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Maria S Fardis

from San Carlos, CA
Age ~57

Maria Fardis Phones & Addresses

  • 105 Aberdeen Dr, San Carlos, CA 94070 (650) 551-0683 (619) 787-1230
  • Hayward, CA
  • Dallas, TX
  • Mountain View, CA
  • San Jose, CA
  • Urbana, IL
  • 105 Aberdeen Dr, San Carlos, CA 94070

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Resumes

Resumes

Maria Fardis Photo 1

San Carlos, California

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Location:
San Carlos, CA
Industry:
Biotechnology
Work:
Kartos Therapeutics
Non Executive Board Member

Iovance Biotherapeutics
President and Chief Executive Officer

Acerta Pharma Jan 2015 - Mar 2016
Chief Operating Officer

Pharmacyclics Mar 2013 - Dec 2014
Chief of Oncology Operations and Alliances

Pharmacyclics Sep 2012 - Mar 2013
Executive Vice President of Operations and Alliances
Education:
Golden Gate University 2004 - 2007
Master of Business Administration, Masters, Management
University of California, Berkeley 1993 - 1998
Doctorates, Doctor of Philosophy, Organic Chemistry
University of Illinois at Urbana - Champaign 1989 - 1992
Bachelors, Bachelor of Science, Organic Chemistry
Skills:
Clinical Development
Biotechnology
Oncology
Pharmaceutical Industry
Clinical Trials
Drug Development
Clinical Research
Ind
Biopharmaceuticals
Project Management
Cancer
Cro
Drug Discovery
Gcp
Fda
Cross Functional Team Leadership
Gmp
Lifesciences
Regulatory Submissions
Regulatory Affairs
Infectious Diseases
Medical Devices
Technology Transfer
Commercialization
Immunology
Medicinal Chemistry
Validation
Clinical Operations
Glp
Hematology
Ctms
21 Cfr Part 11
Medical Affairs
Executive Management
Edc
Pharmaceutics
Therapeutic Areas
Protocol
Formulation
Sop
Vaccines
Medical Writing
Clinical Monitoring
Change Control
Ich Gcp
Pharmacovigilance
Clinical Data Management
Neurology
Gxp
Capa
Interests:
Science and Technology
Maria Fardis Photo 2

Maria Fardis

View page
Location:
San Carlos, CA
Industry:
Biotechnology
Skills:
Biotechnology
Ind
Clinical Development
Clinical Trials
Clinical Research
Project Management
Pharmaceutical Industry
Oncology
Lifesciences
Gmp
Cancer
Drug Discovery
Medicinal Chemistry
Gcp
Regulatory Affairs
Ctms
Drug Development
Cross Functional Team Leadership
Cro
Biopharmaceuticals
Fda
Formulation
Infectious Diseases
Regulatory Submissions
Technology Transfer
Commercialization
Validation
Sop
21 Cfr Part 11
Clinical Operations
Glp
Medical Affairs
Executive Management
Immunology
Vaccines
Therapeutic Areas
Hematology
Pharmacovigilance
Protocol
Medical Writing
Edc
Clinical Monitoring
Change Control
Medical Devices
Clinical Data Management
Pharmaceutics
Ich Gcp
Neurology
Gxp
Capa

Publications

Us Patents

Polyketide Derivatives

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US Patent:
6624302, Sep 23, 2003
Filed:
Dec 27, 2002
Appl. No.:
10/331047
Inventors:
Daniel Chu - Santa Clara CA
Maria Fardis - San Carlos CA
Chaitan Khosla - Palo Alto CA
Christopher Reeves - Orinda CA
Daniel Santi - San Francisco CA
Andreas Schirmer - Hayward CA
Assignee:
Kosan Biosciences, Inc. - Hayward CA
International Classification:
C07D49816
US Classification:
540456
Abstract:
The present invention relates to novel polyketides, host cells that produce the novel compounds, and methods fort their use. The compounds of the present invention are cyclic polyketides (also referred to as a âmacrolidesâ or âmacrolactonesâ) that include as part of their structure and bind to a FK binding protein wherein R and R are each selected from the group consisting of hydrogen, methyl, ethyl, and methoxy, provided that at least one of R and R is hydrogen, methyl, or ethyl. As will be explained in greater detail below, the compounds of the present invention have properties such as favorable P450 enzyme activity profiles that are desirable for use of these compounds as drugs.

Dabderivatives Of Lipopeptide Antibiotics And Methods Of Making And Using The Same

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US Patent:
7125844, Oct 24, 2006
Filed:
Jan 2, 2003
Appl. No.:
10/336641
Inventors:
Maria Fardis - San Carlos CA, US
Dale R. Cameron - Richmond, CA
Vincent A. Boyd - Vancouver, CA
Assignee:
Migenix Inc. - Vancouver
International Classification:
A61K 38/00
US Classification:
514 9
Abstract:
The present invention provides Dabderivatives of amphomycin-type lipopeptide antibiotics that display antimicrobial activity against Gram-positive bacteria, methods and intermediates for synthesizing such compounds, and methods of using the compounds in a variety of contexts, including in the treatment and prevention of infections.

Pre-Organized Tricyclic Integrase Inhibitor Compounds

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US Patent:
7253180, Aug 7, 2007
Filed:
Oct 16, 2003
Appl. No.:
10/687373
Inventors:
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Maria Fardis - San Carlos CA, US
Haolun Jin - Foster City CA, US
Choung U. Kim - San Carlos CA, US
Laura N. Schacherer - San Francisco CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A01N 43/42
A61K 31/44
C07D 471/00
C07D 491/00
C07D 498/00
US Classification:
514292, 546 23, 546 84
Abstract:
Tricyclic compounds according to the structure below, protected intermediates thereof, and methods for inhibition of HIV-integrase are disclosed. Aand Aare moieties forming a five, six, or seven membered ring. L is a bond or a linker connecting a ring atom of Ar to N. X is O, S, or substituted nitrogen. Ar is aryl or heteroaryl. Q is N, NR, or CR. The aryl carbons may be independently substituted with substituents other than hydrogen. The compounds may include prodrug moieties covalently attached at any site.

Phosphonate Analogs For Treating Metabolic Diseases

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US Patent:
7407965, Aug 5, 2008
Filed:
Apr 26, 2004
Appl. No.:
10/832817
Inventors:
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Maria Fardis - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Steven Krawczyk - San Carlos CA, US
Hyung-Jung Pyun - Freemont CA, US
William J. Watkins - Sunnyvale CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/505
C07F 9/02
US Classification:
514275, 544243
Abstract:
The invention is related to phosphorus substituted compounds with activity for treating metabolic diseases and/or disorders, e. g. , diabetes and hypercholesterolemia, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Kinase Inhibitory Phosphonate Analogs

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US Patent:
7417055, Aug 26, 2008
Filed:
Apr 26, 2004
Appl. No.:
10/832811
Inventors:
Carina Cannizzaro - San Mateo CA, US
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Manoj Desai - Pleasant Hill CA, US
Maria Fardis - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Richard L. Mackman - Millbrae CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
William J. Watkins - Sunnyvale CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/44
C07D 239/72
US Classification:
514306, 544293
Abstract:
The invention is related to phosphorus substituted kinase inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Purine Nucleoside Phosphorylase Inhibitory Phosphonate Compounds

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US Patent:
7427624, Sep 23, 2008
Filed:
Apr 26, 2004
Appl. No.:
10/832816
Inventors:
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Maria Fardis - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Adrian S. Ray - San Mateo CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
William J. Watkins - Sunnyvale CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/517
C07D 487/00
US Classification:
5142661, 544280, 544232
Abstract:
The invention is related to phosphorus substituted purine nucleoside phosphorylase inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Inosine Monophosphate Dehydrogenase Inhibitory Phosphonate Compounds

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US Patent:
7427636, Sep 23, 2008
Filed:
Apr 26, 2004
Appl. No.:
10/832829
Inventors:
Carina Cannizzaro - San Mateo CA, US
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Maria Fardis - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Hyung-Jung Pyun - Freemont CA, US
William J. Watkins - Sunnyvale CA, US
Jennifer R. Zhang - Foster City CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/42
C07D 263/30
US Classification:
514374, 514 79, 548235, 548112
Abstract:
The invention is related to phosphorus substituted IMPDH inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Antiviral Phosphonate Analogs

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US Patent:
7429565, Sep 30, 2008
Filed:
Apr 26, 2004
Appl. No.:
10/832815
Inventors:
Constantine G. Boojamra - San Francisco CA, US
Carina Cannizzaro - San Mateo CA, US
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Aesop Cho - Mountain View CA, US
Lee S. Chong - Newark CA, US
Maria Fardis - San Carlos CA, US
Haolun Jin - Foster City CA, US
Ralph F. Hirschmann - Philadelphia PA, US
Alan X. Huang - San Mateo CA, US
Choung U. Kim - San Carlos CA, US
Thorsten Kirschberg - Belmont CA, US
Christopher P. Lee - San Francisco CA, US
William A. Lee - Los Altos CA, US
Richard L. Mackman - Millbrae CA, US
David Y. Markevitch - Los Angeles CA, US
David A. Oare - Belmont CA, US
Vidya K. Prasad - Burlingame CA, US
Hyung-Jung Pyun - Freemont CA, US
Adrian S. Ray - San Mateo CA, US
Rosemarie Sherlock - Palo Alto CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
William J. Watkins - Sunnyvale CA, US
Jennifer R. Zhang - Foster City CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 38/00
C07D 267/22
US Classification:
514 9, 514 10, 514 11, 514 18, 514 19, 540455, 540460
Abstract:
The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
Maria S Fardis from San Carlos, CA, age ~57 Get Report