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Luke W Ashcraft

from San Francisco, CA
Age ~54
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Also known as:
Luke Williams Ashcraft, Luke W Ashcrast, Luke Ashcraft Williams, Ashcraft L Williams
Phone and address:
668 Carolina St, San Francisco, CA 94107
(415) 824-1265
Related to:
Ronnie Williams, 73Lois E Stultz, 77Kara WilliamsChris Williams, 45Isaac Williams
Connected to:
Arnold E Ashcraft, 87Becky L Ashcraft, 53Brent W Ashcraft, 44Chelsea Ashcraft, 36Conley R Ashcraft, 76Dena M Ashcraft, 54Elaine Ashcraft, 65Elsie B Ashcraft, 70Grace L Ashcraft, 95Hanna Ashcraft, 35

Luke Ashcraft Phones & Addresses

  • 668 Carolina St, San Francisco, CA 94107 (415) 824-1265
  • 238 8Th Ln, South San Francisco, CA 94080 (650) 553-9946
  • 32810 165Th St E, Llano, CA 93544
  • 10975 Crosby Rd, Harrison, OH 45030 (513) 738-2415
  • 1309 Jonathan Ct, Laurence, KS 66049 (785) 843-5046
  • Lawrence, KS

Professional Records

License Records

Luke Williams Ashcraft

Address:
668 Carolina St, San Francisco, CA 94107
License #:
A3935856
Category:
Airmen

Resumes

Resumes

Luke Ashcraft Photo 1

Scientist At Cytokinetics

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Location:
668 Carolina St, San Francisco, CA 94107
Industry:
Biotechnology
Work:
Cytokinetics
Scientist at Cytokinetics
Skills:
Drug Discovery
Biotechnology
Drug Development
Hplc
Life Sciences
Chemistry
Organic Chemistry
Assay Development
R&D
Lc Ms
Languages:
English
Luke Ashcraft Photo 2

Luke Ashcraft

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Location:
San Francisco Bay Area
Industry:
Research

Publications

Us Patents

Imidazoyl-Benzamide Anti-Cancer Agents

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US Patent:
7582668, Sep 1, 2009
Filed:
Nov 8, 2006
Appl. No.:
11/598250
Inventors:
Xiangping Qian - Foster City CA, US
Luke W. Ashcraft - San Francisco CA, US
Jianchao Wang - Foster City CA, US
Bing Yao - Millbrae CA, US
Hong Jiang - Palo Alto CA, US
Gustave Bergnes - Pacifica CA, US
Bradley P. Morgan - Moraga CA, US
Dashyant Dhanak - West Chester PA, US
Steven D. Knight - West Chester PA, US
Nicholas D. Adams - Royersford PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin J. Duffy - Philadelphia PA, US
Duke Fitch - Spring City PA, US
Rosanna Tedesco - Philadelphia PA, US
Assignee:
Cytokinetics, Incorporated - South San Francisco CA
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K 31/4178
C07D 403/10
US Classification:
514397, 5483147
Abstract:
Provided are compounds of Formula I and pharmaceutically acceptable salts thereof which may be useful for the treatment of cancer or other proliferative disorders.

Imidazopyridinyl-Benzamide Anti-Cancer Agents

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US Patent:
7618981, Nov 17, 2009
Filed:
May 3, 2005
Appl. No.:
11/121709
Inventors:
Xiangping Qian - South San Francisco CA, US
Andrew I. McDonald - South San Francisco CA, US
Han-Jie Zhou - South San Francisco CA, US
Luke W. Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
Bradley P. Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven D. Knight - Philadelphia PA, US
Nicholas D. Adams - Philadelphia PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US
Assignee:
Cytokinetics, Inc. - South San Fransico CA
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07D 471/02
A61K 31/4439
US Classification:
514300, 546121
Abstract:
Provided are compounds of Formula V and pharmaceutically acceptable salts thereof which may be useful for the treatment of cancer or other proliferative disorders.

Imidazoyl-Benzamide Anti-Cancer Agents

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US Patent:
7795448, Sep 14, 2010
Filed:
May 6, 2005
Appl. No.:
11/124608
Inventors:
Xiangping Qian - South San Francisco CA, US
Andrew I. McDonald - South San Francisco CA, US
Han-Jie Zhou - South San Francisco CA, US
Luke W. Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
Bradley P. Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven D. Knight - Philadelphia PA, US
Nicholas D. Adams - Philadelphia PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US
Assignee:
Cytokinetics, Incorporated - South San Francisco CA
International Classification:
C07D 233/64
C07D 231/12
A61K 31/415
A61K 31/4164
US Classification:
5483381, 5483751, 514399, 514406
Abstract:
Provided are compounds of Formula V and pharmaceutically acceptable salts thereof which may be useful for the treatment of cancer or other proliferative disorders.

Certain Chemical Entities, Compositions, And Methods

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US Patent:
7851484, Dec 14, 2010
Filed:
Mar 28, 2008
Appl. No.:
12/058127
Inventors:
Bradley P. Morgan - Moraga CA, US
Gustave Bergnes - Pacifica CA, US
Alex Muci - San Francisco CA, US
Scott Collibee - San Carlos CA, US
Pu-Ping Lu - Foster City CA, US
Luke W. Ashcraft - San Francisco CA, US
Marc Andrew Garard - Oakland CA, US
Assignee:
Cytokinetics, Inc. - South San Francisco CA
International Classification:
A61K 31/444
C07D 471/02
A61P 21/00
US Classification:
514303, 546118
Abstract:
Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of muscle weakness and/or cachexia, as part of a rehabilitation or conditioning exercise regimen, or in the treatment of fraility, post-polio syndrome, obesity, sarcopenia, wasting syndrome, muscle spasm, and other indications.

Certain Chemical Entities, Compositions, And Methods

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US Patent:
7989469, Aug 2, 2011
Filed:
Feb 2, 2009
Appl. No.:
12/364394
Inventors:
Zhe Yang - Daly City CA, US
Scott Collibee - San Carlos CA, US
Alex R. Muci - San Francisco CA, US
Jianchao Wang - Foster City CA, US
Luke W. Ashcraft - San Francisco CA, US
Jeff Gardina - Santa Clara CA, US
Brian Stoltz - San Marino CA, US
Gustave Bergnes - Pacifica CA, US
Bradley P. Morgan - Moraga CA, US
Assignee:
Cytokinetics, Incorporated - South San Francisco CA
International Classification:
A61K 31/437
C07D 471/04
A61P 25/00
US Classification:
514303, 546118
Abstract:
Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of neuromuscular disorders, conditions having muscle wasting, claudication, frailty, metabolic syndrome, muscle atrophy associated with disuse, and muscle fatigue, and other indications.

Imidazopyridinyl Benzamide Mitotic Kinesin Inhibitors

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US Patent:
8163919, Apr 24, 2012
Filed:
Jan 7, 2009
Appl. No.:
12/350114
Inventors:
Xiangping Qian - South San Francisco CA, US
Andrew I. McDonald - South San Francisco CA, US
Han-Jie Zhou - South San Francisco CA, US
Luke W. Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
Bradley P. Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven D. Knight - Philadelphia PA, US
Nicholas D. Adams - Philadelphia PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US
Assignee:
Cytokinetics, Incorporated - South San Francisco CA
International Classification:
C07D 471/02
A61K 31/4439
US Classification:
546121, 514300
Abstract:
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.

Imidazopyridinyl Benzamide Mitotic Kinesin Inhibitors

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US Patent:
8207340, Jun 26, 2012
Filed:
Jan 7, 2009
Appl. No.:
12/350094
Inventors:
Xiangping Qian - South San Francisco CA, US
Andrew I. McDonald - San Francisco CA, US
Han-Jie Zhou - San Francisco CA, US
Luke W. Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
Bradley P. Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven D. Knight - Philadelphia PA, US
Nicholas D. Adams - Philadelphia PA, US
Cynthia A. Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US
Assignee:
Cytokinetics, Incorporated - South San Francisco CA
International Classification:
C07D 471/02
A61K 31/47
US Classification:
546121, 514300
Abstract:
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.

Certain Chemical Entities, Compositions, And Methods

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US Patent:
20060247289, Nov 2, 2006
Filed:
Nov 9, 2005
Appl. No.:
11/271147
Inventors:
Xiangping Qian - South San Francisco CA, US
Andrew McDonald - San Francisco CA, US
Han-Jie Zhou - South San Francisco CA, US
Luke Ashcraft - South San Francisco CA, US
Bing Yao - South San Francisco CA, US
Hong Jiang - South San Francisco CA, US
Jennifer Kuo Chen Huang - South San Francisco CA, US
Jianchao Wang - South San Francisco CA, US
David Morgans - South San Francisco CA, US
Bradley Morgan - South San Francisco CA, US
Gustave Bergnes - South San Francisco CA, US
Dashyant Dhanak - Philadelphia PA, US
Steven Knight - Philadelphia PA, US
Nicholas Adams - Philadelphia PA, US
Cynthia Parrish - Philadelphia PA, US
Kevin Duffy - Philadelphia PA, US
Duke Fitch - Philadelphia PA, US
Rosanna Tedesco - Philadelphia PA, US
International Classification:
A61K 31/4184
A61K 31/4172
C07D 233/61
US Classification:
514394000, 514400000, 514614000, 548304400, 548335500, 564050000
Abstract:
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
Control profile
Luke W Ashcraft from San Francisco, CA, age ~54 Get Report