Melissa Hasenbank Phones & Addresses

  • 3467 W 1St St, Ludington, MI 49431
  • Free Soil, MI



Melissa Hasenbank Photo 1

Melissa Hasenbank

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Us Patents

Signal Amplification Method For Surface Plasmon Resonance-Based Chemical Detection

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US Patent:
7405054, Jul 29, 2008
Dec 13, 2005
Appl. No.:
Melissa Hasenbank - Free Soil MI, US
Paul Yager - Seattle WA, US
Elain Fu - Seattle WA, US
Kjell Nelson - Seattle WA, US
University of Washington UW Tech Transfer - Invention Licensing - Seattle WA
International Classification:
G01N 33/53
G01N 33/553
US Classification:
435 79, 422 8211, 435 6, 435 792, 4352872, 4352887, 435808, 436164, 436512, 436514, 436524, 436525, 436805, 436827
The present invention provides methods and compositions for amplifying the detection signal in surface plasmon resonance (SPR)-based flow systems. The signal amplification methods comprise the use of well established marker systems that provide a precipitate. The marker systems include, for example, enzyme and nucleation systems. Enzymes suitable for use as a marker system include peroxidases and phosphatases. The amplification system is useful in any SPR-based detection system including microfluidic systems, e. g. , “lab on a chip” systems and the like. The methods can comprise any SPR-based assay format, including typical immunoassay formats. The immunoassay formats can include competitive and sandwich assays. Analyte capture agents can include antibodies, lectins, carbohydrates, polynucleotides, receptor proteins, and the like.
Melissa N Hasenbank from Ludington, MI, age ~36 Get Report