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Lisa A Racie

from Acton, MA
Age ~58

Lisa Racie Phones & Addresses

  • 124 School St, Acton, MA 01720 (978) 266-1671
  • Belmont, MA
  • Groton, MA
  • 124 School St, Acton, MA 01720 (978) 270-3243

Work

Position: Building and Grounds Cleaning and Maintenance Occupations

Education

Degree: Bachelor's degree or higher

Publications

Us Patents

Secreted Proteins

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US Patent:
6451318, Sep 17, 2002
Filed:
Jul 26, 2000
Appl. No.:
09/625918
Inventors:
Kenneth Jacobs - Newton MA
John M. McCoy - Reading MA
Lisa A. Racie - Acton MA
Edward R. La Vallie - Tewksbury MA
David Merberg - Acton MA
Maurice Treacy - Chestnut Hill MA
Vikki Spaulding - Billerica MA
Michael J. Agostino - Andover MA
Assignee:
Genetics Institute, LLC - MA
International Classification:
A61K 3900
US Classification:
4241981
Abstract:
Novel proteins are disclosed.

Aggrecanase Molecules

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US Patent:
6689599, Feb 10, 2004
Filed:
Oct 18, 2001
Appl. No.:
09/981953
Inventors:
Lisa A. Racie - Acton MA
Natalie C. Twine - Goffstown NH
Michael J. Agostino - Andover MA
Neil Wolfman - Dover MA
Elisabeth A. Morris - Southboro MA
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
C12N 964
US Classification:
435226, 435325, 435 691, 435219, 536 232, 530350
Abstract:
Aggrecanase proteins and the nucleotides sequences encoding them as well as processes for producing them are disclosed. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

Human Sdf-5 Protein And Compositions

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US Patent:
7026445, Apr 11, 2006
Filed:
Oct 15, 1997
Appl. No.:
08/949904
Inventors:
Edward R. LaVallie - Harvard MA, US
Lisa A. Racie - Acton MA, US
Gary Hattersley - Stow MA, US
Assignee:
Genetics Institute, LLC - Cambridge MA
International Classification:
C07K 1/00
C07H 21/02
C12P 27/06
C12N 1/20
US Classification:
530350, 530361, 536 231, 435 691, 4352523
Abstract:
Purified human SDF-5 proteins and processes for producing them are disclosed. DNA molecules encoding the human SDF-5 proteins are also disclosed. The proteins may be used in regulating the binding of Wnt genes to their receptor. In preferred embodiments, the proteins may be used for inducing formation, growth, differentiation, proliferation and/or maintenance of chondrocytes and/or cartilage tissue, and for other tissue repair, such as pancreatic tissue repair.

Modified Adamts4 Molecules And Method Of Use Thereof

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US Patent:
7118902, Oct 10, 2006
Filed:
Jul 29, 2003
Appl. No.:
10/628432
Inventors:
Christopher John Corcoran - Arlington MA, US
Carl R. Flannery - Acton MA, US
Weilan Zeng - Waltham MA, US
Lisa A. Racie - Acton MA, US
Thomas McDonagh - Acton MA, US
Bethany A. Freeman - Arlington MA, US
Katy E. Georgiadis - Belmont MA, US
Edward R. LaVallie - Harvard MA, US
Assignee:
Wyeth - Madison NJ
International Classification:
C12N 15/57
C12N 9/64
C12N 15/01
C12N 15/79
US Classification:
435226, 435 691, 4352523, 4353201, 435440
Abstract:
The present invention relates to modified ADAMTS4 proteins having improved stability comparing to the corresponding native, unmodified proteins. The modified ADAMTS4 proteins can be expressed and isolated in large quantities, thus allowing further characterization of the proteins, such as crystallographic and enzyme kinetic studies. The purified, stable proteins would also facilitate the production of anti-ADAMTS antibodies and the development of inhibitors to ADAMTS enzymes.

Aggrecanase Molecules

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US Patent:
7125701, Oct 24, 2006
Filed:
Jul 26, 2002
Appl. No.:
10/205368
Inventors:
Michael J. Agostino - Andover MA, US
Lisa A. Racie - Acton MA, US
Assignee:
Wyeth - Madison NJ
International Classification:
C12N 9/48
C12Q 1/37
US Classification:
435212, 435 24
Abstract:
Novel aggrecanase proteins and the nucleotide sequences encoding them as well as processes for producing them are disclosed. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

Method Of Treatment With A Secreted Protien

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US Patent:
20010016650, Aug 23, 2001
Filed:
May 21, 1998
Appl. No.:
09/083002
Inventors:
KENNETH JACOBS - NEWTON MA, US
JOHN M. MCCOY - READING MA, US
LISA A. RACIE - ACTON MA, US
EDWARD R. LAVALLIE - HARVARD MA, US
MAURICE TREACY - CHESTNUT HILL MA, US
CHERYL EVANS - WOBURN MA, US
MICHAEL J. AGOSTINO - ANDOVER MA, US
ZHIJIAN LU - BEDFORD MA, US
DAVID MERBERG - ACTON MA, US
KEI TASHIRO - KYOTO, JP
TOMOYUKI NAKAMURA - SAN DIEGO CA, US
TAKUKU HONJO - KYOTO, JP
International Classification:
C07H021/04
A61K039/395
A61K031/545
C07K005/00
C07K007/00
C07K016/00
C07K017/00
A61K038/00
C12P021/08
US Classification:
536/023500, 530/387900, 424/130100, 530/324000
Abstract:
Novel proteins and methods of treatment using sameare disclosed.

Secreted Proteins

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US Patent:
20020106356, Aug 8, 2002
Filed:
Aug 28, 2001
Appl. No.:
09/941437
Inventors:
Kenneth Jacobs - Newton MA, US
John McCoy - Reading MA, US
Lisa Racie - Acton MA, US
Edward LaVallie - Harvard MA, US
David Merberg - Acton MA, US
Maurice Treacy - Dun Laoghaire, IE
Cheryl Evans - Germantown MD, US
International Classification:
A61K048/00
C07H021/04
US Classification:
424/093210, 514/044000, 536/023200
Abstract:
Novel proteins are disclosed.

Secreted Proteins And Polynucleotides Encoding Them

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US Patent:
20020146769, Oct 10, 2002
Filed:
Jan 7, 2002
Appl. No.:
10/040916
Inventors:
Kenneth Jacobs - Newton MA, US
John McCoy - Reading MA, US
Edward LaVallie - Tewksbury MA, US
Lisa Racie - Acton MA, US
David Merberg - Acton MA, US
Maurice Treacy - Chestnut Hill MA, US
Cheryl Evans - Brookline MA, US
Vikki Spaulding - Billerica MA, US
International Classification:
C12P021/02
C12N005/06
C07H021/04
C12N009/00
C07K014/435
US Classification:
435/069100, 435/183000, 435/320100, 435/325000, 530/350000, 536/023200
Abstract:
Novel polynucleotides and the proteins encoded thereby are disclosed.
Lisa A Racie from Acton, MA, age ~58 Get Report