
Exelixis, Inc. - South San Francisco CA
International Classification:
A61K 31/535
C07D 239/24
C07D 401/10
C07D 413/10
US Classification:
5142358, 544323, 544324, 544333
Abstract:
This invention relates to certain pyrimidine derivative inhibitors of JAK-2, having Formula (I): wherein D, E, L, Z, R, R, R, and n1 are as defined in the specification, pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, and methods of use thereof.

Benzoxazepines As Inhibitors Of Pi3K/Mtor And Methods Of Their Use And Manufacture

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US Patent:
8637499, Jan 28, 2014
Filed:
May 25, 2010
Appl. No.:
13/322160
Inventors:
Naing Aay - San Mateo CA, US
Arlyn Arcalas - South San Francisco CA, US
Joerg Bussenius - Foster City CA, US
Steven Charles DeFina - Oakland CA, US
Larisa Dubenko - San Francisco CA, US
Jason R. Harris - San Bruno CA, US
Eileen E. Jackson-Ugueto - Basel, CH
Angie Inyoung Kim - San Mateo CA, US
Jean-Claire Limun Manalo - Daly City CA, US
Michael Pack - Fukuoka, JP
Csaba J. Peto - Alameda CA, US
Kenneth D. Rice - San Rafael CA, US
Tsze H. Tsang - El Cerrito CA, US
Owen Joseph Bowles - Pacifica CA, US
Jeffry Kimo Curtis - San Anselmo CA, US
Assignee:
Exelixis, Inc. - South San Francisco CA
International Classification:
A61P 35/00
A61K 31/553
C07D 267/14
US Classification:
51421109, 540552
Abstract:
The invention is directed to Compounds of Formula (I): the invention provides compounds that inhibit, regulate, and/or modulate P13K and/or mTOR that are useful in the treatment of hyperproliferative diseases, such as cancer, in mammals. This invention also provides methods of making the compound methods of using such compounds in the treatment of hyperproliferative diseases in mammals, especially humans, and to pharmaceutical compositions containing such compounds. For example, cancer in which activity against PI3fC-alph mTOR, or both contributes to its pathology and/or symptomatology include breast cancer mantle cell lymphoma, renal cell carcinoma, acute myelogenous leukemia, chronic myelogenous leukemia, NPM/ALK-transformed anaplastic large cell lymphoma, diffu large B cell lymphoma, rhabdomyosarcoma, ovarian cancer, endometrial cancer, cervic cancer, non small cell lung carcinoma, small cell lung carcinoma, adenocarcinoma, col cancer, rectal cancer, gastric carcinoma, hepatocellular carcinoma, melanoma, pancreat cancer, prostate carcinoma, thyroid carcinoma, anaplastic large cell lymphoma, hemangiom glioblastoma, or head and neck cancer.

Azetidines As Mek Inhibitors For The Treatment Of Proliferative Diseases

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US Patent:
20090156576, Jun 18, 2009
Filed:
Oct 5, 2006
Appl. No.:
11/995928
Inventors:
Naing Aay - San Mateo CA, US
Neel Kumar Anand - Burlingame CA, US
Charles M. Blazey - San Francisco CA, US
Owen Joseph Bowles - Pacifica CA, US
Joerg Bussenius - Foster City CA, US
Simona Costanzo - Los Altos CA, US
Jeffry Kimo Curtis - San Anselmo CA, US
Steven Charles DeFina - Burlingame CA, US
Larisa Dubenko - San Francisco CA, US
Anagha Abhijit Joshi - Fremont CA, US
Abigail R. Kennedy - Oakland CA, US
Angie Inyoung Kim - San Mateo CA, US
Elena S. Koltun - Foster City CA, US
Jean-Claire Limun Manalo - Daly City CA, US
Csaba J. Peto - Alameda CA, US
Kenneth D. Rice - San Rafael CA, US
Tsze H. Tsang - El Cerrito CA, US
Assignee:
EXELIXIS INC. - South San Francisco CA
International Classification:
A61K 31/397
C07D 205/04
C07D 401/14
C07D 403/06
C07D 471/04
C07D 413/06
US Classification:
51421018, 548952, 51421017, 544238, 544359, 546208, 546121, 544111
Abstract:
Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
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Naing A Aay from San Mateo, CA, age ~62 Get Report