Inventors:
John E. Thompson - Waterloo, CA
Tzann-Wei Wang - Waterloo, CA
Dongen Lily Lu - Exton PA, US
Assignee:
Senesco Technologies, Inc. - New Brunswick NJ
International Classification:
C12Q 1/68
C12P 19/34
C12P 33/06
C12N 9/04
C12N 15/82
C12N 15/87
A01H 5/00
US Classification:
435 6, 435 911, 435190, 435468, 435419, 435 58, 435410, 800298, 800289
Abstract:
Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced elF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced elF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.