US Patent:
20120302516, Nov 29, 2012
Inventors:
Michael H. Nantz - Louisville KY, US
Souvik Biswas - Louisville KY, US
Assignee:
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. - Louisville KY
International Classification:
C07H 15/252
C07H 23/00
C07H 1/00
C07C 239/16
C07C 249/08
A61K 31/295
G01N 33/53
C07C 45/79
A61N 2/10
C07C 251/58
A61K 31/704
B82Y 40/00
B82Y 5/00
US Classification:
514 34, 536 64, 556 37, 536 55, 556138, 514502, 436501, 435 71, 568303, 568420, 600 12, 977773, 977906, 977896
Abstract:
The invention provides magnetic nanoparticles comprising a core, wherein the nanoparticles comprise at least one therapeutic agent linked to the core via a hydrazone linkage or via an oxime ether linkage, methods for making said nanoparticles, and methods for using said nanoparticles.