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Mariusz Z Krawiec

from Marlborough, MA
Age ~61
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Also known as:
Marius Z Krawiec, Mariusz Kraweic
Related to:
Kaya S Krawiec
Connected to:
Amanda J Krawiec, 37Chad J Krawiec, 50Dominika Krawiec, 46Mariusz S Krawiec, 44Melanie M Krawiec, 51Sandra J Krawiec, 65Scott M Krawiec, 62Steven J Krawiec, 82Theresa M Krawiec, 71Adam S Krawitzky, 32

Mariusz Krawiec Phones & Addresses

  • Marlborough, MA
  • Brookfield, CT
  • Memphis, TN
  • Boston, MA
  • 7 Hay Barrick Rd, Whitehouse Station, NJ 08889 (908) 534-4289
  • Madison, WI
  • Dublin, OH
  • Easley, SC
  • Potsdam, NY
  • Fort Worth, TX
  • Lafayette, IN
  • 46 Littlefield Ln, Marlborough, MA 01752 (508) 485-5360

Education

Degree: Graduate or professional degree

Publications

Us Patents

Solid Forms Of N-[2,4-Bis(1,1-Dimethylethyl)-5-Hydroxyphenyl]-1,4-Dihydro-4-Oxoquinoline-3-Carboxamide

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US Patent:
8410274, Apr 2, 2013
Filed:
Jan 26, 2012
Appl. No.:
13/358778
Inventors:
Patricia Hurter - Harvard MA, US
William Rowe - Medford MA, US
Christopher Ryan Young - Waltham MA, US
Adriana Costache - Roslindale MA, US
Patrick R. Connelly - Harvard MA, US
Mariusz Krawiec - Marlborough MA, US
Yuchuan Gong - Waukegan IL, US
Yushi Feng - Zionsville IN, US
Martin Trudeau - Shannon, CA
Assignee:
Vertex Pharmaceuticals - Cambridge MA
International Classification:
C07D 215/38
US Classification:
546159, 546156, 514312
Abstract:
The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.

Solid Forms Of N-(4-(7-Azabicyclo[2.2.1]Heptan-7-Yl)-2-(Trifluorormethyl)Phenyl)-4-Oxo-5-(Trifluoromethyl)-1,4-Dihyroquinoline-3-Carboxamide

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US Patent:
8436014, May 7, 2013
Filed:
Oct 23, 2009
Appl. No.:
12/605266
Inventors:
Beili Zhang - San Diego CA, US
Mariusz Krawiec - Marlborough MA, US
Martyn Botfield - Concord MA, US
Peter D. J. Grootenhuis - San Diego CA, US
Fredrick Van Goor - San Diego CA, US
Assignee:
Vertex Pharmaceutical Incorporated - Cambridge MA
International Classification:
A61K 31/47
C07D 215/00
US Classification:
514312, 546156
Abstract:
The present invention relates to solid state forms, for example, crystalline forms of N-(4-(7-azabicyclo[2. 2. 1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, pharmaceutical compositions thereof, and methods therewith.

Solid Forms Of N-[2,4-Bis(1,1-Dimethylethyl)-5-Hydroxyphenyl]-1,4-Dihydro-4-Oxoquinoline-3-Carboxamide

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US Patent:
8471029, Jun 25, 2013
Filed:
Mar 21, 2011
Appl. No.:
13/053172
Inventors:
Sneha G. Arekar - Malden MA, US
Steven C. Johnston - Bolton MA, US
Mariusz Krawiec - Marlborough MA, US
Ales Medek - Winchester MA, US
Praveen Mudunuri - Waltham MA, US
Mark Jeffrey Sullivan - Framingham MA, US
Assignee:
Vertex Pharmaceutical Incorporated - Cambridge MA
International Classification:
C07D 215/56
US Classification:
546156
Abstract:
The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.

Solid Forms Of Gyrase Inhibitor (R)-1-Ethyl-3-[6-Fluoro-5-[2-(1-Hydroxy-1-Methyl-Ethyl)Pyrimidin-5-Yl]-7-(Tetrahydrofuran-2-Yl)-1H-Benzimidazol-2-Yl]Urea

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US Patent:
8476281, Jul 2, 2013
Filed:
Jan 13, 2012
Appl. No.:
13/349984
Inventors:
Dean Shannon - Milford MA, US
Brian Luisi - Somerville MA, US
Mariusz Krawiec - Marlborough MA, US
Anuj K. Kuldipkumar - Medford MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A01N 43/54
C07D 239/42
C07D 471/04
US Classification:
514256, 544333
Abstract:
The present application is directed to solid forms of compounds of formula I:.

Solid Forms Of Gyrase Inhibitor (R)-1-Ethyl-3-[5-[2-(1-Hydroxy-1-Methyl-Ethyl)Pyrimidin-5-Yl]-7-(Tetrahydrofuran-2-Yl)-1H-Benzimidazol-2-Yl]Urea

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US Patent:
8481552, Jul 9, 2013
Filed:
Jan 13, 2012
Appl. No.:
13/349845
Inventors:
Dean Shannon - Milford MA, US
Brian Luisi - Somerville MA, US
Yusheng Liao - Lexington MA, US
Mariusz Krawiec - Marlborough MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A01N 43/54
C07D 239/42
C07D 471/04
US Classification:
514256, 544333
Abstract:
The present application is directed to solid forms of compounds of formula (I):.

Solid Forms Of 3-(6-(1-(2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl) Cyclopropanecarboxamido)-3-Methylpyridin-2-Yl)Benzoic Acid

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US Patent:
8507534, Aug 13, 2013
Filed:
Dec 4, 2008
Appl. No.:
12/327902
Inventors:
Ali Keshavarz-Shokri - San Diego CA, US
Beili Zhang - San Diego CA, US
Mariusz Krawiec - Marlborough MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/443
C07D 405/12
US Classification:
514338, 5462837
Abstract:
The present invention relates to a substantially crystalline and free solid state form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Form I), pharmaceutical compositions thereof, and methods of treatment therewith.

Solid Forms Of 3-(6-(1-(2,2-Difluorobenzo[D][1,3]Dioxol-5-Yl) Cyclopropanecarboxamido)-3-Methylpyridin-2-Yl)Benzoic Acid

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US Patent:
8507687, Aug 13, 2013
Filed:
Apr 7, 2011
Appl. No.:
13/082156
Inventors:
Ali Keshavarz-Shokri - San Diego CA, US
Beili Zhang - San Diego CA, US
Mariusz Krawiec - Marlborough MA, US
Assignee:
Vertex Pharmaceuticals Incorporated - Cambridge MA
International Classification:
A61K 31/44
C07D 405/00
US Classification:
5462837, 514337
Abstract:
The present invention relates to a substantially a solid form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1, Solvate Form A and Compound 1, HCl Salt Form A), processes for making such forms, pharmaceutical compositions thereof, and methods of treatment therewith.

Solid Forms Of N-[2,4-Bis(1,1-Dimethylethyl)-5-Hydroxyphenyl]-1,4-Dihydro-4-Oxoquinoline-3-Carboxamide

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US Patent:
20110064811, Mar 17, 2011
Filed:
Dec 28, 2006
Appl. No.:
11/647505
Inventors:
Patricia Hurter - Harvard MA, US
William Rowe - Medford MA, US
Christopher R. Young - Waltham MA, US
Adriana Costache - Roslindale MA, US
Patrick R. Connelly - Harvard MA, US
Mariusz Krawiec - Marlborough MA, US
Yuchuan Gong - Waukegan IL, US
Yushi Feng - Malden MA, US
Martin Trudeau - Cambridge MA, US
International Classification:
A61K 9/14
C07D 215/56
A61K 31/47
A61P 3/10
A61P 11/00
A61P 7/10
A61P 3/00
A61P 35/00
A61P 25/28
A61P 25/16
A61P 27/04
A61P 7/00
US Classification:
424489, 546156, 514312
Abstract:
The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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Mariusz Z Krawiec from Marlborough, MA, age ~61 Get Report