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Mary Lynne Hedley

from Lexington, MA
Age ~62
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Also known as:
Mary L Hedley, Mary Lynne Urban, Marylynn L Hedley, Hedley Mary
Phone and address:
51 Follen Rd, Lexington, MA 02421
(781) 652-0200
Related to:
Tami L Urban-Schneider, 61
Connected to:
Caroline L Hedley, 47Catherine E Hedley, 63Deborah D Hedley, 71Jessica M Hedley, 39Maria K Hedley, 35Nathan L Hedley, 33Stephen Hedley, 57Tina J Hedley, 36Haley K Hedlin, 40Rachel A Hedlof, 55

Mary Hedley Phones & Addresses

  • 51 Follen Rd, Lexington, MA 02421 (781) 652-0200 (781) 674-0456
  • Belmont, MA
  • 46 Laurel St, Somerville, MA 02143
  • Cambridge, MA
  • Bedford, MA

Specialities

Commercial Real Estate Acquisitions • Commercial Leasing • Real Property Law • Business

Professional Records

Lawyers & Attorneys

Mary Hedley Photo 1

Mary Hedley - Lawyer

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Specialties:
Commercial Real Estate Acquisitions
Commercial Leasing
Real Property Law
Business
ISLN:
906586073
Admitted:
1982
University:
University of California at Berkeley, A.B., 1972
Law School:
Boalt Hall School of Law, University of California, J.D., 1982

License Records

Mary A. Hedley

License #:
001104-22 - Expired
Category:
Nursing
Issued Date:
Aug 7, 1960
Expiration Date:
Jan 25, 1973
Type:
Licensed Practical Nurse

Business Records

Name / Title
Company / Classification
Phones & Addresses
Mary L. Hedley
Vice-President
Mgi Pharma Biologics, Inc
Commercial Physical Research
35 Hartwell Ave, Lexington, MA 02421
(781) 862-1428
Mary Lynne Hedley
President, Founder
TESARO, Inc.
Pharmaceuticals · Mfg Pharmaceutical Preparations · Pharmaceutical Preparations
1000 Winter St, Waltham, MA
309 Waverley Oaks Rd, Waltham, MA 02452
(339) 970-0900

Publications

Us Patents

Immunomodulatory Peptides

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US Patent:
6509033, Jan 21, 2003
Filed:
Jun 7, 1995
Appl. No.:
08/475399
Inventors:
Robert Glen Urban - Cambridge MA
Roman M. Chicz - Jamaica Plain MA
Dario A. A. Vignali - Rainham, GB
Mary Lynne Hedley - Somerville MA
Lawrence J. Stern - Arlington MA
Jack L. Strominger - Lexington MA
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
A61K 9127
US Classification:
424450, 514 44, 536 231, 536 232, 536 235, 536 2351, 536 237, 536 2352, 536 2353, 536 234, 536 2372, 4353201
Abstract:
A purified preparation of a peptide consisting essentially of an amino acid sequence identical to that of a segment of a naturally-occurring human protein, said segment being of 10 to 30 residues in length, inclusive, wherein said peptide binds to a human major histocompatibility complex (MHC) class II allotype.

Immunogenic Peptides From The Hpv E7 Protein

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US Patent:
6582704, Jun 24, 2003
Filed:
Jan 12, 2001
Appl. No.:
09/759960
Inventors:
Robert G. Urban - Lexington MA
Roman M. Chicz - Belmont MA
Edward J. Collins - Carrboro NC
Mary Lynne Hedley - Lexington MA
Assignee:
Zycos Inc. - Lexington MA
International Classification:
A61K 3912
US Classification:
4242041, 4241861, 4241851, 435 691, 435 697, 536 2372, 530300, 530350
Abstract:
The invention provides immunogenic peptides from the HPV type 16 E7 protein that comprise overlapping class I restricted T cell epitopes. Also disclosed are methods of administering DNA molecules encoding these peptides to a host mammal.

Immunomodulatory Peptides

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US Patent:
6696061, Feb 24, 2004
Filed:
Jun 15, 1993
Appl. No.:
08/077255
Inventors:
Robert Glen Urban - Lexington MA
Roman M. Chicz - Belmont MA
Dario A. A. Vignali - Rainham, GB
Mary Lynne Hedley - Lexington MA
Lawrence J. Stern - Arlington MA
Jack L. Strominger - Lexington MA
Assignee:
President and Fellows of Harvard College - Cambridge MA
International Classification:
A61K 3817
US Classification:
4241851, 4242771, 4242781, 424810, 424450, 4242831, 514 2, 514885, 514 15, 514 14, 514 13, 514 12, 530806, 530328, 530327, 530326, 530325, 530324
Abstract:
A purified preparation of a peptide consisting essentially of an amino acid sequence identical to that of a segment of a naturally-occurring human protein, said segment being of 10 to 30 residues in length, inclusive, wherein said peptide binds to a human major histocompatibility complex (MHC) class II allotype.

Immunogenic Peptides From The Hpv E7 Protein

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US Patent:
7097843, Aug 29, 2006
Filed:
Jun 24, 2003
Appl. No.:
10/603062
Inventors:
Robert G. Urban - Lexington MA, US
Roman M. Chicz - Belmont MA, US
Edward J. Collins - Carrboro NC, US
Mary Lynne Hedley - Lexington MA, US
Assignee:
MGI Pharma Biologics, Inc. - Lexington MA
International Classification:
A61K 39/12
US Classification:
4242041, 4241861, 530300
Abstract:
The invention provides immunogenic peptides from the HPV type 16 E7 protein that comprise overlapping class I restricted T cell epitopes. Also disclosed are methods of administering DNA molecules encoding these peptides to a host mammal.

Α-Msh Related Compounds And Methods Of Use

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US Patent:
7169603, Jan 30, 2007
Filed:
Jul 16, 2001
Appl. No.:
09/906206
Inventors:
Mary Lynne Hedley - Lexington MA, US
Robert G. Urban - Lexington MA, US
Nazneen Aziz - Lexington MA, US
Hongmin Chen - Framingham MA, US
Bijan Etemad-Moghadam - Jamaica Plain MA, US
Peng Yin - Newton MA, US
Assignee:
MGI Pharma Biologics, Inc. - Lexington MA
International Classification:
C12N 1/00
C12P 21/02
C07H 21/00
US Classification:
4353201, 435 697, 435 691, 536 231, 536 234, 536 241
Abstract:
The invention provides polypeptides containing α-MSH that can be used to treat diseases characterized by inflammation and/or autoimmunity. Also included in the invention are α-MSH analogs and nucleic acids encoding polypeptides containing α-MSH and α-MSH analogs optionally linked to heterologous sequences. Also included in the invention are methods of delivering α-MSH containing peptides, α-MSH analogs, an DNA encoding α-MSH and α-MSH analogs.

Cyp1B1 Nucleic Acids And Methods Of Use

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US Patent:
7241742, Jul 10, 2007
Filed:
Oct 31, 2001
Appl. No.:
09/999686
Inventors:
Nazneen Aziz - Lexington MA, US
Mary Lynne Hedley - Lexington MA, US
Robert G. Urban - Lexington MA, US
Andrew J. Tomlinson - Wayland MA, US
Geoffrey Cole - Malden MA, US
Assignee:
MGI PHARMA Biologics, Inc. - Lexington MA
International Classification:
A01N 43/04
A01N 63/00
A61K 38/43
C07H 21/04
C12P 21/06
C12N 15/09
C12N 15/12
C12N 12/52
US Classification:
514 44, 424 932, 424 9321, 424 941, 435 691, 435 693, 4353201, 435440, 536 231, 536 232
Abstract:
The present invention provides nucleic acids containing transcriptional units that encode CYP1B1 polypeptides or portions thereof, wherein the transcriptional units lack sequences found in the untranslated region (UTR) of naturally occurring forms of the CYP1B1 transcript. The nucleic acids of the invention lack translational repressor elements and thus provide for a system of enhanced translation of the CYP1B1 polypeptide or portions thereof. Also disclosed are methods of administering nucleic acids to a mammal and use in the treatment of proliferative disorders or cancer.

Cyp1B1 Nucleic Acids And Methods Of Use

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US Patent:
8158594, Apr 17, 2012
Filed:
Apr 30, 2007
Appl. No.:
11/742278
Inventors:
Nazneen Aziz - Lexington MA, US
Mary Lynne Hedley - Lexington MA, US
Robert G. Urban - Lexington MA, US
Andrew J. Tomlinson - Wayland MA, US
Geoffrey Cole - Malden MA, US
Assignee:
Eisai Inc. - Woodcliff Lake NJ
International Classification:
A61K 48/00
US Classification:
514 44R
Abstract:
The present invention provides nucleic acids containing transcriptional units that encode CYP1B1 polypeptides or portions thereof, wherein the transcriptional units lack sequences found in the untranslated region (UTR) of naturally occurring forms of the CYP1B1 transcript. The nucleic acids of the invention lack translational repressor elements and thus provide for a system of enhanced translation of the CYP1B1 polypeptide or portions thereof. Also disclosed are methods of administering nucleic acids to a mammal and use in the treatment of proliferative disorders or cancer.

Microparticles For Delivery Of Nucleic Acid

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US Patent:
20020182258, Dec 5, 2002
Filed:
Jul 18, 2001
Appl. No.:
09/909460
Inventors:
Lynn Lunsford - Reading PA, US
David Putnam - Cambridge MA, US
Mary Hedley - Lexington MA, US
Assignee:
Zycos Inc., a Delaware corporation
International Classification:
A61K048/00
A61K009/50
US Classification:
424/499000, 514/044000, 435/320100
Abstract:
A preparation of microparticles made up of a polymeric matrix, a nucleic acid expression vector, and a lipid. The polymeric matrix includes one or more synthetic polymers having a solubility in water of less than about 1 mg/l. At least 90% of the microparticles have a diameter less than about 100 microns. The nucleic acid is either RNA, at least 50% of which is in the form of closed circles, or circular DNA plasmid molecules, at least 50% of which are supercoiled.
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Mary Lynne Hedley from Lexington, MA, age ~62 Get Report