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Mark I Avigan

from Silver Spring, MD
Age ~74

Mark Avigan Phones & Addresses

  • 502 Hermleigh Rd, Silver Spring, MD 20902 (301) 681-5657

Work

Company: Evelyn K Mentari MD Address: 10903 New Hampshire Ave, Silver Spring, MD 20903 Phones: (301) 796-2279

Education

School / High School: McGill University Faculty Of Medicine 1977

Skills

Auditor • Quality Assurance

Languages

English

Awards

Healthgrades Honor Roll

Ranks

Certificate: Gastroenterology, 1983

Emails

Specialities

Gastroenterology

Professional Records

Medicine Doctors

Mark Avigan Photo 1

Dr. Mark I Avigan, Silver Spring MD - MD (Doctor of Medicine)

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Specialties:
Gastroenterology
Address:
Evelyn K Mentari MD
10903 New Hampshire Ave, Silver Spring, MD 20903
(301) 796-2279 (Phone)
Certifications:
Gastroenterology, 1983
Internal Medicine, 1980
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
McGill University Faculty Of Medicine
Graduated: 1977
Medical School
Royal Victoria Hospital
Graduated: 1978
Medical School
Georgetown University Va Hosps
Graduated: 1982
Medical School
Harper Hospital
Graduated: 1979
Medical School
Georgetown University Va Hosps
Graduated: 1983
Mark Avigan Photo 2

Mark Isaac Avigan

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Specialties:
Internal Medicine
Gastroenterology
Pediatrics
Education:
McGill University Faculty Of Medicine (1977)
Mark Avigan Photo 3

Mark Isaac Avigan, Silver Spring MD

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Specialties:
Gastroenterologist
Address:
10903 New Hampshire Ave, Silver Spring, MD 20903
Education:
McGill University, Faculty of Medicine - Doctor of Medicine
Georgetown University Hospital - Fellowship - Gastroenterology (Internal Medicine)
Georgetown University Hospital - Residency - Family Medicine
Harper University Hospital - Residency - Family Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine
American Board of Internal Medicine Sub-certificate in Gastroenterology (Internal Medicine)

Resumes

Resumes

Mark Avigan Photo 4

Mark Avigan

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Work:
Fda
Director Division of Drug Risk Evaluation, Food An
Skills:
Auditor
Quality Assurance

Business Records

Name / Title
Company / Classification
Phones & Addresses
Mark Avigan
Branch Manager
United States Department of Health & Human Services
Health Services
10903 New Hampshire, Silver Spring, MD 20993

Publications

Us Patents

Fuse Binding Protein And Cdna Therefor

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US Patent:
55807607, Dec 3, 1996
Filed:
Feb 22, 1993
Appl. No.:
8/021608
Inventors:
David L. Levens - Bethesda MD
Robert C. Duncan - Mt. Rainer MD
Mark I. Avigan - Silver Spring MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
C12P 1934
C07H 2104
C12N 510
C12N 1563
US Classification:
435 912
Abstract:
The Far Upstream Element (FUSE) of the human c-myc gene, stimulates expression in undifferentiated cells. A FUSE binding protein (FBP), also referred to as DROME (DNA-binding regulator of c-myc expression), is active in undifferentiated but not differentiated cell extracts. Cloned FBP exhibits the same DNA-binding specificity as the purified human protein and can trans-activate in a FUSE dependent manner. Sequence-specific binding to the FUSE oligonucleotide required at least two copies of a repeat-helix unit which defines a new DNA-binding motif. Expression of FBP mRNA declined in parallel with decreased FUSE binding activity upon differentiation suggesting transcriptional regulation of FBP. Features were identified in clones which suggested FBP is also regulated by RNA processing, translation and post-translational mechanisms.

Fuse Binding Protein And Method For Inhibiting Expression Of Fuse Binding Protein

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US Patent:
57340161, Mar 31, 1998
Filed:
Oct 4, 1996
Appl. No.:
8/726160
Inventors:
David L. Levens - Bethesda MD
Robert C. Duncan - Mt. Rainer MD
Mark I. Avigan - Silver Spring MD
Assignee:
The United States of America as represented by the Secretary of the
Department of Health and Human Services - Washington DC
International Classification:
C07K 1400
US Classification:
530324
Abstract:
The Far Upstream Element (FUSE) of the human c-myc gene stimulates expression in undifferentiated cells. A FUSE binding protein (FBP), also referred to as DROME (DNA-binding regulator of c-myc expression), is active in undifferentiated but not differentiated cell extracts. Cloned FBP exhibits the same DNA-binding specificity as the purified human protein and can trans-activate in a FUSE dependent manner. Sequence-specific binding to the FUSE oligonucleotide requires at least two copies of a repeat-helix unit which defines a new DNA-binding motif. Expression of FBP mRNA declined in parallel with decreased FUSE binding activity upon differentiation suggesting transcriptional regulation of FBP.
Mark I Avigan from Silver Spring, MD, age ~74 Get Report