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Lorne Malcolm Golub

from Melville, NY
Age ~84
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Also known as:
Lorne M Golub, Lorne Dr Golub, Lorne Bonny Golub, Lorne L Golub, Lorne M Golv, Bonny L Golub, Lorne B
Related to:
Beth Anne Vagle, 59Michael B Golub, 55Bonny L Golub, 82L GolubTamar K Smith, 56Vicki A Spilko, 80
Connected to:
Aharon A Golub, 96Aleksander Golub, 50Ana Golub, 86Anne Golub, 92Anton Golub, 33Bruce M Golub, 84Charlene A Golub, 70Craig L Golub, 45Cynthia R Golub, 69Dmitry L Golub, 57

Lorne Golub Phones & Addresses

  • Melville, NY
  • 10580 Royal Caribbean Cir, Boynton Beach, FL 33437 (561) 740-1953
  • 29 Whitney Gate, Smithtown, NY 11787 (631) 724-2964
  • Yorktown, VA
  • Hampton, VA
  • Newport News, VA
  • Ivanhoe, NC

Work

Position: Medical Professional

Education

Degree: Graduate or professional degree

Publications

Isbn (Books And Publications)

Inhibition of Matrix Metalloproteinases: Therapeutic Potential

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Author

Lorne M. Golub

ISBN #

0897668995

Inhibition of Matrix Metalloproteinases: Therapeutic Potential

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Author

Lorne M. Golub

ISBN #

0897669002

Us Patents

Method Of Inhibiting Cancer Growth

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US Patent:
6429204, Aug 6, 2002
Filed:
Apr 3, 2000
Appl. No.:
09/542402
Inventors:
Lorne M. Golub - Smithtown NY
Thomas F. McNamara - Morristown NY
Nungavaram S. Ramamurthy - Smithtown NY
Hsi-Ming Lee - Setauket NY
Sanford Simon - Stony Brook NY
Balakrishna L. Lokeshwar - Miami FL
Marie G. Selzer - Fort Lauderdale FL
Norman L. Block - Miami FL
Assignee:
University of Miami - Miami FL
International Classification:
A61K 3165
US Classification:
514152, 514153
Abstract:
The invention is a method of inhibiting a sarcoma, such as Kaposis sarcoma, in a mammal. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3. ).

Method For Decreasing Low Density Lipoprotein

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US Patent:
6841547, Jan 11, 2005
Filed:
Feb 28, 2003
Appl. No.:
10/377088
Inventors:
David Brown - Bronxville NY, US
Lorne M. Golub - Smithtown NY, US
Hsi-Ming Lee - Setauket NY, US
Robert Greenwald - Melville NY, US
Maria Ryan - Huntington NY, US
Kavita Desai - Bronx NY, US
Assignee:
Albert Einstein College of Medicine of Yeshevia University - Bronx NY
Montefiore Medical Center - Bronx NY
The Research Foundation of State University of New York - Albany NY
International Classification:
A61K 3165
US Classification:
514152
Abstract:
The present invention relates to a method for decreasing elevated serum/plasma LDL-cholesterol levels or LDL-cholesterol levels and CRP levels in a mammal in need thereof. The methods comprises administering an effective amount of a tetracycline formulation. In one embodiment, the tetracycline formulation is a non-antibacterial tetracycline. In another embodiment, the tetracycline formulation is an antibacterial tetracycline at a sub-antibacterial amount.

Inhibitor Of Cataract Formation

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US Patent:
6914057, Jul 5, 2005
Filed:
Sep 28, 1999
Appl. No.:
09/787866
Inventors:
Maria Emanuel Ryan - Huntington NY, US
Lorne M. Golub - Smithtown NY, US
Nungavaram S. Ramamurthy - Smithtown NY, US
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
A61K031/65
US Classification:
514152
Abstract:
Methods of reducing the risk of cataract development in a mammal are provided and include administering to the mammal an effective amount of a tetracycline derivative. A preferred tetracycline derivative administered according to the methods of the present invention is 6α-deoxy 5-hydroxy-4-dedimethylaminotetracycline.

Method Of Inhibiting Membrane-Type Matrix Metalloproteinase

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US Patent:
20020045603, Apr 18, 2002
Filed:
May 14, 2001
Appl. No.:
09/855067
Inventors:
Lorne Golub - Smithtown NY, US
Hsi-Ming Lee - Setauket NY, US
Timo Sorsa - Helsinki, FI
Olli Teronen - Helsinki, FI
Tuula Salo - Oulu, FI
Assignee:
The Research Foundation of State University of New York
International Classification:
A61K031/65
US Classification:
514/152000
Abstract:
The invention is a method of inhibiting the activity of membrane-type matrix metalloproteinase (MT-MMP) in biological systems. Accordingly, the invention permits the treatment of medical conditions in mammals that are characterized by MT-MMP activity, and especially those conditions characterized by excessive MT-MMP activity. The method employs a tetracycline compound, preferably a non-antimicrobial tetracycline, and more preferably 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3) or 6--deoxy-5-hydroxy-4-de(dimethylamino)tetracycline (CMT-8) to inhibit the MT-MMP activity.

Use Of Non-Antibacterial Tetracycline Analogs And Formulations Thereof For The Treatment Of Bacterial Exotoxins

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US Patent:
20040014731, Jan 22, 2004
Filed:
Mar 27, 2003
Appl. No.:
10/400737
Inventors:
Lorne Golub - Smithtown NY, US
Stephen Walker - East Setauket NY, US
International Classification:
A61K031/65
US Classification:
514/152000
Abstract:
The invention relates to methods for protecting and/or treating a mammal at risk of acquiring a condition associated with bacteria that produce a calmodulin exotoxin, a metalloproteinase exotoxin, or both, by administering a non-antibacterial tetracycline formulation.

Method Of Treating Sepsis-Induced Ards

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US Patent:
20040092491, May 13, 2004
Filed:
Nov 9, 2002
Appl. No.:
10/291194
Inventors:
Gary Nieman - Manlius NY, US
Sanford Simon - Stony Brook NY, US
Lorne Golub - Smithtown NY, US
Hsi-Ming Lee - Setauket NY, US
Jay Steinberg - Syracuse NY, US
Henry Schiller - Rochester MN, US
Jeff Halter - Liverpool NY, US
Anthony Picone - Manlius NY, US
William Marx - Jamesville NY, US
Louis Gatto - Cortland NY, US
Charles Lutz - Fayetteville NY, US
Assignee:
The Research Foundation of State University of New York
International Classification:
A61K031/65
US Classification:
514/152000
Abstract:
The invention is method for preventing sepsis-induced ARDS in a mammal in need thereof, the method comprises administering to the mammal a tetracycline compound in an amount that is effective to prevent sepsis-induced ARDS but has substantially no antibiotic activity.

Methods Of Treating Eczema

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US Patent:
20050148552, Jul 7, 2005
Filed:
Nov 5, 2004
Appl. No.:
10/982979
Inventors:
Maria Ryan - Laurel Hollow NY, US
Yu Liu - Guangzhou, CN
Lorne Golub - Smithtown NY, US
Hsi-Ming Lee - Setauket NY, US
Sanford Simon - Stony Brook NY, US
Stephen Walker - East Setauket NY, US
International Classification:
A61K031/65
US Classification:
514152000
Abstract:
A method of treating eczema in a human or other mammal in need thereof comprising administering systemically to said human or other mammal a tetracycline compound in an amount that is effective to treat eczema, but has substantially no antibacterial activity.

Method For Reducing C-Rective Protein Levels With Non-Antibacterial Tetracycline Formulations

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US Patent:
20050282786, Dec 22, 2005
Filed:
Jul 11, 2003
Appl. No.:
10/519534
Inventors:
David Brown - Bronxville NY, US
Lorne Golub - Smithtown NY, US
Hsi-Ming Lee - Setauket NY, US
Robert Greenwald - Melville NY, US
International Classification:
A61K031/65
US Classification:
514152000
Abstract:
The present invention is for a method for decreasing C-reactive protein levels (CRP) in a mammal in need thereof. The method comprises administering an effective amount of a non-antibacterial tetracycline formulation, to the mammal. In one embodiment, the non-antibacterial tetracycline formulation is a non-antibacterial amount of an antibacterial tetracycline. In another embodiment, the non-antibacterial tetracycline formulation is a non-antibacterial tetracycline.
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Lorne Malcolm Golub from Melville, NY, age ~84 Get Report