Inventors:
- Cambridge MA, US
Norman Wen - Newton MA, US
Daniel Levner - Brookline MA, US
Richard Novak - Jamaica Plain MA, US
Lori McPartlin - North Billerica MA, US
Donald E. Ingber - Boston MA, US
Youngjae Choe - Somerville MA, US
Lian Leng - LaSalle, CA
Justin K. Nguyen - Medford MA, US
International Classification:
C12M 3/06
C12M 3/00
C12M 1/12
C12N 5/071
C12N 5/077
Abstract:
A device for simulating a function of a tissue includes a first structure, a second structure, and a membrane. The first structure defines a first chamber. The first chamber includes a matrix disposed therein and an opened region. The second structure defines a second chamber. The membrane is located at an interface region between the first chamber and the second chamber. The membrane includes a first side facing toward the first chamber and a second side facing toward the second chamber. The membrane separates the first chamber from the second chamber.