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Milan Soukup

from Sarasota, FL
Age ~76
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Related to:
Lenka Soukup, 50
Connected to:
Aaron D Soukup, 37Alex M Soukup, 31Austin M Soukup, 30Bill G Soukup, 94Christine Soukup, 57Christian A Soukup, 53Darin J Soukup, 43Dennis M Soukup, 73Derek D Soukup, 51Donald Soukup, 73

Milan Soukup Phones & Addresses

  • 4232 Balmoral Way, Sarasota, FL 34238
  • North Lima, OH

Resumes

Resumes

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Milan Soukup

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Milan Soukup

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Location:
Sarasota, FL
Industry:
Pharmaceuticals

Business Records

Name / Title
Company / Classification
Phones & Addresses
Milan P. Soukup
Manager
Carbo-Design LLC
Business Services
4232 Balmoral Way, Sarasota, FL 34238

Publications

Us Patents

Manufacturing Process For Enantiomerically Pure 8-Aryloctanoic Acids As Aliskiren

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US Patent:
8203005, Jun 19, 2012
Filed:
Oct 15, 2010
Appl. No.:
12/925153
Inventors:
Milan Soukup - Sarasota FL, US
Assignee:
Carbo Design LLC - Sarasota FL
International Classification:
C07C 231/02
C07D 405/04
C07D 307/33
US Classification:
548517, 549321, 564157
Abstract:
The invention describes a novel technical process and novel intermediates useful for the manufacture of enantiomerically pure 8-aryloctanoic acids of the formula I which are pharmaceutically active compounds as rennin inhibitors.

Manufacturing Process For (S)-Pregabalin

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US Patent:
8466297, Jun 18, 2013
Filed:
Nov 1, 2010
Appl. No.:
12/925782
Inventors:
Milan Soukup - Sarasota FL, US
International Classification:
C07D 207/26
US Classification:
548551, 548552
Abstract:
The present invention relates to a novel manufacturing process and novel intermediates useful in the synthesis of pharmaceutically active compounds of general formula I used for treatment of epilepsy, neuropathic pain, anxiety and social phobia. The invention describes preparation of enantiomerically pure (S)-Pregabalin from chiral pyrrolidin-2-one of formula IV.

Manufacturing Process For Sitagliptin From L-Aspartic Acid

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US Patent:
8524936, Sep 3, 2013
Filed:
May 18, 2011
Appl. No.:
13/068713
Inventors:
Milan Soukup - Sarasota FL, US
International Classification:
C07C 269/00
C07C 227/10
US Classification:
560 30, 544 1, 544224, 544336, 548100, 562449
Abstract:
The present invention relates to a novel manufacturing process of pharmaceutically active compound of formula I used as oral anti-diabetic drug. Starting from L-aspartic acid derivate of formula IV the invention describes preparation of the chiral (R)-β-amino acid of formula II known as a precursor in the synthesis of Sitagliptin (formula I).

Process For The Manufacture Of Enantiomerically Pure Antifungal Azoles As Ravuconazole And Isavuconazole

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US Patent:
8207352, Jun 26, 2012
Filed:
Oct 8, 2009
Appl. No.:
12/587488
Inventors:
Milan Soukup - Sarasota FL, US
Assignee:
Drug Process Licensing Associates LLC - Dallas TX
International Classification:
C07D 249/08
US Classification:
5482666
Abstract:
A new technical process for preparation of enantiomerically pure antifungal compounds of formula I by resolution of the racemates has been disclosed.

Process For The Manufacture Of Enantiomerically Pure Aryloctanoic Acids As Aliskiren

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US Patent:
20110092706, Apr 21, 2011
Filed:
Oct 15, 2010
Appl. No.:
12/925154
Inventors:
Milan Soukup - Sarasota FL, US
Assignee:
CarboDesign LLC - Sarasota FL
International Classification:
C07C 231/12
C07D 491/052
C07D 211/42
US Classification:
546116, 546220, 546219, 564157
Abstract:
The present invention relates to a novel manufacturing process and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially rennin inhibitors such as Aliskiren. The invention describes a preparation of enantiomerically pure 8-aryloctanoic acids of general formula I from readily available key intermediate, a novel bicyclic compound of formula IV.

Process For Enantiomerically Pure 8-Aryloctanoic Acids As Aliskiren

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US Patent:
20110137047, Jun 9, 2011
Filed:
Oct 15, 2010
Appl. No.:
12/925151
Inventors:
Milan Soukup - Sarasota FL, US
Assignee:
CarboDesign LLC - Sarasota FL
International Classification:
C07C 231/02
C07D 405/04
C07D 203/08
C07D 307/33
C07C 57/13
C07C 237/22
C07C 231/12
C07C 11/28
US Classification:
548517, 548968, 549321, 562595, 564134, 564158, 585 16
Abstract:
The present invention relates to a novel manufacturing process and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially rennin inhibitors such as Aliskiren. The invention describes a preparation of enantiomerically pure 8-aryloctanoic acids of general formula I from readily available key intermediate, chiral cis-diacid of formula II, aziridine of formula XI and a monocyclic compound of formula III.

Manufacturing Process For Tadalafil From Racemic Or L-Tryptophan

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US Patent:
20120123124, May 17, 2012
Filed:
Apr 22, 2011
Appl. No.:
13/066684
Inventors:
Milan Soukup - Sarasota FL, US
Assignee:
Drug Process Licensing Associates, LLC - Dallas TX
International Classification:
C07D 471/04
US Classification:
546 85
Abstract:
The present invention relates to a novel manufacturing process of pharmaceutically active compound of formula I, having (6R,12aR)-configuration, used for treatment of erectile dysfunction. Starting from racemic or L-tryptophan the invention describes preparation of an enantiomerically pure intermediate of formula II which is a known precursor in the synthesis of Tadalafil (formula I).

Manufacturing Process For Tiotropium Bromide

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US Patent:
20120123125, May 17, 2012
Filed:
Oct 6, 2011
Appl. No.:
13/200975
Inventors:
Milan SOUKUP - Sarasota FL, US
Assignee:
Drug Process Licensing Associates, LLC - Dallas TX
International Classification:
C07D 491/08
C07D 409/14
US Classification:
546 91, 549 60
Abstract:
The present invention relates to a novel manufacturing process of pharmaceutically active compound of formula I used as a long-acting anticholinergic bronchodilator. Starting from oxalic acid derivative of formula III the invention describes preparation of a novel cyclic anhydride of formula II which is very efficient precursor in the synthesis of Tiotropium bromide (compound of formula I).
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Milan Soukup from Sarasota, FL, age ~76 Get Report