Inventors:
Tetsu Kawano - Kobe, JP
Seiichi Kobayashi - Belmont MA, US
Minghuang Zhang - Windham NH, US
Hiroshi Shirota - Belmont MA, US
Assignee:
Eisai R&D Management Co., Ltd. - Tokyo
International Classification:
A61K 31/7016
A61P 29/00
A61P 31/00
Abstract:
The invention provides methods of reducing the severity of mucositis, involving administration of a toll-like receptor 4 antagonist.