Inventors:
James W. Tunnell - Austin TX, US
Brandon Nichols - Hutchins TX, US
Narasimhan Rajaram - Durham NC, US
Sheldon F. Bish - Austin TX, US
Liang Lim - Austin TX, US
International Classification:
G01J 3/42
G01N 21/00
G01N 21/55
G01J 3/44
US Classification:
356 51, 356319, 356 73, 356445
Abstract:
Systems comprising an optical fiber switch connected to a light source and an optical fiber probe, the optical fiber probe comprising a first optical fiber connected to the optical fiber switch and a second optical fiber connected to a spectrophotometer. Methods for determining one or more tissue parameters comprising: emitting light from a first optical fiber into a tissue; collecting the light reemitted from the tissue with a second optical fiber; generating a spectra of the light reemitted from the tissue with a spectrophotometer; and utilizing a look-up table based algorithm to determine one or more tissue parameters, wherein the lookup-table based algorithm comprises the steps of: generating a look-up table by measuring the functional form of a reflectance measured by the spectrophotometer using one or more calibration standards with known optical properties; and implementing an iterative fitting routine based on the lookup-table.
