Min Yu Hu

8420811, Apr 16, 2013

Jun 4, 2009

12/995776

Paul Lobben - Lawrenceville NJ, US
Rulin Zhao - Pennington NJ, US
Bei Wang - Yardley PA, US
Shuang Liu - Schenectady NY, US
Min Hu - Schenectady NY, US
Yuh-Lin Allen Yang - Slingerlands NY, US
Matthew Isherwood - Delmar NY, US
Rasidul Amin - East Greenbush NY, US
Wenge Cui - Clifton Park NY, US

Bristol-Myers Squibb Company - Princeton NJ
Albany Molecular Research, Inc. - Albany NY

C07D 401/04
A61P 25/24

544238

Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. Also disclosed are pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression and other conditions and methods for obtaining the crystalline form. One such intermediate has the following structure:.

20230003656, Jan 5, 2023

Jul 19, 2022

17/868604

- Brooklyn NY, US
Min Hu - Brooklyn NY, US

DrinkSavvy, Inc. - Brooklyn NY

G01N 21/78
G01N 31/22
G01N 33/14
B82Y 20/00

A colorimetric sensor for detecting an analyte of interest in a fluid sample includes a lamellar photonic material having alternating layers of a first polymer layer and a second polymer layer. Each first polymer layer can be a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. The photonic material is configured such that, when an analyte contacts the photonic material and becomes disposed within a cavity of the molecularly imprinted polymer, a refractive property of the photonic material changes, causing a detectable color change in the sensor.

20200114349, Apr 16, 2020

Dec 12, 2019

16/711843

- Brooklyn NY, US
Min Hu - Brooklyn NY, US

B01L 3/00
G01N 21/78
G01N 21/65
G01N 21/41
G01N 33/14

A colorimetric sensor for detecting an analyte of interest that includes multiple surfaces and a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. Each surface defines a void (e.g., a pore or a nanohole) and at least one surface defines a fluid inlet. The sensor is configured such that, when an analyte contacts the molecularly imprinted polymer and becomes disposed within the cavity, a wettability of at least one of the surfaces changes thereby to cause a detectable color change in the sensor. Optionally, the sensor may also include a metal layer at a bottom of each void or nanohole and outside a top of each void or nanohole for use as a plasmon resonance-type sensor.

20190317011, Oct 17, 2019

May 30, 2019

16/427039

- Brooklyn NY, US
Min Hu - Brooklyn NY, US

G01N 21/25
G01N 21/77
G01N 21/552
B01J 20/26
B01J 20/30
B01J 20/32

A colorimetric sensor for detecting an analyte of interest that includes a metal layer disposed upon a substrate, a plurality of nanostructures, and a corresponding plurality of metal deposits spaced apart from the metal layer. The metal layer defines a plurality of holes, each nanostructure includes a first portion disposed within a respective hole, and each metal deposit is disposed upon a second portion of a respective nanostructure. The sensor also includes a molecularly imprinted polymer layer that may cover the metal layer, the nanostructures, and/or the metal deposits. The molecularly imprinted polymer layer defines a cavity shaped to receive the analyte of interest, and the sensor is configured such that, when an analyte contacts the molecularly imprinted polymer layer and becomes disposed within the cavity, an optical property of at least a portion of the sensor changes thereby to cause a detectable color change in and/or from the sensor.

20190265169, Aug 29, 2019

Apr 11, 2019

16/381436

- Brooklyn NY, US
Min Hu - Brooklyn NY, US

G01N 21/78
G01N 21/45
G01N 21/77
G01N 31/22
G01N 33/14

A colorimetric sensor for detecting an analyte of interest in a fluid sample includes a lamellar photonic material having alternating layers of a first polymer layer and a second polymer layer. Each first polymer layer can be a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. The photonic material is configured such that, when an analyte contacts the photonic material and becomes disposed within a cavity of the molecularly imprinted polymer, a refractive property of the photonic material changes, causing a detectable color change in the sensor.

20150191494, Jul 9, 2015

Mar 18, 2015

14/661063

- Princeton NJ, US
- Albany NY, US
Bei Wang - Yardley PA, US
Shuang Liu - Schenectady NY, US
Min Hu - Schenectady NY, US
Yuh-Lin Allen Yang - Bay Point CA, US
Matthew Isherwood - Delmar NY, US
Rasidul Amin - East Greenbush NY, US
Wenge Cui - Clifton Park NY, US

C07F 5/04
C07C 217/58
C07C 215/20
C07D 413/10
C07F 5/02
C07D 237/20
C07D 401/04
C07C 223/02
C07D 217/04

Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. Also disclosed are pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression and other conditions and methods for obtaining the crystalline form.