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Lizhe Xu Phones & Addresses

  • Niantic, CT
  • New Haven, CT
  • 8 Paddock Rd, East Lyme, CT 06333
  • Groton, CT
  • 3736 I 10 Service Rd, Metairie, LA 70001 (504) 888-8776 (504) 888-8779
  • 3100 17Th St, Metairie, LA 70002
  • 3008 Harvard Ave, Metairie, LA 70006 (504) 888-8776

Work

Company: Fed gov Jun 2007 Position: Scientist

Education

Degree: Doctorates, Doctor of Philosophy School / High School: University of Paris Vi 1991 to 1994 Specialities: Molecular Biology, Philosophy

Skills

Molecular Biology • Cell Culture • Lifesciences • Biochemistry • Research • Drug Discovery • Biotechnology • Science • Drug Development • Microbiology • Pcr • Cell Biology • Laboratory • Elisa

Interests

Science and Technology

Industries

Government Relations

Resumes

Resumes

Lizhe Xu Photo 1

Scientist

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Location:
8 Paddock Rd east, Lyme, CT
Industry:
Government Relations
Work:
Fed Gov
Scientist

University of New Orleans Jun 2003 - May 2006
Assistant Professor
Education:
University of Paris Vi 1991 - 1994
Doctorates, Doctor of Philosophy, Molecular Biology, Philosophy
Skills:
Molecular Biology
Cell Culture
Lifesciences
Biochemistry
Research
Drug Discovery
Biotechnology
Science
Drug Development
Microbiology
Pcr
Cell Biology
Laboratory
Elisa
Interests:
Science and Technology

Publications

Us Patents

Identification Of A Novel Retrovirus Associated With Primary Sclerosing Cholangitis And Autoimmune Hepatitis

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US Patent:
6787303, Sep 7, 2004
Filed:
Mar 28, 2000
Appl. No.:
09/536552
Inventors:
Andrew L. Mason - New Orleans LA
Lizhe Xu - Metairie LA
Linsheng Guo - Metairie LA
Assignee:
Alton Ochsner Medical Foundation - New Orleans LA
International Classification:
C12Q 170
US Classification:
435 5, 435 6, 536 231, 536 243
Abstract:
The present invention relates first, to the identification of a retrovirus and the novel nucleotide sequences encoding a retroviral polymerase gene (POL nucleotides) associated with the existence of primary sclerosing cholangitis (PSC), autoimmune hepatitis (AIH) Crohns disease and ulcerative colitis. The present invention further relates to methods for using the PSC associated retroviral nucleotides for the detection of PSC, AIH, Crohns disease and ulcerative colitis in patient samples. The present invention also relates to methods for using and targeting the PSC associated retroviral POL nucleotides in gene therapy protocols for the treatment of PSC, AIH, Crohns disease or ulcerative disease in patients in need of such treatment. The present invention further relates to diagnostic protocols and kits for the detection of PSC, AIH, Crohns disease and ulcerative colitis in tissue samples.

Compositions And Methods For Reverse Transcriptase-Polymerase Chain Reaction (Rt-Pcr) Of Human B-Retrovirus

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US Patent:
20070237716, Oct 11, 2007
Filed:
Nov 30, 2006
Appl. No.:
11/565289
Inventors:
Andrew Mason - Edmonton, CA
Lizhe Xu - Groton CT, US
International Classification:
A61K 49/00
C12Q 1/68
US Classification:
424009100, 435006000
Abstract:
The invention can be summarized as follows. The present invention provides compositions, methods and kits useful for the amplification of nucleic acid molecules from human β-retrovirus by reverse transcriptase-polymerase chain reaction (RT-PCR). Specifically, the invention provides compositions and methods for the amplification of nucleic acid molecules in a one or two-step real time RT-PCR procedure using reverse transcriptase, DNA polymerase, or a combination of both enzymes. The invention provides for the rapid and efficient amplification, detection and quantification of human β-retrovirus nucleic acids.

Identification Of A Novel Retrovirus Associated With Primary Biliary Cirrhosis And Autoimmune Disorders

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US Patent:
6468737, Oct 22, 2002
Filed:
Jun 1, 2000
Appl. No.:
09/585651
Inventors:
Andrew L. Mason - New Orleans LA
Lizhe Xu - Metairie LA
James Neuberger - Worcester, GB
Assignee:
Alton Ochsner Medical Foundation - New Orleans LA
International Classification:
C12Q 170
US Classification:
435 5, 536 2372
Abstract:
The present invention relates, first, to the discovery, identification, and characterization of novel nucleic acid molecules, that are associated with PBC, SjÃgrens syndrome, scleroderma, SLE, autoimmune thyroiditis and various other connective tissue disorders. The novel nucleotide sequences of the present invention are retroviral in origin and are indicative of a PBC retrovirus which bears a strong correlation with PBC. The present invention is based, in part, on the Applicants data which is the first evidence to suggest that PBC patients tissue may harbor a transmissible agent. The association of a retroviral infectious agent with PBC was first demonstrated by Applicants in vitro by co-culture of periportal lymph nodes derived from patients at time of transplantation and healthy biliary epithelium cells. The Applicants discoveries as described herein, report the characterization of PBC-associated infectious agent as retroviral as demonstrated by electron microscopy and immunoblot reactivity. In addition, Applicants have characterized novel nucleotide sequences which are associated with the PBC-associated retrovirus.
Lizhe Xu from Niantic, CT, age ~60 Get Report