US Patent:
20120079613, Mar 29, 2012
Inventors:
Mathias Treier - Schwetzingen, DE
Maria Sakkou - Munich, DE
Petra Wiedmer - Potsdam, DE
Matthias Tschoep - Cincinnati OH, US
Assignee:
Deutsches Institut fur Ernahrungsforschung (DIFE) - Nuthetal
European Molecular Biology Laboratory (EMBL) - Heidelberg
International Classification:
A61K 39/395
C12N 15/12
C07K 16/18
A61K 38/17
A61K 31/711
C07K 1/14
A61P 3/04
C12N 15/85
A01K 67/027
C12N 5/10
C12P 21/02
C12P 19/34
C07K 14/00
A61K 31/7105
US Classification:
800 13, 530350, 536 235, 5303879, 514 48, 514 44 R, 4241391, 4353201, 435325, 435 691, 435 911
Abstract:
The present invention relates to the human homeobox transcription factor Bsx protein, nucleic acids encoding for said protein, vectors and cells comprising the nucleic acids, antibodies directed against Bsx, and methods for identifying compounds binding to Bsx, as well as to the use of proteins, nucleic acids, vectors, cells, and interacting compounds for treating obesity and related diseases.