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Monica Vicarel Phones & Addresses

  • Strongsville, OH
  • 1042 Susan Rd, Ravenna, OH 44266 (330) 509-0603
  • Youngstown, OH
  • South Plainfield, NJ
  • Basking Ridge, NJ
  • North Jackson, OH
  • North Brunswick, NJ
  • Struthers, OH
  • Mesa, AZ
  • 2266 Country Ln, Youngstown, OH 44514 (330) 619-0095

Work

Company: Gebauer company Dec 2017 to Jan 2019 Position: Research and development scientist ii

Education

Degree: Master of Science, Masters School / High School: Youngstown State University Specialities: Chemistry

Skills

Organic Synthesis • Medicinal Chemistry • Formulation Chemistry • Analytical Chemistry • Aerosol Chemistry/Technology • Adme • Chromatography • Research and Development • Drug Discovery • Gmp

Industries

Medical Devices

Resumes

Resumes

Monica Vicarel Photo 1

Monica Vicarel

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Location:
Cleveland, OH
Industry:
Medical Devices
Work:
Gebauer Company Dec 2017 - Jan 2019
Research and Development Scientist Ii

Boehringer Ingelheim/Ben Venue 2011 - 2012
Chemist

Merck 2006 - 2011
Research Scientist
Education:
Youngstown State University
Master of Science, Masters, Chemistry
Skills:
Organic Synthesis
Medicinal Chemistry
Formulation Chemistry
Analytical Chemistry
Aerosol Chemistry/Technology
Adme
Chromatography
Research and Development
Drug Discovery
Gmp

Publications

Us Patents

Gamma Secretase Modulators

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US Patent:
20110294756, Dec 1, 2011
Filed:
Nov 12, 2009
Appl. No.:
13/128493
Inventors:
Zhaoning Zhu - Plainsboro NJ, US
William J. - Greenlee NJ, US
Xianhai Huang - Warren NJ, US
Jun Qin - Somerset NJ, US
XIaoxiang Liu - River Vale NJ, US
Hongmei Li - Warren NJ, US
Wei Zhou - Kenliworth NJ, US
Anandan Palani - Bridgewater NJ, US
Xiaohong Zhu - Edison NJ, US
Monica L. Vicarel - Basking Ridge NJ, US
Mihirbaran Mandal - Scotch Plains NJ, US
Chad E. Bennett - Metuchen NJ, US
Troy Michael McCracken - Garwood NJ, US
Gioconda V. Gallo - Summit NJ, US
International Classification:
A61K 31/695
C07D 413/10
C07D 471/04
A61P 25/28
A61K 31/519
C07D 498/20
C07F 7/18
C07D 498/04
A61K 31/5395
US Classification:
514 63, 544 66, 544282, 5142292, 51425941
Abstract:
In its many embodiments, the present invention provides a novel class of heterocyclic compounds of Group A or Group, as defined herein, as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.

Gamma Secretase Modulators

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US Patent:
20110306593, Dec 15, 2011
Filed:
Nov 11, 2009
Appl. No.:
13/128316
Inventors:
Zhaoning Zhu - Plainsboro NJ, US
William J. Greenlee - Teaneck NJ, US
Hongmei Li - Warren NJ, US
Monica L. Vicarel - North Brunswick NJ, US
Jun Qin - Edison NJ, US
Pawan Kumar Dhondi - Elizabeth NJ, US
Xianhai Huang - Warren NJ, US
Anandan Palani - Bridgewater NJ, US
Xiaoxiang Liu - River Vale NJ, US
Hubert B. Josien - Jersey City NJ, US
Ruo Xu - Watchung NJ, US
David James Cole - Springfield NJ, US
Duane A. Burnett - Bernardsville NJ, US
Chad E. Bennett - Metuchen NJ, US
Troy McCracken - Garwood NJ, US
Malcolm MacCoss - Seabrook Island SC, US
International Classification:
A61K 31/553
C07D 498/10
C07D 498/04
A61P 25/28
C07D 413/14
C07D 498/14
A61K 31/5395
C07D 498/20
C07D 413/10
US Classification:
51421108, 544 66, 540545, 5142292
Abstract:
In its many embodiments, the present invention provides a novel class of heterocyclic compounds of the formula: as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more disease associated with the central nervous system using such compounds or pharmaceutical compostions.

Fused Bicyclic Heterocycles Useful As Dipeptidyl Peptidase-Iv Inhibitors

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US Patent:
20130324562, Dec 5, 2013
Filed:
Mar 1, 2012
Appl. No.:
14/000641
Inventors:
Chad E. Bennett - Metuchen NJ, US
Duane A. Burnett - Bernardsville NJ, US
Hongmei Li - Warren NJ, US
Yonggang Chen - Westfield NJ, US
Troy McCracken - Garwood NJ, US
Monica Vicarel - Ravenna OH, US
International Classification:
C07D 487/04
A61K 45/06
A61K 31/522
A61K 31/519
C07D 473/28
US Classification:
51426322, 544280, 5142651, 544276
Abstract:
The present invention is directed to novel bicyclic heterocycles of structural formula (I) which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

Gamma Secretase Modulators

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US Patent:
20110257156, Oct 20, 2011
Filed:
Nov 5, 2009
Appl. No.:
13/126056
Inventors:
Zhaoning Zhu - Plainsboro NJ, US
William J. Greenlee - Teaneck NJ, US
David James Cole - Springfield NJ, US
Dmitri A. Pissarnitski - Scotch Plains NJ, US
Gioconda V. Gallo - Summit NJ, US
Hongmei Li - Warren NJ, US
Hubert B. Josien - Jersey City NJ, US
Jun Qin - Edison NJ, US
Chad E. Knutson - Garwood NJ, US
Mihirbaran Mandal - Scotch Plains NJ, US
Monica L. Vicarel - North Brunswick NJ, US
Murali Rajagopalan - Edison NJ, US
Pawan Kumar Dhondi - Elizabeth NJ, US
Ruo Xu - Watchung NJ, US
Thomas A. Bara - Linden NJ, US
Xianhai Huang - Warren NJ, US
Xiaohong Zhu - Edison NJ, US
Zhiqiang Zhao - Scotch Plains NJ, US
John W. Clader - Milton VT, US
Anandan Palani - Bridgewater NJ, US
Theodros Asberom - West Orange NJ, US
Troy McCracken - Garwood NJ, US
Chad E. Bennett - Metuchen NJ, US
International Classification:
A61K 31/55
A61K 31/5383
A61K 31/5377
A61K 31/501
A61K 31/497
A61K 31/506
A61K 31/438
A61K 31/437
C07D 413/10
C07D 498/20
C07D 498/04
A61P 25/00
A61P 25/28
A61K 31/4245
A61K 31/5386
US Classification:
51421021, 51421402, 5142295, 5142302, 5142305, 5142332, 51425204, 51425304, 51425505, 514256, 514278, 514302, 514364, 540578, 544 70, 544101, 544105, 544127, 544238, 544333, 544362, 544405, 546 15, 546115, 548131
Abstract:
In its many embodiments, the present invention provides novel heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.

Devices For Dispensing A Hydrofluoroolefin Vapocoolant Composition As An Aerosol

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US Patent:
20200039732, Feb 6, 2020
Filed:
Oct 20, 2017
Appl. No.:
16/342712
Inventors:
- CLEVELAND OH, US
MONICA VICAREL - RAVENNA OH, US
RYAN SCAVINSKI - WADSWORTH OH, US
MARC KRUZER - LYNDHURST OH, US
JAMES HLEBOVY - CHAGRIN FALLS OH, US
International Classification:
B65D 83/14
B65D 83/20
B65D 83/34
B65D 83/44
Abstract:
A device for dispensing a hydrofluoroolefin vapocoolant composition as an aerosol is disclosed. The device comprises an aerosol-dispensing container comprising an internal chamber, a valve, a dispensing hole, and an actuator. The device also comprises a hydrofluoroolefin vapocoolant composition comprising HCFO-1233zd at 70% to 100% (weight/weight) and, optionally, HFO-1234ze in at 0% to 30% (weight/weight). The hydrofluoroolefin vapocoolant composition is stored within the internal chamber. The aerosol-dispensing container is configured so that depressing the actuator reversibly opens the valve to allow the hydrofluoroolefin vapocoolant composition to flow from the internal chamber, past the valve, and through the dispensing hole, thereby dispensing the hydrofluoroolefin vapocoolant composition from the aerosol-dispensing container. A method of treating pain and/or swelling of a tissue of a patient by use of the device also is disclosed. The method comprises a step of dispensing the hydrofluoroolefin vapocoolant composition from the device onto the tissue of the patient.
Monica L Vicarel from Strongsville, OH, age ~45 Get Report