US Patent:
20120263648, Oct 18, 2012
Inventors:
Bruce A. Shapiro - Gaithersburg MD, US
Yaroslava G. Yingling - Cary NC, US
Eckart Bindewald - Frederick MD, US
Wojciech Kasprzak - Frederick MD, US
Luc Jaeger - Goleta CA, US
Isil Severcan - Niskayuna NY, US
Cody Geary - Santa Barbara CA, US
Kirill Afonin - Frederick MD, US
Assignee:
REGENTS OF THE UNIVERSITY OF CALIFORNIA - Oakland CA
SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES - ROCKVILLE MD
International Classification:
A61K 49/00
A61K 47/26
C12P 19/30
C07H 1/00
A61P 31/18
A61P 25/28
A61P 19/02
A61P 11/06
A61P 9/10
A61P 35/00
A61P 9/00
A61P 3/10
A61P 31/12
A61P 9/12
A61P 3/04
A61P 25/16
A61P 1/18
A61P 29/00
A61P 1/02
C07H 21/02
B82Y 30/00
B82Y 40/00
B82Y 5/00
US Classification:
424 91, 536 231, 514777, 435 89, 536 253, 977773, 977895, 977906, 977927
Abstract:
The instant invention provides polyvalent RNA nanoparticles comprising RNA motifs as building blocks that can form RNA nanotubes. The polyvalent RNA nanoparticles are suitable for therapeutic or diagnostic use in a number of diseases or disorders.