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Maia V Vinogradova

from San Francisco, CA
Age ~54
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Also known as:
Maia Valentinovna Vinogradova, Maia M Vinogradova, Maria Vinogradova, Maia V Vinogravoda
Phone and address:
125 Cambon Dr, San Francisco, CA 94132
(415) 587-1344
Related to:
Nadezhda Mayster, 29
Connected to:
Dmitri V Vinogradov, 44Dmitry Vinograd, 70James M Vinograd, 44Javier Vinograd, 56Jeanny L Vinogradov, 41Liliya Vinogradov, 63Olga Vinogradova, 61Valeria Vinogradova, 36Victor Vinogradov, 69Yefim Vinogradsky, 73

Maia Vinogradova Phones & Addresses

  • 125 Cambon Dr, San Francisco, CA 94132 (415) 587-1344
  • 710 Gonzalez Dr, San Francisco, CA 94132 (415) 587-1344
  • Moraga, CA
  • Nice, CA
  • Lake La, CA

Resumes

Resumes

Maia Vinogradova Photo 1

Senior Director

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Location:
2079 Ascot Dr, Moraga, CA 94556
Industry:
Research
Work:
Genentech since Jul 2012
SRA
UCSF Feb 1999 - Jul 2012
Research scientist
Ste-Justine Hospital, Montreal University Dec 1995 - Dec 1996
Post Doctoral Fellow
Education:
Moscow State University 1995
Ph.D, Enzyme kinetics and Biochemistry Moscow State University 1987 - 1992
Skills:
Biochemistry
Structural Biology
Protein Purification
Protein Expression
Cell Biology
Molecular Biology
X Ray Crystallography
Purification
Protein Chemistry
Crystallography
Molecular Cloning
Protein Engineering
Western Blotting
Assay Development
Drug Discovery
Cell
Cancer
Elisa
Microscopy
Mass Spectrometry
Pcr
Hplc
Immunoprecipitation
Dsf
Chemical Modification of Proteins
Transfection
Sds Page
Flow Cytometry
Mutagenesis
Immunohistochemistry
Octet Red
Cell Proliferation Assays
Languages:
English
Maia Vinogradova Photo 2

Associate Specialist At Ucsf

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Position:
associate specialist at UCSF
Location:
San Francisco Bay Area
Industry:
Research
Work:
UCSF
associate specialist

Publications

Us Patents

Coexpression And Purification Method Of Conditionally Activated Binding Proteins

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US Patent:
20210309756, Oct 7, 2021
Filed:
Aug 9, 2019
Appl. No.:
17/266065
Inventors:
- Brisbane CA, US
Maia VINOGRADOVA - Moraga CA, US
Ying ZHU - Brisbane CA, US
International Classification:
C07K 16/30
C07K 16/28
Abstract:
Provided herein are methods for co-expressing and purifying conditionally activated binding proteins such as hemi-COBRAs.

Constrained Conditionally Activated Binding Proteins

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US Patent:
20200347132, Nov 5, 2020
Filed:
Mar 5, 2020
Appl. No.:
16/810770
Inventors:
- Brisbane CA, US
Robert B. DUBRIDGE - Belmont CA, US
Maia VINOGRADOVA - Moraga CA, US
Anand PANCHAL - San Francisco CA, US
International Classification:
C07K 16/28
A61P 35/00
Abstract:
The invention relates to COnditional Bispecific Redirected Activation constructs, or COBRAs, that are administered in an active pro-drug format. Upon exposure to tumor proteases, the constructs are cleaved and activated, such that they can bind both tumor target antigens (TTAs) as well as CD3, thus recruiting T cells expressing CD3 to the tumor, resulting in treatment. In some embodiments, the tumor target antigen is B7H3.

Constrained Conditionally Activated Binding Proteins

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US Patent:
20190076524, Mar 14, 2019
Filed:
Sep 7, 2018
Appl. No.:
16/124556
Inventors:
- Brisbane CA, US
Robert B. Dubridge - Belmont CA, US
Maia Vinogradova - Moraga CA, US
Anand Panchal - San Francisco CA, US
International Classification:
A61K 39/395
A61P 35/00
C07K 16/46
Abstract:
The invention relates to COnditional Bispecific Redirected Activation constructs, or COBRAs, that are administered in an active pro-drug format. Upon exposure to tumor proteases, the constructs are cleaved and activated, such that they can bind both tumor target antigens (TTAs) as well as CD3, thus recruiting T cells expressing CD3 to the tumor, resulting in treatment.

Inducible Binding Proteins And Methods Of Use

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US Patent:
20180134789, May 17, 2018
Filed:
Oct 6, 2017
Appl. No.:
15/727423
Inventors:
- Brisbane CA, US
Robert B. DUBRIDGE - Belmont CA, US
Holger WESCHE - San Francisco CA, US
Luke EVNIN - San Francisco CA, US
Jeanmarie GUENOT - San Francisco CA, US
Anand PANCHAL - San Francisco CA, US
Maia VINOGRADOVA - Moraga CA, US
International Classification:
C07K 16/28
C07K 16/18
A61P 37/02
A61P 37/08
A61P 31/00
A61P 31/12
A61P 33/00
A61P 37/06
A61P 35/00
C07K 16/30
Abstract:
Provided herein are conditionally activated polypeptide constructs comprising a protease-activated domain binding to CD3, at least one half-life extension domain, and two or more domains binding to one or more target antigens. Also provided are pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such polypeptide constructs. Also disclosed are methods of using the disclosed polypeptide constructs in the prevention, and/or treatment diseases, conditions and disorders.

Tetrahydroisoquinoline Estrogen Receptor Modulators And Uses Thereof

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US Patent:
20170320871, Nov 9, 2017
Filed:
Apr 7, 2017
Appl. No.:
15/481757
Inventors:
- South San Francisco CA, US
Jun Liang - Palo Alto CA, US
Daniel Fred Ortwine - San Ramon CA, US
Maia Vinogradova - South San Francisco CA, US
Xiaojing Wang - Foster City CA, US
Jason Zbieg - South San Francisco CA, US
Birong Zhang - Union City CA, US
Tao Wang - Shanghai, CN
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07D 471/04
C07D 401/14
A61K 31/55
A61K 31/4725
A61K 31/5377
A61K 31/4745
C07D 403/12
C07D 401/12
Abstract:
Described herein are tetrahydroisoquinoline compounds with estrogen receptor modulation activity or function having the Formula I structure:
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Maia V Vinogradova from San Francisco, CA, age ~54 Get Report