US Patent:
20090155368, Jun 18, 2009
Inventors:
Stephen Randall Holmes-Farley - Arlington MA, US
David J. Harris - Lexington MA, US
Steven C. Polomoscanik - Bedford MA, US
Adnan Salameh - Waltham MA, US
Bruce Shutts - Bolton MA, US
Richard Silva - Needham MA, US
Pradeep K. Dhal - Westford MA, US
Lynne Sole - Billerica MA, US
Assignee:
Genzyme Corporation - Cambridge MA
International Classification:
A61K 9/14
A61K 31/785
A61P 1/00
Abstract:
The present invention relates to crosslinked polyamine particles and/or pharmaceutical compositions comprising, at least in part, crosslinked polyamine particles and aggregates of such particles (including cured aggregates of crosslinked polyamine particles). The compositions may be in the form of tablets comprising, for example, particles larger than 500 μm, and used for treating patients, for example, patients with hyperphosphatemia.