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Lucyna E Lubkowska

from Frederick, MD
Age ~60

Lucyna Lubkowska Phones & Addresses

  • 8310 Brookmere Blvd, Frederick, MD 21702 (301) 620-4125
  • Gainesville, VA
  • 8310 Brookmere Blvd, Frederick, MD 21702

Publications

Us Patents

Aspartic Protease Inhibitors

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US Patent:
7132420, Nov 7, 2006
Filed:
Jun 11, 2003
Appl. No.:
10/458873
Inventors:
Ramnarayan S. Randad - Frederick MD, US
John W. Erickson - Frederick MD, US
Michael A. Eissenstat - Frederick MD, US
Lucyna Lubkowska - Frederick MD, US
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 31/5375
A61K 31/505
C07D 413/12
C07D 239/04
US Classification:
5142355, 544106, 544111, 544224, 544242, 5462681, 5462821, 5142312, 514256, 514336, 514340
Abstract:
The present invention provides an aspartic proteinase-inhibiting compound of the formula:Further provided are pharmaceutical compositions, which include a therapeutically effective amount of at least one of the foregoing compounds, and therapeutic methods of using the foregoing compounds.

Aspartic Protease Inhibitors

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US Patent:
6613764, Sep 2, 2003
Filed:
Sep 28, 2001
Appl. No.:
09/868775
Inventors:
Ramnarayan S. Randad - Frederick MD
John W. Erickson - Frederick MD
Michael A. Eissenstat - Frederick MD
Lucyna Lubkowska - Frederick MD
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 315377
US Classification:
5142358, 514256, 514318, 544123, 544129, 544316
Abstract:
The present invention provides a compound of formula (I) wherein a, b, c, d, and e, are R , OR , SR , NR R , NHCOR , CO R , CN, NO , NH , N , or a halogen. R and R are H or alkyl, R and R are H or alkyl, and R is a non-aromatic substituent. Substituent A is OH, NH , or SH. Substituents B and B include amide and sulfonamide groups, which can be cyclic, acyclic, or amino acid derivatives. Alternatively, B and Râ together with the nitrogen to which they are bonded, and/or Bâ and R together with the nitrogen to which they are bonded, define a heterocycle. The present invention further provides a pharmaceutical composition that includes a carrier and a therapeutically effective amount of at least one compound of the present invention. The present invention further provides therapeutic methods that include administering a therapeutically effective amount of at least one compound of the present invention.
Lucyna E Lubkowska from Frederick, MD, age ~60 Get Report