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Marina K Roell

from Concord, CA
Age ~67

Marina Roell Phones & Addresses

  • 4484 Pitch Pine Ct, Concord, CA 94521 (925) 825-2576
  • 2864 Foskett Ave, Concord, CA 94520 (925) 825-2576
  • Sioux Falls, SD
  • Richmond, CA
  • Goleta, CA
  • Warrenton, VA
  • 2864 Foskett Ave, Concord, CA 94520 (925) 890-7769

Work

Company: Xoma Position: Director, discovery program

Skills

Antibodies • Monoclonal Antibodies • Molecular Biology • Assay Development • Phage Display • Elisa • Drug Discovery • Cell Culture • Protein Purification • Protein Chemistry • Immunology • High Throughput Screening • Lifesciences • Cell Biology • Protein Engineering • Purification • Lims • Surface Plasmon Resonance • Research Informatics

Industries

Biotechnology

Resumes

Resumes

Marina Roell Photo 1

Marina Roell

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Location:
San Francisco, CA
Industry:
Biotechnology
Work:
Xoma
Director, Discovery Program

Xoma
Director, Molecular Interactions and Research Informatics
Skills:
Antibodies
Monoclonal Antibodies
Molecular Biology
Assay Development
Phage Display
Elisa
Drug Discovery
Cell Culture
Protein Purification
Protein Chemistry
Immunology
High Throughput Screening
Lifesciences
Cell Biology
Protein Engineering
Purification
Lims
Surface Plasmon Resonance
Research Informatics

Publications

Us Patents

Method Of Treating Or Preventing An Il-1 Related Disease Or Condition

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US Patent:
7582742, Sep 1, 2009
Filed:
Jul 18, 2008
Appl. No.:
12/218914
Inventors:
Linda Masat - Oakland CA, US
Mary Haak-Frendscho - Newark CA, US
Gang Chen - San Diego CA, US
Arnold Horwitz - San Leandro CA, US
Marina Roell - Concord CA, US
Assignee:
XOMA Technology Ltd. - Berkeley CA
International Classification:
C12N 5/10
C12N 15/13
C12N 15/63
US Classification:
536 2353, 435325, 4352523, 4353201
Abstract:
Methods of treating or preventing an IL-1 related disease or condition in a mammal comprising administering an effective amount of an IL-1β binding antibody or IL-1β binding fragment thereof. An IL-1β binding antibody or IL-1β binding fragment thereof is provided comprising the amino acid sequence of SEQ ID NO:28, and related nucleic acids, vectors, cells, and compositions, and a method of preparing an affinity matured IL-1β binding polypeptide is provided. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

Method Of Treating An Il-1 Related Inflammatory Disease Or Condition

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US Patent:
7695717, Apr 13, 2010
Filed:
Jul 18, 2008
Appl. No.:
12/218997
Inventors:
Linda Masat - Oakland CA, US
Mary Haak-Frendscho - Newark CA, US
Gang Chen - San Diego CA, US
Arnold Horwitz - San Leandro CA, US
Marina Roell - Concord CA, US
Assignee:
XOMA Technology Ltd. - Berkeley CA
International Classification:
A61K 39/395
US Classification:
4241411, 4241451, 4241391
Abstract:
Methods of treating or preventing an IL-1 related disease or condition in a mammal comprising administering an effective amount of an IL-1β binding antibody or IL-1β binding fragment thereof. An IL-1β binding antibody or IL-1β binding fragment thereof is provided comprising the amino acid sequence of SEQ ID NO:28, and related nucleic acids, vectors, cells, and compositions, and a method of preparing an affinity matured IL-1β binding polypeptide is provided. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

Il1-Β Binding Antibodies And Fragments Thereof

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US Patent:
7744865, Jun 29, 2010
Filed:
May 11, 2009
Appl. No.:
12/463741
Inventors:
Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US
Assignee:
Xoma Technology Ltd. - Berkeley CA
International Classification:
C07K 16/24
A61K 39/395
US Classification:
424 852, 5303871, 5303881
Abstract:
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 8 and SEQ ID NO: 9, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

Il-1Β Binding Antibodies And Binding Fragments Thereof

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US Patent:
7744866, Jun 29, 2010
Filed:
May 11, 2009
Appl. No.:
12/463844
Inventors:
Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US
Assignee:
XOMA Technology Ltd. - Berkeley CA
International Classification:
C07K 16/24
A61K 39/395
US Classification:
424 852, 5303871, 5303881
Abstract:
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 26 and SEQ ID NO: 11, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

Method Of Treating An Il-1 Related Autoimmune Disease Or Condition

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US Patent:
7829093, Nov 9, 2010
Filed:
May 11, 2009
Appl. No.:
12/464006
Inventors:
Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US
Assignee:
Xoma Technology Ltd. - Berkeley CA
International Classification:
A61K 39/395
US Classification:
4241451, 4241301, 4241391, 4241411, 514885
Abstract:
Methods of treating or preventing an IL-1 related disease or condition in a mammal comprising administering an effective amount of an IL-1β binding antibody or IL-1β binding fragment thereof. An IL-1β binding antibody or IL-1β binding fragment thereof is provided comprising the amino acid sequence of SEQ ID NO: 15 and SEQ ID NO: 11, and related nucleic acids, vectors, cells, and compositions, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

Method Of Treating An Il-1 Related Cancer

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US Patent:
7829094, Nov 9, 2010
Filed:
May 11, 2009
Appl. No.:
12/464061
Inventors:
Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US
Assignee:
Xoma Technology Ltd. - Berkeley CA
International Classification:
A61K 39/395
US Classification:
4241451, 4241301, 4241391, 4241411, 514885
Abstract:
Methods of treating or preventing an IL-1 related disease or condition in a mammal comprising administering an effective amount of an IL-1β binding antibody or IL-1β binding fragment thereof. An IL-1β binding antibody or IL-1β binding fragment thereof is provided comprising the amino acid sequence of SEQ ID NO: 15 and SEQ ID NO: 11, and related nucleic acids, vectors, cells, and compositions, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

Il-1Β Binding Antibodies And Fragments Thereof

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US Patent:
7943121, May 17, 2011
Filed:
May 12, 2009
Appl. No.:
12/464381
Inventors:
Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US
Assignee:
XOMA Technology Ltd. - Berkeley CA
International Classification:
C07K 16/24
A61K 39/395
US Classification:
424 852, 5303871, 5303881
Abstract:
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 2, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.

Method Of Treating An Il-1 Related Coronary Condition

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US Patent:
7988968, Aug 2, 2011
Filed:
May 12, 2009
Appl. No.:
12/464323
Inventors:
Linda Masat - Walnut Creek CA, US
Mary Haak-Frendscho - Newark CA, US
Arnold H. Horwitz - San Leandro CA, US
Gang Chen - San Diego CA, US
Marina Roell - Concord CA, US
Assignee:
Xoma Technology Ltd. - Berkeley CA
International Classification:
A61K 39/395
US Classification:
4241451, 4241301, 4241391, 4241411
Abstract:
An IL-1β binding antibody or IL-1β binding fragment thereof comprising the amino acid sequence of SEQ ID NO: 2, and related nucleic acids, vectors, cells, and compositions, as well as method of using same to treat or prevent a disease, and a method of preparing an affinity matured IL-1β binding polypeptide. IL-1β binding antibodies or IL-1β binding fragments thereof are provided which have desirable affinity and potency.
Marina K Roell from Concord, CA, age ~67 Get Report