Inventors:
Martin Mueller - Heidelberg, DE
John D. Nieland - Martinsried, DE
Markwin P. Velders - Forest Park IL
W. Martin Kast - Willowbrook IL
Assignee:
Loyola University of Chicago - Maywood IL
International Classification:
C07K 100
Abstract:
The present invention provides a chimeric protein including a first domain which includes at least a portion of a papillomavirus L1 or L2 protein and a second domain which includes a biotin-binding polypeptide. The invention also provides papillomaviruses, capsomeres, and VLPs including such chimeric proteins and a method for delivering biotinylated substances to cells using such reagents.