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Madan Rajyalakshmi Katragadda

from Acton, MA
Age ~48
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Also known as:
Mada Katragadda
Phone and address:
5 Aspen Ln, Acton, MA 01720
(781) 398-2202
Related to:
Gnanalakshmi S Katragadda, 34Indira D Katragadda, 73
Connected to:
Jyothi Katragadda, 45Kishore Katragadda, 33Lakshmikanth Katragadda, 46Naveen V Katragadda, 42Siva K Katragadda, 42Tilak B Katragadda, 52George D Katrantzos, 39Jason C Katraouzos, 50Lanette L Katre, 52Esther Katri, 34

Madan Katragadda Phones & Addresses

  • 5 Aspen Ln, Acton, MA 01720 (781) 398-2202
  • Bedford, MA
  • 188 Ridge Ln, Waltham, MA 02452 (781) 398-2202 (781) 893-0792
  • 188 Ridge Ln #14, Waltham, MA 02452 (781) 398-2202
  • 214 Fox Haven Ct, O Fallon, MO 63368 (636) 265-0860
  • Chesterfield, MO
  • Ypsilanti, MI
  • Temple, TX
  • Philadelphia, PA
  • Storrs Mansfield, CT
  • Buzzards Bay, MA

Publications

Us Patents

Rage Fusion Protein Compositions And Methods Of Use

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US Patent:
20130142792, Jun 6, 2013
Filed:
Oct 19, 2010
Appl. No.:
13/062395
Inventors:
Jeffrey C. Webster - Jamestown NC, US
Gregory T. Bleck - Cross Plains WI, US
Madan Katragadda - Bedford MA, US
Manoj Rajadhyaksha - Colchester CT, US
Bernard N. Violand - Wildwood MO, US
Jo-Ann Wentland - Pawcatuck CT, US
Linda Marie Rothlein - Greensboro NC, US
International Classification:
C07K 14/705
C07K 16/00
US Classification:
4241341, 5303873, 536 234, 4353201, 435325, 435361, 435369, 435354, 435367, 435352, 435365, 435370, 435371
Abstract:
Disclosed are fusion proteins comprising a RAGE polypeptide, wherein the RAGE polypeptide comprises a fragment of a mammalian wild type RAGE peptide and at least one point mutation in the RAGE polypeptide portion of the fusion protein relative to the wild type RAGE peptide. The point mutation may remove and/or alter a glycosylation site or an enzyme cleavage site. Also disclosed are nucleic acids encoding such proteins as well as methods of using such proteins for treating RAGE-mediated pathologies.

Multifunctional Molecules That Bind To Calreticulin And Uses Thereof

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US Patent:
20210380670, Dec 9, 2021
Filed:
Aug 13, 2021
Appl. No.:
17/402329
Inventors:
- Cambridge MA, US
Ilaria Lamberto - Arlington MA, US
Seng-Lai Tan - Sudbury MA, US
Jonathan Hsu - Waltham MA, US
Brian Edward Vash - Cambridge MA, US
Nidhi Malhotra - Boston MA, US
Madan Katragadda - Acton MA, US
John Leonard Herrmann - Winchester MA, US
Stephanie J. Maiocco - Arlington MA, US
International Classification:
C07K 16/18
C07K 16/28
A61K 39/395
A61P 35/00
Abstract:
Multifunctional molecules that include i) an antigen binding domain that binds to a calreticulin protein; and one, two or all of: (ii) an immune cell engager (e.g., chosen from an NK cell engager, a T cell engager, a B cell engager, a dendritic cell engager, or a macrophage cell engager); (iii) a cytokine molecule; and/or (iv) a stromal modifying moiety are disclosed. Additionally disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.

Multifunctional Molecules That Bind To T Cell Related Cancer Cells And Uses Thereof

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US Patent:
20210380682, Dec 9, 2021
Filed:
Aug 13, 2021
Appl. No.:
17/402325
Inventors:
- Cambridge MA, US
Nidhi Malhotra - Boston MA, US
Madan Katragadda - Acton MA, US
Seng-Lai Tan - Sudbury MA, US
Jonathan Hsu - Waltham MA, US
Brian Edward Vash - Cambridge MA, US
Stephanie J. Maiocco - Arlington MA, US
Peter Marek - Hudson MA, US
Gurkan Guntas - Newton MA, US
International Classification:
C07K 16/28
A61P 35/00
Abstract:
Multifunctional molecules that include i) an antigen binding domain that binds to a T cell receptor beta chain constant domain 1 or T cell receptor beta chain constant domain 2; and one, two or all of: (ii) an immune cell engager (e.g., chosen from an NK cell engager, a T cell engager, a B cell engager, a dendritic cell engager, or a macrophage cell engager); (iii) a cytokine molecule or cytokine inhibitor molecule; (iv) a death receptor signal enhancer; and/or (v) a stromal modifying moiety are disclosed. Additionally disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.

Multifunctional Molecules That Bind To T Cells And Uses Thereof To Treat Autoimmune Disorders

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US Patent:
20210380691, Dec 9, 2021
Filed:
Aug 13, 2021
Appl. No.:
17/402318
Inventors:
- Cambridge MA, US
Seng-Lai Tan - Sudbury MA, US
Jonathan Hsu - Waltham MA, US
Brian Edward Vash - Cambridge MA, US
Stephanie J. Maiocco - Arlington MA, US
Nidhi Malhotra - Boston MA, US
Madan Katragadda - Acton MA, US
International Classification:
C07K 16/28
G01N 33/574
Abstract:
Multifunctional molecules that include i) an antigen binding domain that binds to a TCR variable beta chain (TCRBV) antigen; and one, two or all of: (ii) an immune cell engager (e.g., chosen from an NK cell engager, a T cell engager, a B cell engager, a dendritic cell engager, or a macrophage cell engager); (iii) a cytokine molecule or cytokine inhibitor molecule; and/or (iv) a death receptor signal enhancer. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, and methods of treating autoimmune diseases using the aforesaid molecules.

Antibody Molecules That Bind To Nkp30 And Uses Thereof

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US Patent:
20210371523, Dec 2, 2021
Filed:
Aug 13, 2021
Appl. No.:
17/402320
Inventors:
- Cambridge MA, US
Nidhi Malhotra - Boston MA, US
Madan Katragadda - Acton MA, US
Brian Edward Vash - Cambridge MA, US
Stephanie J. Maiocco - Arlington MA, US
International Classification:
C07K 16/28
A61K 45/06
A61K 39/395
Abstract:
Antibody molecules that specifically bind to NKp30 are disclosed. The anti-NKp30 antibody molecules can be used to treat, prevent and/or diagnose cancerous, autoimmune or infectious conditions and disorders.

Antibodies And Antibody-Drug Conjugates Specific For Cd123 And Uses Thereof

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US Patent:
20200283536, Sep 10, 2020
Filed:
Oct 16, 2018
Appl. No.:
16/758124
Inventors:
- New York NY, US
Madan KATRAGADDA - Acton MA, US
Lawrence Nathan TUMEY - Vestal NY, US
Assignee:
Pfizer Inc. - New York NY
International Classification:
C07K 16/28
A61K 47/68
C12N 15/63
A61P 35/00
Abstract:
The present invention provides antibodies that specifically bind to CD123. The invention further relates to immunoconjugates (e.g., antibody-drug conjugates, or ADCs) comprising such antibodies, antibody encoding nucleic acids, and methods of obtaining such antibodies. The invention further relates to therapeutic methods for use of these antibodies and ADCs for the treatment of a condition associated with cells expressing CD123 (e.g., cancer or autoimmune disease).

Antibodies Specific For Gucy2C And Uses Thereof

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US Patent:
20200010566, Jan 9, 2020
Filed:
May 21, 2019
Appl. No.:
16/417863
Inventors:
- New York NY, US
Gurkan Guntas - Harvard MA, US
Madan Katragadda - Acton MA, US
Divya Mathur - Scarsdale NY, US
Adam Reid Root - Byfield MA, US
Lidia Mosyak - Newton MA, US
Edward Roland LaVallie - Harvard MA, US
Assignee:
Pfizer Inc. - New York NY
International Classification:
C07K 16/40
A61P 35/00
Abstract:
The present invention provides novel antibodies that specifically bind to GUCY2c and uses thereof in the treatment of cancer. The present invention further provides novel bispecific antibodies comprising such antibodies and uses thereof in the treatment of cancer.

Antibodies Specific For Cd3 And Uses Thereof

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US Patent:
20190382486, Dec 19, 2019
Filed:
May 21, 2019
Appl. No.:
16/417859
Inventors:
- New York NY, US
Fang Jin - Waban MA, US
Madan Katragadda - Acton MA, US
Divya Mathur - Scarsdale NY, US
Lioudmila Gennadievna Tchistiakova - Stoneham MA, US
Assignee:
Pfizer Inc. - New York NY
International Classification:
C07K 16/28
C07K 16/46
C07K 16/30
C07K 16/40
A61P 35/00
Abstract:
The present invention provides novel antibodies that specifically bind to CD3 and uses thereof. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.
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Madan Rajyalakshmi Katragadda from Acton, MA, age ~48 Get Report