Resumes
Resumes
Mustafa Yazicioglu Phones & Addresses
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Broomall, PA
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Reno, NV
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74 Drexelbrook Dr, Drexel Hill, PA 19026
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14555 Philippine St, Houston, TX 77040
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5454 Amesbury Dr, Dallas, TX 75206
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11815 Jamestown Rd, Dallas, TX 75230
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10001 Preston Rd, Dallas, TX 75230
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Philadelphia, PA
Publications
Us Patents
Prrg4-Associated Compositions And Methods Of Use Thereof In Methods Of Tumor Diagnosis
View pageUS Patent:
20100017897, Jan 21, 2010
Filed:
Jun 8, 2009
Appl. No.:
12/480426
Inventors:
Katherine A. High - Merion PA, US
Fayaz R. Khazi - Swedesboro NJ, US
Kirk Chu - Narberth PA, US
Luca Monaldini - Turate, IT
Mustafa Naci Yazicioglu - Drexel Hill PA, US
Samuel Murphy - Philadelphia PA, US
Fayaz R. Khazi - Swedesboro NJ, US
Kirk Chu - Narberth PA, US
Luca Monaldini - Turate, IT
Mustafa Naci Yazicioglu - Drexel Hill PA, US
Samuel Murphy - Philadelphia PA, US
International Classification:
A01K 67/027
C12Q 1/68
C12Q 1/02
G01N 33/53
C40B 30/04
G01N 33/68
A61K 31/7088
C12Q 1/68
C12Q 1/02
G01N 33/53
C40B 30/04
G01N 33/68
A61K 31/7088
US Classification:
800 3, 435 6, 435 29, 435 71, 435 792, 506 9, 436 86, 800 13, 514 44 A
Abstract:
Compositions and methods for detecting PRRG4- and PRRG2 associated molecules are provided as are methods of use thereof for the detection and treatment of cancer.
Secretable Protein Induced Immune Tolerization And Treatment Of Autoimmune, Allergic And Other Diseases And Disorders
View pageUS Patent:
20230040275, Feb 9, 2023
Filed:
Nov 19, 2020
Appl. No.:
17/777954
Inventors:
- Philadelphia PA, US
Brittney L. GURDA - Collegeville PA, US
Federico MINGOZZI - Philadelphia PA, US
Mustafa N. YAZICIOGLU - Broomall PA, US
William QUINN - Philadelphia PA, US
Brittney L. GURDA - Collegeville PA, US
Federico MINGOZZI - Philadelphia PA, US
Mustafa N. YAZICIOGLU - Broomall PA, US
William QUINN - Philadelphia PA, US
Assignee:
SPARK THERAPEUTICS, INC. - Philadelphia PA
International Classification:
C12N 15/62
A61K 39/35
A61K 39/00
C07K 14/705
C12N 15/86
A61K 48/00
A61P 37/06
A61K 31/436
C07K 14/47
C07K 14/005
A61K 39/35
A61K 39/00
C07K 14/705
C12N 15/86
A61K 48/00
A61P 37/06
A61K 31/436
C07K 14/47
C07K 14/005
Abstract:
Nucleic acids encoding fusion proteins that contain an unwanted antigen and a leader sequence for cell secretion are described. Also described are expression cassettes, vectors, cells, and cell lines containing the nucleic acids, as well as methods of using the nucleic acids to treat autoimmune, allergic and other diseases and disorders, such as multiple sclerosis.
Engineered Aav Capsids With Increased Tropism And Aav Vectors Comprising The Engineered Capsids And Methods Of Making And Using Same
View pageUS Patent:
20210363192, Nov 25, 2021
Filed:
Apr 26, 2019
Appl. No.:
17/050362
Inventors:
- Philadelphia PA, US
Sean ARMOUR - Holland PA, US
Nicholas KEISER - Bryn Mawr PA, US
Suryanarayan SOMANATHAN - Shrewsbury MA, US
Mustafa N. YAZICIOGLU - Broomall PA, US
Sean ARMOUR - Holland PA, US
Nicholas KEISER - Bryn Mawr PA, US
Suryanarayan SOMANATHAN - Shrewsbury MA, US
Mustafa N. YAZICIOGLU - Broomall PA, US
Assignee:
SPARK THERAPEUTICS, INC. - Philadelphia PA
International Classification:
C07K 14/005
C12N 7/00
C12N 15/86
C12N 15/113
C12N 7/00
C12N 15/86
C12N 15/113
Abstract:
The invention provides modified adeno-associated virus (AAV) capsid proteins. Modified AAV capsid proteins include, for example, capsid proteins modified to have a peptide insertion comprising a nuclear localization signal (NLS) sequence, capsid proteins modified to have an amino acid substitution at an RXXL site or a (L/P)PXY site, where X can be any amino acid, and capsid proteins modified to have one or more particular amino acid positions substituted with a different amino acid.
Variant Aav And Compositions, Methods And Uses For Gene Transfer To Cells, Organs And Tissues
View pageUS Patent:
20150023924, Jan 22, 2015
Filed:
Jul 22, 2014
Appl. No.:
14/338200
Inventors:
- Philadelphia PA, US
Mustafa Yazicioglu - Philadelphia PA, US
Xavier Anguela - Philadelphia PA, US
Mustafa Yazicioglu - Philadelphia PA, US
Xavier Anguela - Philadelphia PA, US
International Classification:
C12N 15/86
A61K 48/00
A61K 38/48
C07K 14/005
A61K 48/00
A61K 38/48
C07K 14/005
US Classification:
424 932, 4353201, 530350, 435456
Abstract:
The invention relates to adeno-associated virus (AAV) serotype AAV-Rh74 and related AAV vectors, and AAV-Rh74 and related AAV vector mediated gene transfer methods and uses. In particular, AAV-Rh74 and related AAV vectors target polynucleotides to cells, tissues or organs for expression (transcription) of genes encoding therapeutic proteins and peptides, and polynucleotides that function as or are transcribed into inhibitory nucleic acid sequences.