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Nadia Dahmane

from Philadelphia, PA
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Connected to:
Mohamed A Dahmani, 67Fadi N Dahmash, 47Ann F Dahme, 91Bettylou A Dahme, 81Michael W Dahme, 45Sara B Dahme, 46Caroline Dahmen, 32Doris M Dahmen, 93Glenn E Dahmen, 52Jessica R Dahmen, 39

Nadia Dahmane Phones & Addresses

  • Philadelphia, PA

Publications

Us Patents

Steroid-Derived Cyclopamine Analogs And Methods For Using The Same In The Prevention Or Treatment Of Cancer

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US Patent:
20100298281, Nov 25, 2010
Filed:
Oct 30, 2008
Appl. No.:
12/739991
Inventors:
Nadia Dahmane - Philadelphia PA, US
Jeffrey D. Winkler - Wynnewood PA, US
Assignee:
THE WISTAR INSTITUTE - Philadelphia PA
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA
International Classification:
A61K 31/58
C07J 21/00
C12N 5/02
A61P 35/00
A61P 35/02
US Classification:
514173, 540 28, 435375
Abstract:
The present invention relates to steroid-derived cyclopamine analogs and methods for using the same for inhibiting sonic hedgehog signaling and preventing or treating cancer. A method for synthesizing the analogs of the present invention from a steroid is also provided.

Steroid-Derived Cyclopamine Analogs And Methods For Using The Same In The Prevention Or Treatment Of Cancer

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US Patent:
20110306662, Dec 15, 2011
Filed:
Jun 15, 2011
Appl. No.:
13/160702
Inventors:
Nadia Dahmane - Philadelphia PA, US
Jeffrey D. Winkler - Wynnewood PA, US
Assignee:
The Wistar Institute and The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
A61K 31/343
C12N 5/09
A61P 35/04
C07D 307/94
A61P 35/00
US Classification:
514462, 549345, 435375
Abstract:
The present invention relates to steroid-derived cyclopamine analogs and methods for using the same for inhibiting sonic hedgehog signaling and preventing or treating cancer. A method for synthesizing the analogs of the present invention from a steroid is also provided.
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