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Mark Lehmann Bonyhadi

from Seattle, WA
Age ~71

Mark Bonyhadi Phones & Addresses

  • 3253 57Th Ave SW, Seattle, WA 98116
  • 27187 27Th St, Sammamish, WA 98075 (425) 391-2311
  • 27187 27Th St, Issaquah, WA 98075
  • Belmont, CA
  • San Mateo, CA
  • Kiona, WA
  • Oakland, CA
  • 27187 SE 27Th St, Issaquah, WA 98075 (425) 391-2311

Education

Degree: High school graduate or higher

Emails

Resumes

Resumes

Mark Bonyhadi Photo 1

Operating Partner

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Location:
3253 57Th St, Seattle, WA 98107
Industry:
Biotechnology
Work:
Qiming Venture Partners Usa
Operating Partner

No Affilliation May 2018 - Nov 2018
Future Former Chief Time For Exploration Officer

No Affiliation Apr 2018 - Nov 2018
Chief Time For Exploration Officer

Juno Therapeutics A Celgene Company Oct 2013 - Apr 2018
Vice President, Research Process Sciences

Juno Therapeutics, Inc. Oct 2013 - Apr 2018
Former Vice President Process Sciences and Head Research and Academic Affairs
Education:
University of California, Berkeley 1985 - 1990
Doctorates, Doctor of Philosophy, Immunology, Philosophy
Reed College 1979 - 1982
Bachelors, Bachelor of Arts, Biology
Catlin Gabel School 1972
Occidental College
Skills:
Biotechnology
Cell
Immunology
Life Sciences
Molecular Biology
Assay Development
Stem Cells
Cell Culture
Immunoassays
Fda
Cell Biology
Drug Discovery
Biochemistry
Technology Transfer
Lifesciences
Cancer
Commercialization
Biopharmaceuticals
Cell Therapy
Flow Cytometry
Oncology
Elisa
Clinical Development
Medical Devices
Antibodies
Regenerative Medicine
Dna
In Vitro
Immunotherapy
French
Cancer Immunotherapy
Languages:
French
Mark Bonyhadi Photo 2

Vice President Research

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Location:
2203 Airport Way south, Seattle, WA 98134
Industry:
Biotechnology
Work:
Xcyte Therapies
Vice President Research
Skills:
Lis

Publications

Us Patents

Simultaneous Stimulation And Concentration Of Cells

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US Patent:
6797514, Sep 28, 2004
Filed:
Sep 20, 2001
Appl. No.:
09/960264
Inventors:
Ronald Berenson - Mercer Island WA
Che Law - Shoreline WA
Mark Bonyhadi - Issaquah WA
Narinder Saund - Seattle WA
Stewart Craig - Issaquah WA
Alan Hardwick - Seattle WA
Dale Kalamasz - Redmond WA
David McMillen - Seattle WA
Assignee:
Xcyte Therapies, Inc. - Seattle WA
International Classification:
C12N 500
US Classification:
435325, 4353723, 436526
Abstract:
The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. In certain aspects methods for stimulating a population of cells such as T-cells, by simultaneous concentration and cell surface moiety ligation are provided by contacting the population of cells with a surface, that has attached thereto one or more agents that ligate a cell surface moiety and applying a force that predominantly drives cell concentration and cell surface moiety ligation, thereby inducing cell stimulation, cell surface moiety aggregation, and/or receptor signaling enhancement. Also provided are methods for producing phenotypically tailored cells, including T-cells for the use in diagnostics, drug discovery, and the treatment of a variety of indications, including cancer, viral infection, and immune related disorders. Compositions of cells having specific phenotypic properties produced by these processes are further provided.

Simultaneous Stimulation And Concentration Of Cells

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US Patent:
6867041, Mar 15, 2005
Filed:
Apr 26, 2002
Appl. No.:
10/133236
Inventors:
Ronald Berenson - Mercer Island WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Narinder Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Assignee:
XCYTE Therapies, Inc. - Seattle WA
International Classification:
C12N005/00
US Classification:
435377, 435325, 435326, 435375, 436526
Abstract:
The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and/or stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. In certain aspects methods for stimulating a population of cells such as T-cells, by simultaneous concentration and cell surface moiety ligation are provided by contacting the population of cells with a surface, that has attached thereto one or more agents that ligate a cell surface moiety and applying a force that predominantly drives cell concentration and cell surface moiety ligation, thereby inducing cell stimulation, cell surface moiety aggregation, and/or receptor signaling enhancement. Also provided are methods for producing phenotypically tailored cells, including T-cells for the use in diagnostics, drug discovery, and the treatment of a variety of indications, including cancer, viral infection, and immune related disorders. Compositions of cells having specific phenotypic properties produced by these processes are further provided.

Simultaneous Stimulation And Concentration Of Cells

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US Patent:
6905874, Jun 14, 2005
Filed:
Feb 26, 2001
Appl. No.:
09/794230
Inventors:
Ronald Berenson - Mercer Island WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Narinder Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Assignee:
XCYTE Therapies, Inc. - Seattle WA
International Classification:
C12N005/00
US Classification:
435375, 435325, 4353723, 436526
Abstract:
The present invention relates generally to methods for stimulating cells, and more particularly, to a novel method to concentrate and stimulate cells that maximizes stimulation and/or proliferation of such cells. In the various embodiments, cells are stimulated and concentrated with a surface yielding enhanced proliferation, cell signal transduction, and/or cell surface moiety aggregation. In certain aspects methods for stimulating a population of cells such as T-cells, by simultaneous concentration and cell surface moiety ligation are provided by contacting the population of cells with a surface, that has attached thereto one or more agents that ligate a cell surface moiety and applying a force that predominantly drives cell concentration and cell surface moiety ligation, thereby inducing cell stimulation, cell surface moiety aggregation, and/or receptor signaling enhancement. Also provided are methods for producing phenotypically tailored cells, including T-cells for the use in diagnostics, drug discovery, and the treatment of a variety of indications, including cancer, viral infection, and immune related disorders. Compositions of cells having specific phenotypic properties produced by these processes are further provided.

Activation And Expansion Of Cells

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US Patent:
7541184, Jun 2, 2009
Filed:
Jan 20, 2004
Appl. No.:
10/762210
Inventors:
Ronald J. Berenson - Mercer Island WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Narinder Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Harjinder Singh Chana - Issaquah WA, US
Assignee:
Invitrogen Corporation - Carlsbad CA
International Classification:
C12N 5/00
US Classification:
435375, 435325, 4353723
Abstract:
The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.

Activation And Expansion Of T Cells

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US Patent:
7572631, Aug 11, 2009
Filed:
Mar 2, 2005
Appl. No.:
11/070841
Inventors:
Ronald J Berenson - Mercer Island WA, US
Che Law - Shoreline WA, US
Mark Bonyhadi - Issaquah WA, US
Zahbea Saund - Seattle WA, US
Stewart Craig - Issaquah WA, US
Alan Hardwick - Seattle WA, US
Dale Kalamasz - Redmond WA, US
David McMillen - Seattle WA, US
Harjinder Singh Chana - Issaquah WA, US
Assignee:
Invitrogen Corporation - Carlsbad CA
International Classification:
C12N 5/00
US Classification:
435375, 435325, 4353723
Abstract:
The present invention relates generally to methods for activating and expanding cells, and more particularly, to a novel method to activate and/or stimulate cells that maximizes the expansion of such cells to achieve dramatically high densities. In the various embodiments, cells are activated and expanded to very high densities in a short period of time. In certain embodiments, cells are activated and expanded to very high numbers of cells in a short period of time. Compositions of cells activated and expanded by the methods herein are further provided.

Generation And Isolation Of Antigen-Specific T Cells

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US Patent:
7977095, Jul 12, 2011
Filed:
Oct 14, 2008
Appl. No.:
12/251224
Inventors:
Mark Bonyhadi - Issaquah WA, US
Dale Kalamasz - Redmond WA, US
Assignee:
Life Technologies Corporation - Carlsbad CA
International Classification:
C12N 5/08
C12N 5/00
US Classification:
4353723, 435375, 435405
Abstract:
The present invention relates generally to methods for generating, expanding, and isolating antigen-specific T cells. Compositions of antigen-specific T cells activated and expanded by the methods herein are further provided.

Methods For Eliminating At Least A Substantial Portion Of A Clonal Antigen-Specific Memory T Cell Subpopulation

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US Patent:
8617884, Dec 31, 2013
Filed:
Nov 26, 2008
Appl. No.:
12/324593
Inventors:
Ronald J Berenson - Mercer Island WA, US
Mark Bonyhadi - Sammamish WA, US
Dale Kalamasz - Redmond WA, US
Assignee:
Life Technologies Corporation - Carlsbad CA
International Classification:
C12N 5/00
US Classification:
435375, 435377, 435325, 4353723
Abstract:
The present invention relates generally to methods for stimulating T cells, and more particularly, to methods to eliminate undesired (e. g. , autoreactive, alloreactive, pathogenic) subpopulations of T cells from a mixed population of T cells, thereby restoring the normal immune repertoire of said T cells. The present invention also relates to compositions of cells, including stimulated T cells having restored immune repertoire and uses thereof.

T Cell Induced Tissue Repair And Regeneration

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US Patent:
20030022210, Jan 30, 2003
Filed:
Jun 3, 2002
Appl. No.:
10/162227
Inventors:
Mark Bonyhadi - Issaquah WA, US
Ron Berenson - Mercer Island WA, US
International Classification:
A61K045/00
C12Q001/68
C12N005/08
US Classification:
435/006000, 435/368000, 424/093700
Abstract:
The present invention relates to methods for the use of T cells or supernatants therefrom, and more particularly, activated T cells, in facilitating and/or regulating the differentiation, de-differentiation, maturation, organization, repair, and regeneration of various cells/tissues. Methods for inducing tissue repair and regeneration in vitro and in vivo are disclosed. The present invention also relates to compositions of cells, including activated T cells and/or cells resulting from the co-culture with activated T cells, and their use in inducing tissue repair and regeneration in vivo.
Mark Lehmann Bonyhadi from Seattle, WA, age ~71 Get Report