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Luke Vistain Phones & Addresses

  • Bethesda, MD
  • 4919 Coyle Ave, Skokie, IL 60077
  • Evanston, IL
  • Chicago, IL
  • Gurnee, IL

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Us Patents

Mri Contrast Agents

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US Patent:
20130302258, Nov 14, 2013
Filed:
Mar 29, 2013
Appl. No.:
13/853324
Inventors:
Renee C. Strauch - Charlotte NC, US
Luke F. Vistain - Chicago IL, US
Assignee:
NORTHWESTERN UNIVERSITY - Evanston IL
International Classification:
A61K 49/10
US Classification:
424 9363
Abstract:
The present invention relates to MRI based imaging. In particular, the present invention provides MRI contrast agents targeted to a HaloTag protein with tunable relaxation properties thereby providing optimal relaxivity for low field strength imaging and the other optimal relaxivity for high field strength imaging. Moreover, the MRI contrast agents are used to detect gene expression (of a gene of interest) in real time in vivo, to detect changes in gene expression (of a gene of interest) over time in, for example, an individual organism, to detect gene expression changes (of a gene of interest) in response to therapeutics, in cell labeling for MR imaging, in clinical diagnostics, and in theranostics.
Luke F Vistain from Bethesda, MD, age ~39 Get Report