Inventors:
Adrian Vilalta - San Diego CA, US
Michal Margalith - Solana Beach CA, US
Lichun Dong - Seattle WA, US
David M. Koelle - Seattle WA, US
Assignee:
Vical Incorporated - San Diego CA
University of Washington - Seattle WA
International Classification:
A61K 39/245
Abstract:
This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from herpes simplex virus. Also disclosed are therapeutic compositions useful in such a method.