US Patent:
20230020999, Jan 19, 2023
Inventors:
Paul Rubinstein - Chicago IL, US
- Bothell WA, US
Ryan Alan HEISER - Bothell WA, US
Bryan Matthew GROGAN - Snohomish WA, US
Markus Puhlmann - Kirkland WA, US
International Classification:
A61K 47/68
A61K 47/65
A61K 47/64
A61P 31/18
Abstract:
The disclosure provides anti-CD30 antibody-drug conjugates and methods of using the same to increase CD4 T-cell lymphocyte count or treat 1-IIV infection. The disclosure also provides articles of manufacture or kits comprising said antibody drug-conjugates that bind to CD30 for increasing CD4 T-cell lymphocyte count or treating HIV infection.