Inventors:
Ian A. Wilson - La Jolla CA, US
Oded Livnah - San Diego CA, US
Enrico A. Stura - San Diego CA, US
Dana L. Johnson - Upper Black Eddy PA, US
Linda K. Jolliffe - Belle Mead NJ, US
Assignee:
The Scripps Research Institute - La Jolla CA
International Classification:
G01N 33/48
G06F 7/00
US Classification:
702 20, 702 19, 702 27, 703 11, 703 12, 707102, 435 71, 435 72
Abstract:
The invention features computer-assisted methods for identifying molecules which will bind to the EPO receptor and act as an erythropoietin (EPO) mimetic. Preferred EPO mimetics identified using the method of the invention act as agonists of the EPO receptor in one or more in vitro or in vivo biological assays of EPO activity.