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Lois E Bolcsak

from Lawrenceville, NJ
Age ~71
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Related to:
James W Bolcsak, 77
Connected to:
Jason Bolczak, 45Angela L Bold, 61Connie L Bold, 61Daniel J Bold, 45Gary M Bold, 60Ian R Bold, 52Jesse W Bold, 66Kathryn S Bold, 65Marc Bold, 63Matt J Bold, 33

Lois Bolcsak Phones & Addresses

  • 11 Tower Pl, Lawrence Township, NJ 08648 (609) 883-4723
  • Lawrenceville, NJ
  • Plainsboro, NJ

Work

Company: The liposome 1983 Position: Senior research fellow - inactive since 1998

Education

Degree: Doctorates, Doctor of Philosophy School / High School: University of Louisville 1983 Specialities: Toxicology, Philosophy, Pharmacology

Industries

Biotechnology

Resumes

Resumes

Lois Bolcsak Photo 1

Senior Research Fellow - Inactive Since 1998

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Location:
Trenton, NJ
Industry:
Biotechnology
Work:
The Liposome
Senior Research Fellow - Inactive Since 1998
Education:
University of Louisville 1983
Doctorates, Doctor of Philosophy, Toxicology, Philosophy, Pharmacology Iowa State University
Master of Science, Masters, Biochemistry Vassar College
Bachelors, Bachelor of Arts, Biochemistry, Chemistry

Publications

Us Patents

Steroidal Liposomes

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US Patent:
6352716, Mar 5, 2002
Filed:
Aug 18, 1993
Appl. No.:
08/108822
Inventors:
Andrew S. Janoff - Yardley PA
Mircea C. Popescu - Plainsboro NJ
Alan L. Weiner - Lawrenceville NJ
Lois E. Bolcsak - Lawrenceville NJ
Paul A. Tremblay - Hamilton NJ
Christine E. Swenson - Princeton Junction NJ
Assignee:
The Liposome Company Inc. - Princeton NJ
International Classification:
A61K 9127
US Classification:
424450, 264 41, 264 46, 424 121, 424 91, 436829, 514 78, 514182, 514887, 514967
Abstract:
Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to bompositions comprising a mixtue of tris(hydroxymethyl)aminomethane salt of cholesteryl hemisuccinate with either an antifungal compound or a peptide. These compositions have various applications in vivo.

Method For Preparing Alpha-Tocopherol Vesicles

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US Patent:
52346340, Aug 10, 1993
Filed:
Oct 17, 1990
Appl. No.:
7/599290
Inventors:
Andrew S. Janoff - Yardley PA
Lois E. Bolcsak - Lawrenceville NJ
Alan L. Weiner - Lawrenceville NJ
Paul A. Tremblay - Hamilton NJ
Michael V. W. Bergamini - Easton PA
Assignee:
The Liposome Company, Inc. - Princeton NJ
International Classification:
A61K 9127
A61K 9133
B01J 1304
US Classification:
264 41
Abstract:
Methods and compositions are described for the preparation of alpha-tocopherol vesicles, the bilayers of which comprise a salt form of an organic acid derivative of alpha-tocopherol such as the Tris salt form of alpha-tocopherol hemisuccinate. The method is rapid and efficient and does not require the use of organic solvents. The alpha-tocopherol vesicles may be used to entrap compounds which are insoluble in aqueous solutions. Such preparations are especially useful for entrapping bioactive agents of limited solubility, thus enabling administration in vivo.

Steroidal Liposomes

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US Patent:
47216123, Jan 26, 1988
Filed:
Apr 10, 1985
Appl. No.:
6/721630
Inventors:
Andrew S. Janoff - Yardley PA
Mircea C. Popescu - Plainsboro NJ
Alan L. Weiner - Plainsboro NJ
Lois E. Bolcsak - Lawrenceville NJ
Paul S. Tremblay - Hamilton NJ
Assignee:
The Liposome Company, Inc. - Princeton NJ
International Classification:
A61J 307
A61K 952
A61K 4300
B01J 1302
US Classification:
424 11
Abstract:
Methods and compositions are described for the preparation of lipid vesicles, the bilayers of which comprise a salt form of an organic acid derivative of a sterol such as the tris-salt form of a sterol hemisuccinate. The method is rapid, efficient, and does not require the use of organic solvents. The sterol hemisuccinate vesicles may be used to entrap compounds which are insoluble in aqueous solutions. Such preparations are especially useful for entrapping bioactive agents of limited solubility thus enabling administration in vivo.

Compositions Containing Tris Salt Of Cholesterol Hemisuccinate And Antifungal

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US Patent:
52311120, Jul 27, 1993
Filed:
Oct 23, 1989
Appl. No.:
7/425727
Inventors:
Andrew S. Janoff - Yardley PA
Mircea C. Popescu - Plainsboro NJ
Alan L. Weiner - Lawrenceville NJ
Lois E. Bolcsak - Lawrenceville NJ
Paul A. Tremblay - Hamilton NJ
Christine E. Swenson - Princeton Junction NJ
Assignee:
The Liposome Company, Inc. - Princeton NJ
International Classification:
A61K 31415
US Classification:
514401
Abstract:
Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to bompositions comprising a mixture of tris(hydroxymethyl)aminomethane salt of cholesteryl hemisuccinate with either an antifungal compound or a peptide. These compositions have various applications in vivo.

Liposomes Comprising Aminoglycoside Phosphates And Methods Of Production And Use

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US Patent:
54097045, Apr 25, 1995
Filed:
May 6, 1993
Appl. No.:
8/059192
Inventors:
Marcel B. Bally - Vancouver, CA
Lois E. Bolcsak - Lawrenceville NJ
Pieter R. Cullis - Vancouver, CA
Andrew S. Janoff - Yardley PA
Lawrence D. Mayer - Vancouver, CA
Assignee:
The Liposome Company, Inc. - Princeton NJ
International Classification:
A61K 9127
A61K 9133
US Classification:
424450
Abstract:
Aminoglycosides, analogs and derivatives thereof, in the form of phosphate salts are described as well as the process for making and utilizing same. Aminoglycoside phosphate liposomes and nonguanadino aminoglycoside phosphate liposomes, their preparation and use, are particularly described.

Sterodial Liposomes

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US Patent:
52884996, Feb 22, 1994
Filed:
Sep 12, 1991
Appl. No.:
7/758587
Inventors:
Andrew S. Janoff - Yardley PA
Mircea C. Popescu - Plainsboro NJ
Alan L. Weiner - Lawrenceville NJ
Lois E. Bolcsak - Lawrenceville NJ
Paul A. Tremblay - Hamilton NJ
Christine E. Swenson - Princeton Junction NJ
Assignee:
The Liposome Company, Inc. - Princeton NJ
International Classification:
A61K 9127
A61K 9133
A61K 3722
US Classification:
424450
Abstract:
Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to compositions comprising a mixture of tris(hydroxymethyl)aminomethane salt of cholesteryl hemisuccinate with either an antifungal compound or a peptide. These compositions have various applications in vivo.

Entrapment Of Water-Insoluble Compound In Alpha Tocopherol-Based Vesicles

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US Patent:
53306899, Jul 19, 1994
Filed:
Mar 29, 1993
Appl. No.:
8/039941
Inventors:
Andrew S. Janoff - Yardley PA
Lois E. Bolcsak - Lawrenceville NJ
Alan L. Weiner - Lawrenceville NJ
Paul A. Tremblay - Hamilton NJ
Michael V. W. Bergamini - Cupertino CA
Robert L. Suddith - Robbinsville NJ
Assignee:
The Liposome Company, Inc. - Princeton NJ
International Classification:
A61K 9127
A61K 9133
US Classification:
264 43
Abstract:
Methods and compositions are described for the preparation of alpha-tocopherol vesicles, the bilayers of which comprise a salt form of an organic acid derivative of alpha-tocopherol such as the Tris salt form of alpha-tocopherol hemisuccinate. The method is rapid and efficient and does not require the use of organic solvents. The alpha-tocopherol vesicles may be used to entrap compounds which are insoluble in aqueous solutions. Such preparations are especially useful for entrapping bioactive agents of limited solubility, thus enabling administration in vivo.

Alpha Tocopherol-Based Vesicles

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US Patent:
50412787, Aug 20, 1991
Filed:
Dec 6, 1988
Appl. No.:
7/280551
Inventors:
Andrew S. Janoff - Yardley PA
Lois E. Bolcsak - Lawrenceville NJ
Alan L. Weiner - Lawrenceville NJ
Paul A. Tremblay - Hamilton NJ
Michael V. W. Bergamini - Easton PA
Assignee:
The Liposome Company, Inc. - Princeton NJ
International Classification:
A61K 9139
A61K 9133
A61K 31355
A61K 4300
US Classification:
424 11
Abstract:
Methods and compositions are described for the preparation of alpha-tocopherol vesicles, the bilayers of which comprise a salt form of an organic acid derivative of alpha-tocopherol such as the Tris salt form of alpha-tocopherol hemisuccinate. The method is rapid and efficient and does not require the use of organic solvents. The alpha-tocopherol vesicles may be used to entrap compounds which are insoluble in aqueous solutions. Such preparations are especially useful for entrapping bioactive agents of limited solubility, thus enabling administration in vivo.
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Lois E Bolcsak from Lawrenceville, NJ, age ~71 Get Report