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Muthunadar P Periasamy

from Chesterfield, MO
Age ~76
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Also known as:
Muthana P Periasamy, Muthunadar P Perasamy, R Periasamy, D Periasamy, A Periasamy
Phone and address:
14640 Big Timber Ln, Wildwood, MO 63017
(636) 532-8245
Related to:
Kami WaldmanAngelo B Lipira, 43Robin M Kimberlin, 46C L Periasamy, 72Evan S Waldman, 43Michael T Kimberlin, 47
Connected to:
Ganesh Periaswamy, 45John J Periatt, 64Adrian Peric, 65Aleksandar Peric, 32Branko L Peric, 102Bratislav T Peric, 50Christine A Peric, 66Gerald G Peric, 63Marinko P Peric, 50Natasha V Peric, 51

Muthunadar Periasamy Phones & Addresses

  • 14640 Big Timber Ln, Chesterfield, MO 63017 (636) 532-8245
  • Saint Louis, MO
  • Hazelwood, MO

Work

Address: 14640 Big Timber Lane, Chesterfield, MO 63017

Ranks

Licence: Missouri - Good Standing, Active Date: 2008

Professional Records

Lawyers & Attorneys

Muthunadar Periasamy Photo 1

Muthunadar Peri Periasamy, Chesterfield MO - Lawyer

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Address:
14640 Big Timber Lane, Chesterfield, MO 63017
Licenses:
Missouri - Good Standing, Active 2008

Publications

Us Patents

Light Sensitive Compounds For Instant Determination Of Organ Function

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US Patent:
7175831, Feb 13, 2007
Filed:
Jan 2, 2004
Appl. No.:
10/751232
Inventors:
Samuel Achilefu - St. Louis MO, US
Raghavan Rajagopalan - Solon OH, US
Richard B. Dorshow - St. Louis MO, US
Joseph E. Bugaj - St. Charles MO, US
Hermo N. Jimenez - Hazelwood MO, US
Muthunadar P. Periasamy - Chesterfield MO, US
Assignee:
Mallinckrodt, Inc. - St. Louis MO
International Classification:
A61B 10/00
A61B 5/00
A61B 8/00
US Classification:
424 96, 424 111, 424 165, 424 91, 514373
Abstract:
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.

Tumor-Targeted Optical Contrast Agents

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US Patent:
7198778, Apr 3, 2007
Filed:
Sep 3, 2003
Appl. No.:
10/654033
Inventors:
Samuel I. Achilefu - St. Louis MO, US
Raghavan Rajagopalan - Solon OH, US
Richard B. Dorshow - St. Louis MO, US
Joseph E. Bugaj - St. Charles MO, US
Muthunadar P. Periasamy - Chesterfield MO, US
Assignee:
Mallinckrodt Inc. - St. Louis MO
International Classification:
A61B 10/00
A61B 8/00
US Classification:
424 96, 424 111, 424 165, 424 91, 424 93, 424 94, 424 95, 548146
Abstract:
Cyanine dye bioconjugates useful for diagnostic imaging and therapy are disclosed. The conjugates include several cyanine dyes with a variety of bis- and tetrakis (carboxylic acid) homologs. The compounds may be conjugated to bioactive peptides, carbohydrates, hormones, drugs, or other bioactive agents. The small size of the compounds allows more favorable delivery to tumor cells as compared to larger molecular weight imaging agents. The various dyes are useful over the range of 350 to 1300 nm, the exact range being dependent upon the particular dye. The use of dimethylsulfoxide helps to maintain the fluorescence of the compounds. The inventive compounds are useful for diagnostic imaging and therapy, in endoscopic applications for the detection of tumors and other abnormalities, for localized therapy, for photoacoustic tumor imaging, detection and therapy, and for sonofluoresence tumor imaging, detection and therapy.

Compounds For Dual Photodiagnosis And Therapy

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US Patent:
7230088, Jun 12, 2007
Filed:
Oct 14, 2003
Appl. No.:
10/685172
Inventors:
Raghavan Rajagopalan - Solon OH, US
Samuel I. Achilefu - St. Louis MO, US
Joseph E. Bugaj - St. Charles MO, US
Richard B. Dorshow - St. Louis MO, US
Muthunadar P. Periasamy - Chesterfield MO, US
Assignee:
Mallinckrodt, Inc. - St. Louis MO
International Classification:
C07K 1/13
G01N 33/531
G01N 33/533
US Classification:
530405, 530403, 436546, 436 56, 436800
Abstract:
The invention discloses compounds and compositions for dual phototherapy and combined therapy and diagnosis of tumors and other lesions. The compounds have a Dye that, when photoactivated, operates via Type I and/or Type II mechanisms. Other Dye or azide components may operate by the same or different mechanisms. Selection of particular components in a compound, and formulation of the compound(s) in a composition permit different activation wavelengths to be used for different therapies. A targeting moiety may be added to the compound or composition so that the Dye locates at a particular site, such as a hormone-sensitive tumor, for diagnosis and/or treatment. The compounds and compositions may be incorporated within liposomes.

Hydrophilic Light Absorbing Compositions For Determination Of Physiological Function

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US Patent:
7297325, Nov 20, 2007
Filed:
Dec 23, 2003
Appl. No.:
10/744334
Inventors:
Samuel Achilefu - St. Louis MO, US
Raghavan Rajagopalan - Solon OH, US
Richard B. Dorshow - St. Louis MO, US
Joseph E. Bugaj - St. Charles MO, US
Muthunadar P. Periasamy - Chesterfield MO, US
Assignee:
Mallinckrodt Inc. - St. Louis MO
International Classification:
A61K 51/00
A61M 36/14
US Classification:
424 189, 424 111, 424 165, 424 181, 424 185, 424 91, 424 95, 424 951, 424 952, 424 96, 424450, 424489
Abstract:
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.

Dyes For Organ Function Monitoring

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US Patent:
7438894, Oct 21, 2008
Filed:
Oct 7, 2003
Appl. No.:
10/680338
Inventors:
Samuel Achilefu - St. Louis MO, US
Raghavan Rajagopalan - Solon OH, US
Richard B. Dorshow - St. Louis MO, US
Joseph E. Bugaj - St. Charles MO, US
Muthunadar P. Periasamy - Chesterfield MO, US
Assignee:
Mallinckrodt, Inc. - St. Louis MO
International Classification:
A61B 10/00
A61B 5/00
A61B 8/00
US Classification:
424 96, 424 111, 424 165, 424 91, 424 93, 424 94, 424 95, 548146
Abstract:
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.

Hydrophilic Light Absorbing Compositions For Determination Of Physiological Function In Critically Ill Patients

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US Patent:
7468177, Dec 23, 2008
Filed:
Jul 16, 2007
Appl. No.:
11/778424
Inventors:
Samuel Achilefu - St. Louis MO, US
Raghavan Rajagopalan - Solon OH, US
Richard B. Dorshow - St. Louis MO, US
Joseph E. Bugaj - St. Charles MO, US
Muthunadar P. Periasamy - Chesterfield MO, US
Assignee:
Mallinckrodt Inc. - Hazelwood MO
International Classification:
A61K 49/00
US Classification:
424 91, 424 111, 424 165, 424 93, 424 94, 424 95, 424 96, 424 97, 424 98, 548400
Abstract:
Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.

Receptor-Avid Exogenous Optical Contrast And Therapeutic Agents

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US Patent:
7504087, Mar 17, 2009
Filed:
Mar 9, 2005
Appl. No.:
11/075792
Inventors:
Samuel I. Achilefu - St. Louis MO, US
Raghavan Rajagopalan - Solon OH, US
Richard B. Dorshow - St. Louis MO, US
Joseph E. Bugaj - Richmond CA, US
Muthunadar P. Periasamy - Chesterfield MO, US
Assignee:
Mallinkrodt Inc. - Hazelwood MO
International Classification:
A61K 51/00
A61M 36/14
US Classification:
424 169, 424 111, 424 165
Abstract:
Cyanine and Indocyanine dye compounds and bioconjugates are disclosed. The present invention includes several cyanine and indocyanine dyes, including bioconjugates of the same, with a variety of bis- and tetrakis (carboxylic acid) homologues. The compounds of the invention may be conjugated to bioactive peptides, carbohydrates, hormones, drugs, or other bioactive agents. The small size of compounds of the invention allows favorable delivery to tumor cells as compared to larger molecular weight imaging agents. Further, use of a biocompatible organic solvent such as dimethylsulfoxide may be said to assist in maintaining the fluorescence of compounds of the invention. The compounds and bioconjugates herein disclosed are useful in a variety of medical applications including, but not limited to, diagnostic imaging and therapy, endoscopic applications for the detection of tumors and other abnormalities, localized therapy, photoacoustic tumor imaging, detection and therapy, and sonofluorescence tumor imaging, detection and therapy.

Tumor-Targeted Optical Contrast Agents

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US Patent:
7514069, Apr 7, 2009
Filed:
Mar 5, 2007
Appl. No.:
11/682032
Inventors:
Samuel I. Achilefu - St. Louis MO, US
Raghavan Rajagopalan - Solon OH, US
Richard B. Dorshow - St. Louis MO, US
Joseph E. Bugaj - St. Charles MO, US
Muthunadar P. Periasamy - Chesterfield MO, US
Assignee:
Mallinckrodt Inc. - Hazelwood MO
International Classification:
A61B 10/00
A61B 5/00
A61B 8/00
US Classification:
424 96, 424 111, 424 149, 424 165, 424 169, 424 173, 424 91, 5483001
Abstract:
Cyanine dye bioconjugates useful for diagnostic imaging and therapy are disclosed. The conjugates include several cyanine dyes with a variety of bis- and tetrakis (carboxylic acid) homologs. The compounds may be conjugated to bioactive peptides, carbohydrates, hormones, drugs, or other bioactive agents. The small size of the compounds allows more favorable delivery to tumor cells as compared to larger molecular weight imaging agents. The various dyes are useful over the range of 350 to 1300 nm, the exact range being dependent upon the particular dye. The use of dimethylsulfoxide helps to maintain the fluorescence of the compounds. The inventive compounds are useful for diagnostic imaging and therapy, in endoscopic applications for the detection of tumors and other abnormalities, for localized therapy, for photoacoustic tumor imaging, detection and therapy, and for sonofluoresence tumor imaging, detection and therapy.
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Muthunadar P Periasamy from Chesterfield, MO, age ~76 Get Report